BS7269

antibody from Bioworld Technology, Inc
Targeting: TK1
Provider product page for BS7269
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7269 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TK polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TK.
Description
Thymidine kinase 2 (TK2) salvages mitochondrial (mt) pyrimidine deoxynucleosides for mtDNA precursor synthesis. TK2 phosphorylates these nucleosides to their corresponding nucleoside monophosphates using a nucleotide triphosphate as a donor. Deficiency of mitochondrial TK2 manifests as severe skeletal myopathy during infancy, due to depletion of mtDNA. Mutant enzyme possesses similar K(m) values to wild type, however, the V(max) is markedly decreased, leading to the decreased enzyme efficiency, which causes the disease.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TK1 protein structure - BS7269 shown in red.