Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15161-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15161-1-AP, RRID:AB_2161415
- Product name
- PGM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PGM1 antibody (Cat. #15161-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Vitamin C enhances the sensitivity of osteosarcoma to arsenic trioxide via inhibiting aerobic glycolysis.
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Knock-down of PGM1 inhibits cell viability, glycolysis, and oxidative phosphorylation in glioma under low glucose condition via the Myc signaling pathway.
Dual targeting of wild-type p53 and gut microbiota by Magnolol represses key metabolic process and kills CRC cells.
Lactate metabolism is essential in early-onset mitochondrial myopathy.
Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma.
PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway.
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Integrative proteomics and metabolomics approach to elucidate metabolic dysfunction induced by silica nanoparticles in hepatocytes.
Amyotrophic lateral sclerosis alters the metabolic aging profile in patient derived fibroblasts.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas.
Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures.
A novel congenital disorder of glycosylation type without central nervous system involvement caused by mutations in the phosphoglucomutase 1 gene.
Liu Y, Yue J, Ren Z, He M, Wang A, Xie J, Li T, Liu G, He X, Ge S, Yuan Y, Yang L
Toxicology and applied pharmacology 2024 Jan;482:116798
Toxicology and applied pharmacology 2024 Jan;482:116798
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Du C, Zhao S, Shan T, Han X, Jiang Q, Chen J, Gu L, Wei T, Yang T, Wang S, Wang H, Guo X, Wang L
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Knock-down of PGM1 inhibits cell viability, glycolysis, and oxidative phosphorylation in glioma under low glucose condition via the Myc signaling pathway.
Liu S, Deng Y, Yu Y, Xia X
Biochemical and biophysical research communications 2023 May 14;656:38-45
Biochemical and biophysical research communications 2023 May 14;656:38-45
Dual targeting of wild-type p53 and gut microbiota by Magnolol represses key metabolic process and kills CRC cells.
Ji H, Qiao O, Zhang Y, Wang W, Han X, Zhang X, Liu C, Gao W
Phytotherapy research : PTR 2023 Jun 16;
Phytotherapy research : PTR 2023 Jun 16;
Lactate metabolism is essential in early-onset mitochondrial myopathy.
Chen Z, Bordieanu B, Kesavan R, Lesner NP, Venigalla SSK, Shelton SD, DeBerardinis RJ, Mishra P
Science advances 2023 Jan 4;9(1):eadd3216
Science advances 2023 Jan 4;9(1):eadd3216
Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma.
Zhang W, Lyu P, Andreev D, Jia Y, Zhang F, Bozec A
Frontiers in cell and developmental biology 2022;10:974851
Frontiers in cell and developmental biology 2022;10:974851
PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway.
Zheng Z, Zhang X, Bai J, Long L, Liu D, Zhou Y
Cancer cell international 2022 May 25;22(1):201
Cancer cell international 2022 May 25;22(1):201
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Ding DX, Wang Y, Yan W, Fu WN
iScience 2022 Mar 18;25(3):103955
iScience 2022 Mar 18;25(3):103955
Integrative proteomics and metabolomics approach to elucidate metabolic dysfunction induced by silica nanoparticles in hepatocytes.
Zhu Y, Zhang Y, Li Y, Guo C, Fan Z, Li Y, Yang M, Zhou X, Sun Z, Wang J
Journal of hazardous materials 2022 Jul 15;434:128820
Journal of hazardous materials 2022 Jul 15;434:128820
Amyotrophic lateral sclerosis alters the metabolic aging profile in patient derived fibroblasts.
Gerou M, Hall B, Woof R, Allsop J, Kolb SJ, Meyer K, Shaw PJ, Allen SP
Neurobiology of aging 2021 Sep;105:64-77
Neurobiology of aging 2021 Sep;105:64-77
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
Neointimal hyperplasia in the inferior vena cava of adenine-induced chronic kidney disease rats with aortocaval fistulas.
Du J, Liang L, Liu S, Yang X, Cao S, Zhang H, Su H, Gong X, Chen Q, Kong X, Xu D
Clinical and experimental nephrology 2020 Nov;24(11):1007-1014
Clinical and experimental nephrology 2020 Nov;24(11):1007-1014
Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.
Curtis M, Kenny HA, Ashcroft B, Mukherjee A, Johnson A, Zhang Y, Helou Y, Batlle R, Liu X, Gutierrez N, Gao X, Yamada SD, Lastra R, Montag A, Ahsan N, Locasale JW, Salomon AR, Nebreda AR, Lengyel E
Cell metabolism 2019 Jan 8;29(1):141-155.e9
Cell metabolism 2019 Jan 8;29(1):141-155.e9
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
Allen SP, Hall B, Woof R, Francis L, Gatto N, Shaw AC, Myszczynska M, Hemingway J, Coldicott I, Willcock A, Job L, Hughes RM, Boschian C, Bayatti N, Heath PR, Bandmann O, Mortiboys H, Ferraiuolo L, Shaw PJ
Brain : a journal of neurology 2019 Dec 1;142(12):3771-3790
Brain : a journal of neurology 2019 Dec 1;142(12):3771-3790
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures.
Elhassan YS, Kluckova K, Fletcher RS, Schmidt MS, Garten A, Doig CL, Cartwright DM, Oakey L, Burley CV, Jenkinson N, Wilson M, Lucas SJE, Akerman I, Seabright A, Lai YC, Tennant DA, Nightingale P, Wallis GA, Manolopoulos KN, Brenner C, Philp A, Lavery GG
Cell reports 2019 Aug 13;28(7):1717-1728.e6
Cell reports 2019 Aug 13;28(7):1717-1728.e6
A novel congenital disorder of glycosylation type without central nervous system involvement caused by mutations in the phosphoglucomutase 1 gene.
Pérez B, Medrano C, Ecay MJ, Ruiz-Sala P, Martínez-Pardo M, Ugarte M, Pérez-Cerdá C
Journal of inherited metabolic disease 2013 May;36(3):535-42
Journal of inherited metabolic disease 2013 May;36(3):535-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 15161-1-AP(PGM1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using PGM1 antibody 15161-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15161-1-AP(PGM1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15161-1-AP(PGM1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue