Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10471-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10471-1-AP, RRID:AB_2091446
- Product name
- DHCR24 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DHCR24 antibody (Cat. #10471-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Distinctive genes and signaling pathways associated with type 2 diabetes-related periodontitis: Preliminary study.
ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2.
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.
Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.
The alterations of miRNA and mRNA expression profile and their integration analysis induced by silica nanoparticles in spermatocyte cells.
Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.
Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation.
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Dhcr24 activates the PI3K/Akt/HKII pathway and protects against dilated cardiomyopathy in mice.
3β-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species.
Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.
Duarte PM, Gurgel BCV, Miranda TS, Sardenberg J, Gu T, Aukhil I
PloS one 2024;19(1):e0296925
PloS one 2024;19(1):e0296925
ALOX15B controls macrophage cholesterol homeostasis via lipid peroxidation, ERK1/2 and SREBP2.
Benatzy Y, Palmer MA, Lütjohann D, Ohno RI, Kampschulte N, Schebb NH, Fuhrmann DC, Snodgrass RG, Brüne B
Redox biology 2024 Jun;72:103149
Redox biology 2024 Jun;72:103149
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
Sun Q, Liu D, Cui W, Cheng H, Huang L, Zhang R, Gu J, Liu S, Zhuang X, Lu Y, Chu B, Li J
Communications biology 2023 Nov 1;6(1):1108
Communications biology 2023 Nov 1;6(1):1108
Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.
Hu Z, Yuan Y, Tong Z, Liao M, Yuan S, Wu W, Tang Y, Wang Y, Tang C, Liu W
International journal of molecular sciences 2023 Aug 16;24(16)
International journal of molecular sciences 2023 Aug 16;24(16)
Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.
Yang XB, Zu HB, Zhao YF, Yao K
Frontiers in aging neuroscience 2021;13:766410
Frontiers in aging neuroscience 2021;13:766410
The alterations of miRNA and mRNA expression profile and their integration analysis induced by silica nanoparticles in spermatocyte cells.
Zhou G, Ren L, Yin H, Liu J, Li X, Wang J, Li Y, Sang Y, Zhao Y, Zhou X, Sun Z
NanoImpact 2021 Jul;23:100348
NanoImpact 2021 Jul;23:100348
Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.
Hartwig C, Méndez GM, Bhattacharjee S, Vrailas-Mortimer AD, Zlatic SA, Freeman AAH, Gokhale A, Concilli M, Werner E, Sapp Savas C, Rudin-Rush S, Palmer L, Shearing N, Margewich L, McArthy J, Taylor S, Roberts B, Lupashin V, Polishchuk RS, Cox DN, Jorquera RA, Faundez V
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 13;41(2):215-233
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 13;41(2):215-233
Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation.
Snodgrass RG, Benatzy Y, Schmid T, Namgaladze D, Mainka M, Schebb NH, Lütjohann D, Brüne B
Cell death and differentiation 2021 Apr;28(4):1301-1316
Cell death and differentiation 2021 Apr;28(4):1301-1316
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao X, Luo J, Qi W, Song BL
Nature 2020 Dec;588(7838):479-484
Nature 2020 Dec;588(7838):479-484
Dhcr24 activates the PI3K/Akt/HKII pathway and protects against dilated cardiomyopathy in mice.
Dong W, Guan FF, Zhang X, Gao S, Liu N, Chen W, Zhang LF, Lu D
Animal models and experimental medicine 2018 Mar;1(1):40-52
Animal models and experimental medicine 2018 Mar;1(1):40-52
3β-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species.
Mirza R, Qiao S, Tateyama K, Miyamoto T, Xiuli L, Seo H
Journal of bone and mineral metabolism 2012 Mar;30(2):144-53
Journal of bone and mineral metabolism 2012 Mar;30(2):144-53
Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.
Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T
Immunology 2010 Sep;131(1):59-66
Immunology 2010 Sep;131(1):59-66
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.
Legg RL, Tolman JR, Lovinger CT, Lephart ED, Setchell KD, Christensen MJ
Reproductive biology and endocrinology : RB&E 2008 Nov 24;6:57
Reproductive biology and endocrinology : RB&E 2008 Nov 24;6:57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10471-1-AP(DHCR24 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Seladin 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Seladin 1. This antibody recognizes human,mouse,rat antigen. The Seladin 1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.