Antibody data
- Antibody Data
- Antigen structure
- References [59]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22245-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22245-1-AP, RRID:AB_11182388
- Product name
- STK4/MST1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STK4/MST1 antibody (Cat. #22245-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phase separation of OPTN initiates mitophagy to orchestrate craniofacial bone mineralization.
Total flavonoids from Carthamus tinctorius L. inhibit the liver fibrosis progression via Hippo/YAP pathway.
Jianpi Jiedu Xiaozheng Fang Regulates Hepatocellular Carcinoma Proliferation and Metastasis Based on Network Pharmacology.
Small Nucleolar RNA Snord17 Promotes Self-Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation.
Ginsenoside Rg1 ameliorates lipopolysaccharide-induced depressive-like behaviors in mice by attenuating neuroinflammation and neuronal damage.
A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance.
Effects of Electroacupuncture Stimulation on Motor Function Recovery in Mice After Spinal Cord Injury by Regulating Astrocyte Activation.
High viscosity microenvironment induces chemoresistance of cancer cells through upregulating P-gp.
Leonurine Attenuates CCl(4)-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway.
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells.
Elucidating the correlation between polychlorinated dibenzo-p-dioxins and prostate cancer progression: Insights from gene expression and molecular docking.
The protective role of quercetin in cataract lenses and its mechanisms related to the hippo signaling pathway.
CDK11 Promotes Paclitaxel Resistance in Cervical Cancer by Regulating LATS1-Mediated Hippo Signaling Pathway Through Phosphorylation of NF2.
Microcystin-LR facilitates pubertal bone retardation by interfering with glutamine metabolism to accelerate stem cell senescence through Hippo/GLS pathway.
MS4A1 regulates M1-polarized tumor-associated macrophage infiltration, angiogenesis, and cancer progression through the HIPPO pathway in lung adenocarcinoma.
Melatonin regulates the MST1/Nrf2 pathway to alleviate oxidative stress injury after hypoxic-ischemic brain damage in neonatal rats.
Mechanism of action of HuPoSan on EMs rats as revealed by multi-omics combined with network pharmacology.
MISP promotes the progression of lung adenocarcinoma through Inhibition of the Hippo signaling pathway.
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation.
Mixed exposure to PFOA and PFOS induces oocyte apoptosis and subfertility in mice by activating the Hippo signaling pathway.
Mesenchymal stromal/stem cell spheroid-derived extracellular vesicles advance the therapeutic efficacy of 3D-printed vascularized artificial liver lobules in liver failure treatment.
Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma.
circGAPVD1 inhibits the progression of gastric cancer through miR-4424/STK4 axis and encoding GAPVD1-137aa protein.
Overcoming immunotherapy resistance in bladder cancer with a novel antibody-drug conjugate RC48.
RASSF4 Attenuates Metabolic Dysfunction-Associated Steatotic Liver Disease Progression via Hippo Signaling and Suppresses Hepatocarcinogenesis.
CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC.
METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer.
TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway.
Endometrial stem cell-derived exosomes repair cisplatin-induced premature ovarian failure via Hippo signaling pathway.
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
Hippo pathway activated by circulating reactive oxygen species mediates cardiac diastolic dysfunction after acute kidney injury.
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
The Inhibition of γ-Aminobutyric Acid B1 Receptor Regulates Angiogenesis via the Hippo/YAP Signaling Pathway.
Targeting mechanics-induced trabecular meshwork dysfunction through YAP-TGFβ Ameliorates high myopia-induced ocular hypertension.
Oleanolic acid, a small-molecule natural product, inhibits ECM degeneration in osteoarthritis by regulating the Hippo/YAP and Wnt/β-catenin pathways.
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Ring finger protein 128 promotes, rather than inhibits, colorectal cancer progression by regulating the Hippo signaling pathway.
A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma.
Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis.
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Fibroblast growth factor 18 attenuates liver fibrosis and HSCs activation via the SMO-LATS1-YAP pathway.
Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway.
NGF Signaling Interacts With the Hippo/YAP Pathway to Regulate Cervical Cancer Progression.
Glycogen accumulation and phase separation drives liver tumor initiation.
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
Hippo kinases MST1 and MST2 control the differentiation of the epididymal initial segment via the MEK-ERK pathway.
Gut microbiota transplantation from db/db mice induces diabetes-like phenotypes and alterations in Hippo signaling in pseudo germ-free mice.
LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas.
Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms.
Differential Levels of Hippo Signaling in Selected Brain and Peripheral Tissues in Streptozotocin-Induced Cognitive Dysfunction in Mice.
