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- Product number
- 13126-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13126-1-AP, RRID:AB_2212761
- Product name
- USP24 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP24 antibody (Cat. #13126-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NCI677397 targeting USP24-mediated induction of lipid peroxidation induces ferroptosis in drug-resistant cancer cells.
USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy.
Upregulation of NF-κB by USP24 aggravates ferroptosis in diabetic cardiomyopathy.
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer.
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.
USP24 promotes drug resistance during cancer therapy.
USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy.
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability.
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy.
Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.
USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.
Wang SA, Wu YC, Yang FM, Hsu FL, Zhang K, Hung JJ
Molecular oncology 2024 Sep;18(9):2255-2276
Molecular oncology 2024 Sep;18(9):2255-2276
USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy.
Young MJ, Wang SA, Chen YC, Liu CY, Hsu KC, Tang SW, Tseng YL, Wang YC, Lin SM, Hung JJ
Cell death and differentiation 2024 May;31(5):574-591
Cell death and differentiation 2024 May;31(5):574-591
Upregulation of NF-κB by USP24 aggravates ferroptosis in diabetic cardiomyopathy.
Wu S, Zhou Y, Liang J, Ying P, Situ Q, Tan X, Zhu J
Free radical biology & medicine 2024 Jan;210:352-366
Free radical biology & medicine 2024 Jan;210:352-366
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Zang L, Gu J, Yang X, Yuan Y, Guo H, Zhou W, Ma J, Chen Y, Wu Y, Zheng H, Shi W
Virologica Sinica 2023 Feb;38(1):75-83
Virologica Sinica 2023 Feb;38(1):75-83
LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer.
Sun Z, Zhang R, Zhang X, Sun Y, Liu P, Francoeur N, Han L, Lam WY, Yi Z, Sebra R, Walsh M, Yu J, Zhang W
Molecular cancer 2022 Jul 16;21(1):147
Molecular cancer 2022 Jul 16;21(1):147
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.
He H, Yi L, Zhang B, Yan B, Xiao M, Ren J, Zi D, Zhu L, Zhong Z, Zhao X, Jin X, Xiong W
International journal of biological sciences 2021;17(10):2417-2429
International journal of biological sciences 2021;17(10):2417-2429
USP24 promotes drug resistance during cancer therapy.
Wang SA, Young MJ, Wang YC, Chen SH, Liu CY, Lo YA, Jen HH, Hsu KC, Hung JJ
Cell death and differentiation 2021 Sep;28(9):2690-2707
Cell death and differentiation 2021 Sep;28(9):2690-2707
USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy.
Wang SA, Young MJ, Jeng WY, Liu CY, Hung JJ
Scientific reports 2020 Nov 30;10(1):20870
Scientific reports 2020 Nov 30;10(1):20870
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Kim JM, Yang YS, Park KH, Ge X, Xu R, Li N, Song M, Chun H, Bok S, Charles JF, Filhol-Cochet O, Boldyreff B, Dinter T, Yu PB, Kon N, Gu W, Takarada T, Greenblatt MB, Shim JH
Nature communications 2020 May 8;11(1):2289
Nature communications 2020 May 8;11(1):2289
The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability.
Thayer JA, Awad O, Hegdekar N, Sarkar C, Tesfay H, Burt C, Zeng X, Feldman RA, Lipinski MM
Autophagy 2020 Jan;16(1):140-153
Autophagy 2020 Jan;16(1):140-153
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Bufalieri F, Infante P, Bernardi F, Caimano M, Romania P, Moretti M, Lospinoso Severini L, Talbot J, Melaiu O, Tanori M, Di Magno L, Bellavia D, Capalbo C, Puget S, De Smaele E, Canettieri G, Guardavaccaro D, Busino L, Peschiaroli A, Pazzaglia S, Giannini G, Melino G, Locatelli F, Gulino A, Ayrault O, Fruci D, Di Marcotullio L
Nature communications 2019 Jul 24;10(1):3304
Nature communications 2019 Jul 24;10(1):3304
USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy.
Wang YC, Wu YS, Hung CY, Wang SA, Young MJ, Hsu TI, Hung JJ
Nature communications 2018 Sep 28;9(1):3996
Nature communications 2018 Sep 28;9(1):3996
Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.
Sun Y, Bao Q, Xuan B, Xu W, Pan D, Li Q, Qian Z
Journal of virology 2018 Jul 1;92(13)
Journal of virology 2018 Jul 1;92(13)
USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.
Engel K, Rudelius M, Slawska J, Jacobs L, Ahangarian Abhari B, Altmann B, Kurutz J, Rathakrishnan A, Fernández-Sáiz V, Brunner A, Targosz BS, Loewecke F, Gloeckner CJ, Ueffing M, Fulda S, Pfreundschuh M, Trümper L, Klapper W, Keller U, Jost PJ, Rosenwald A, Peschel C, Bassermann F
EMBO molecular medicine 2016 Aug;8(8):851-62
EMBO molecular medicine 2016 Aug;8(8):851-62
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 13126-1-AP(USP24 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using USP24 antibody 13126-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