Alginate oligosaccharide attenuates α2,6-sialylation modification to inhibit prostate cancer cell growth via the Hippo/YAP pathway.
Expression of Hippo signaling pathway components in Hu sheep male reproductive tract and spermatozoa.
Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis.
Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation.
REGγ deficiency suppresses tumor progression via stabilizing CK1ε in renal cell carcinoma.
Energy restriction affect liver development in Hu sheep ram lambs through Hippo signaling pathway.
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Liu H, Lu Z, Zhang X, Wang Y, Ge X, Chen S, Shi Y, Yan J, Xu R, Ma J, Guo S
Autophagy 2026 May;22(5):1021-1043
Autophagy 2026 May;22(5):1021-1043
Total flavonoids from Carthamus tinctorius L. inhibit the liver fibrosis progression via Hippo/YAP pathway.
Bao X, Zhao X, Wang H, Yuan H, Jin R, Li M, Wang Y, Ma Y
Journal of natural medicines 2026 Mar;80(2):288-300
Journal of natural medicines 2026 Mar;80(2):288-300
Jianpi Jiedu Xiaozheng Fang Regulates Hepatocellular Carcinoma Proliferation and Metastasis Based on Network Pharmacology.
Li B, Shi HQ, Luo R, Zhang ZQ, Dong XC, Li XH, Ye SQ, Zhong C
Journal of cellular and molecular medicine 2026 Mar;30(5):e71040
Journal of cellular and molecular medicine 2026 Mar;30(5):e71040
Small Nucleolar RNA Snord17 Promotes Self-Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation.
Zhang P, Xu Y, Lan Y, Xiong Z, Yi Z, Wu R, Li C, Du Y, Guo H, Yang Y, Fan Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e12029
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e12029
Ginsenoside Rg1 ameliorates lipopolysaccharide-induced depressive-like behaviors in mice by attenuating neuroinflammation and neuronal damage.
Zhang L, Tang J, Fang Z, Wang G, Wang N, Chen H, Pei L
Scientific reports 2026 Mar 3;16(1)
Scientific reports 2026 Mar 3;16(1)
A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance.
Wang Y, Liu X, Li X, Zhao L, Chen H, Gong X, Xu J, Zhang J, Liu Z, Sun Y
Science translational medicine 2026 Feb 25;18(838):eadz0672
Science translational medicine 2026 Feb 25;18(838):eadz0672
Effects of Electroacupuncture Stimulation on Motor Function Recovery in Mice After Spinal Cord Injury by Regulating Astrocyte Activation.
Zhong HZ, Cheng L, Tian DS, Jiang Y, Jing JH, Wu ZH, Zhou Y
Neurochemical research 2026 Feb 23;51(2)
Neurochemical research 2026 Feb 23;51(2)
High viscosity microenvironment induces chemoresistance of cancer cells through upregulating P-gp.
Zhou G, Wu C, Zhang W
International journal of pharmaceutics 2026 Apr 10;694:126753
International journal of pharmaceutics 2026 Apr 10;694:126753
Leonurine Attenuates CCl(4)-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway.
Wang P, Bai J, Ye M, Huang Z, Chen J, Sun L, Zhong X, Zheng Y, Ma T, Fu W, Du Y
Drug design, development and therapy 2025;19:6553-6571
Drug design, development and therapy 2025;19:6553-6571
Mst1 inhibition mitigates steroid-induced femoral head osteonecrosis by modulating autophagy in bone microvascular endothelial cells.
Zhang Y, Jiang T, Li B, Sun G, Wang Y, Jiang Y, Hua P, Mu X, Wang W, Zhang Q
Biochemical pharmacology 2025 Sep;239:117081
Biochemical pharmacology 2025 Sep;239:117081
Elucidating the correlation between polychlorinated dibenzo-p-dioxins and prostate cancer progression: Insights from gene expression and molecular docking.
Lin F, Wei Y, Chen CR, Zheng WC, Lin B, Ke ZB, Wu YP, Li XD, Zheng QS, Xue XY, Xu N
Ecotoxicology and environmental safety 2025 Sep 15;303:119009
Ecotoxicology and environmental safety 2025 Sep 15;303:119009
The protective role of quercetin in cataract lenses and its mechanisms related to the hippo signaling pathway.
Miao S, Feng Z
International ophthalmology 2025 Oct 9;45(1):409
International ophthalmology 2025 Oct 9;45(1):409
CDK11 Promotes Paclitaxel Resistance in Cervical Cancer by Regulating LATS1-Mediated Hippo Signaling Pathway Through Phosphorylation of NF2.
Zhang Y, Lu J, Qi M, Zhang X, Ou D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71085
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71085
Microcystin-LR facilitates pubertal bone retardation by interfering with glutamine metabolism to accelerate stem cell senescence through Hippo/GLS pathway.
Pan C, Liu T, Fan Z, Ma B, Wang K, Wang X, Zhang Y, Hong R, Chen H
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126931
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126931
MS4A1 regulates M1-polarized tumor-associated macrophage infiltration, angiogenesis, and cancer progression through the HIPPO pathway in lung adenocarcinoma.
Gao W, Wang R, Yang S, Shi Y, Cui M, Jiang R, Li R, Yu Y, Jia D, Che D
Cancer immunology, immunotherapy : CII 2025 Nov 3;74(12):356
Cancer immunology, immunotherapy : CII 2025 Nov 3;74(12):356
Melatonin regulates the MST1/Nrf2 pathway to alleviate oxidative stress injury after hypoxic-ischemic brain damage in neonatal rats.
Zhang Y, Gao W, Jing X, Shang W, Wang X, Yu S
Neurological research 2025 Nov 28;:1-14
Neurological research 2025 Nov 28;:1-14
Mechanism of action of HuPoSan on EMs rats as revealed by multi-omics combined with network pharmacology.
Huo C, Li F, Guo L, Sun X, Guo Y, Chen X, Liu K, Wang C, Zhang C, Zhang W, Li J, Yang Y, Wang H, Zou X, Ma X, Zhai C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157480
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157480
MISP promotes the progression of lung adenocarcinoma through Inhibition of the Hippo signaling pathway.
Cheng Y, Shen Y, Fang W, Duan S, Wang Y, Dai X, Chen Y
Discover oncology 2025 Nov 17;16(1):2116
Discover oncology 2025 Nov 17;16(1):2116
Macrophage Notch1 drives septic cardiac dysfunction by impairing mitophagy and promoting NLRP3 activation.
Zheng Y, Lin J, Wan G, Gu X, Ma J
Biology direct 2025 May 26;20(1):65
Biology direct 2025 May 26;20(1):65
Mixed exposure to PFOA and PFOS induces oocyte apoptosis and subfertility in mice by activating the Hippo signaling pathway.
Yan XZ, Peng J, Liu YQ, Fan RN, Ni XY, Gong L, Zhang DN, Huang X, Tan SH, Wang HL
Reproductive toxicology (Elmsford, N.Y.) 2025 Mar;132:108829
Reproductive toxicology (Elmsford, N.Y.) 2025 Mar;132:108829
Mesenchymal stromal/stem cell spheroid-derived extracellular vesicles advance the therapeutic efficacy of 3D-printed vascularized artificial liver lobules in liver failure treatment.
Zhang J, Chen X, Chai Y, Jin Y, Li F, Zhuo C, Xu Y, Wang H, Ju E, Lao YH, Xie X, Li M, Tao Y
Bioactive materials 2025 Jul;49:121-139
Bioactive materials 2025 Jul;49:121-139
Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma.
Nan N
Toxicology and applied pharmacology 2025 Jan;494:117181
Toxicology and applied pharmacology 2025 Jan;494:117181
circGAPVD1 inhibits the progression of gastric cancer through miR-4424/STK4 axis and encoding GAPVD1-137aa protein.
Zhu L, Yao Z, Liu Y, Shao S, Zhou W, Ding J, Mao B, Shao C, Cui F
International journal of biological macromolecules 2025 Aug;319(Pt 3):145408
International journal of biological macromolecules 2025 Aug;319(Pt 3):145408
Overcoming immunotherapy resistance in bladder cancer with a novel antibody-drug conjugate RC48.
Xiao J, Liu J, Zhang C, Liu Z, Nie Z, Yi Z, Gao X, Liang H, Huang J, Cai Z, Yan L, Wu B, Liu Z, Chen J, Zu X, Hu J
Journal for immunotherapy of cancer 2025 Aug 11;13(8)
Journal for immunotherapy of cancer 2025 Aug 11;13(8)
RASSF4 Attenuates Metabolic Dysfunction-Associated Steatotic Liver Disease Progression via Hippo Signaling and Suppresses Hepatocarcinogenesis.
Xu C, Fang T, Qu J, Miao Y, Tian L, Zhang M, Zhuang H, Sun B, Chen L
Cellular and molecular gastroenterology and hepatology 2024;18(2):101348
Cellular and molecular gastroenterology and hepatology 2024;18(2):101348
CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC.
Zhang S, Wang J, Chen Y, Liang W, Liu H, Du R, Sun Y, Hu C, Shang Z
Cell & bioscience 2024 Nov 27;14(1):144
Cell & bioscience 2024 Nov 27;14(1):144
METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer.
Bai X, Liu J, Zhou S, Wu L, Feng X, Zhang P
Journal of experimental & clinical cancer research : CR 2024 Nov 20;43(1):307
Journal of experimental & clinical cancer research : CR 2024 Nov 20;43(1):307
TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway.
Shu B, Zhou Y, Lei G, Peng Y, Ding C, Li Z, He C
Cancer science 2024 May;115(5):1476-1491
Cancer science 2024 May;115(5):1476-1491
Endometrial stem cell-derived exosomes repair cisplatin-induced premature ovarian failure via Hippo signaling pathway.
Wang L, Wang L, Wang R, Xu T, Wang J, Cui Z, Cheng F, Wang W, Yang X
Heliyon 2024 May 30;10(10):e31639
Heliyon 2024 May 30;10(10):e31639
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
Wang R, Cheng F, Yang X
Journal of ovarian research 2024 Mar 15;17(1):62
Journal of ovarian research 2024 Mar 15;17(1):62
Hippo pathway activated by circulating reactive oxygen species mediates cardiac diastolic dysfunction after acute kidney injury.
Han X, Hong Q, Peng F, Zhang Y, Wu L, Wang X, Zheng Y, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167184
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167184
Blocking the interaction between circTNRC18 and LIN28A promotes trophoblast epithelial-mesenchymal transformation and alleviates preeclampsia.
Chen LL, Li YQ, Kang ZH, Zhang X, Gu SY, Wang N, Shen XY
Molecular and cellular endocrinology 2024 Jan 1;579:112073
Molecular and cellular endocrinology 2024 Jan 1;579:112073
The Inhibition of γ-Aminobutyric Acid B1 Receptor Regulates Angiogenesis via the Hippo/YAP Signaling Pathway.
Chen B, Chen J, Shen Z, Wang W, Li J, Liu S, Cai H, Lu S
Annals of vascular surgery 2024 Dec;109:370-381
Annals of vascular surgery 2024 Dec;109:370-381
Targeting mechanics-induced trabecular meshwork dysfunction through YAP-TGFβ Ameliorates high myopia-induced ocular hypertension.
Bu Q, Zhu H, Cao G, Gong G, Su Y, Ge Q, Zhu W, Li Z, Pan X
Experimental eye research 2024 Apr;241:109853
Experimental eye research 2024 Apr;241:109853
Oleanolic acid, a small-molecule natural product, inhibits ECM degeneration in osteoarthritis by regulating the Hippo/YAP and Wnt/β-catenin pathways.
Ma T, Ruan H, Lv L, Wei C, Yu Y, Jia L, Song X, Zhang J, Li Y
Food & function 2023 Nov 13;14(22):9999-10013
Food & function 2023 Nov 13;14(22):9999-10013
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Bu J, Zhang Y, Wu S, Li H, Sun L, Liu Y, Zhu X, Qiao X, Ma Q, Liu C, Niu N, Xue J, Chen G, Yang Y, Liu C
Nature communications 2023 May 5;14(1):2602
Nature communications 2023 May 5;14(1):2602
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
Ameliorative effects of different doses of selenium against fluoride-triggered apoptosis and oxidative stress-mediated renal injury in rats through the activation of Nrf2/HO-1/NQO1 signaling pathway.
Hu Y, Yan Z, He Y, Li Y, Li M, Li Y, Zhang D, Zhao Y, Ommati MM, Wang J, Huo M, Wang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113647
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113647
Ring finger protein 128 promotes, rather than inhibits, colorectal cancer progression by regulating the Hippo signaling pathway.
Ning S, Chen Y, Wang G, Liu Y, Yang Y, Zhang Z
Frontiers in oncology 2022;12:1031160
Frontiers in oncology 2022;12:1031160
A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma.
Zhang J, Tong Y, Lu X, Dong F, Ma X, Yin S, He Y, Liu Y, Liu Q, Fan D
Life sciences 2022 Sep 1;304:120698
Life sciences 2022 Sep 1;304:120698
Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis.
Chen S, Zhang L, Li M, Zhang Y, Sun M, Wang L, Lin J, Cui Y, Chen Q, Jin C, Li X, Wang B, Chen H, Zhou T, Wang L, Hsu CH, Zhuo W
Nature communications 2022 Mar 10;13(1):1248
Nature communications 2022 Mar 10;13(1):1248
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Li Y, Yang J, Zhang Q, Xu S, Sun W, Ge S, Xu X, Jager MJ, Jia R, Zhang J, Fan X
Oncogene 2022 Jul;41(27):3539-3553
Oncogene 2022 Jul;41(27):3539-3553
Fibroblast growth factor 18 attenuates liver fibrosis and HSCs activation via the SMO-LATS1-YAP pathway.
Tong G, Chen X, Lee J, Fan J, Li S, Zhu K, Hu Z, Mei L, Sui Y, Dong Y, Chen R, Jin Z, Zhou B, Li X, Wang X, Cong W, Huang P, Jin L
Pharmacological research 2022 Apr;178:106139
Pharmacological research 2022 Apr;178:106139
Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway.
Fu Y, Wan P, Zhang J, Li X, Xing J, Zou Y, Wang K, Peng H, Zhu Q, Cao L, Zhai X
Frontiers in cell and developmental biology 2021;9:741060
Frontiers in cell and developmental biology 2021;9:741060
NGF Signaling Interacts With the Hippo/YAP Pathway to Regulate Cervical Cancer Progression.
Wang L, Li J, Wang R, Chen H, Wang R, Wang W, Yang X
Frontiers in oncology 2021;11:688794
Frontiers in oncology 2021;11:688794
Glycogen accumulation and phase separation drives liver tumor initiation.
Liu Q, Li J, Zhang W, Xiao C, Zhang S, Nian C, Li J, Su D, Chen L, Zhao Q, Shao H, Zhao H, Chen Q, Li Y, Geng J, Hong L, Lin S, Wu Q, Deng X, Ke R, Ding J, Johnson RL, Liu X, Chen L, Zhou D
Cell 2021 Oct 28;184(22):5559-5576.e19
Cell 2021 Oct 28;184(22):5559-5576.e19
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
Zheng YW, Li ZH, Lei L, Liu CC, Wang Z, Fei LR, Yang MQ, Huang WJ, Xu HT
Frontiers in oncology 2020;10:180
Frontiers in oncology 2020;10:180
Hippo kinases MST1 and MST2 control the differentiation of the epididymal initial segment via the MEK-ERK pathway.
Meng C, Tian G, Xu C, Li X, Zhang Y, Wang Y, Qin J, Fok EKL, Hinton BT, Mak KK, Shum WW, Chan WY, Xia Y
Cell death and differentiation 2020 Oct;27(10):2797-2809
Cell death and differentiation 2020 Oct;27(10):2797-2809
Gut microbiota transplantation from db/db mice induces diabetes-like phenotypes and alterations in Hippo signaling in pseudo germ-free mice.
Yu F, Jiang R, Han W, Zhan G, Xu X, Jiang X, Wang L, Xiang S, Zhou Q, Liu C, Zhu B, Hua F, Yang C
Aging 2020 Nov 20;12(23):24156-24167
Aging 2020 Nov 20;12(23):24156-24167
LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas.
Li W, Dai Y, Shi B, Yue F, Zou J, Xu G, Jiang X, Wang F, Zhou X, Liu L
Oncogene 2020 May;39(19):3879-3892
Oncogene 2020 May;39(19):3879-3892
Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms.
Xu C, Wang L, Zhang Y, Li W, Li J, Wang Y, Meng C, Qin J, Zheng ZH, Lan HY, Mak KK, Huang Y, Xia Y
Journal of the American Society of Nephrology : JASN 2020 May;31(5):946-961
Journal of the American Society of Nephrology : JASN 2020 May;31(5):946-961
Differential Levels of Hippo Signaling in Selected Brain and Peripheral Tissues in Streptozotocin-Induced Cognitive Dysfunction in Mice.
Yu F, Han W, Zhan G, Li S, Jiang X, Xiang S, Zhu B, Yang L, Hua D, Luo A, Hua F, Yang C
Neuroscience 2019 Nov 21;421:48-58
Neuroscience 2019 Nov 21;421:48-58
Alginate oligosaccharide attenuates α2,6-sialylation modification to inhibit prostate cancer cell growth via the Hippo/YAP pathway.
Han Y, Zhang L, Yu X, Wang S, Xu C, Yin H, Wang S
Cell death & disease 2019 May 10;10(5):374
Cell death & disease 2019 May 10;10(5):374
Expression of Hippo signaling pathway components in Hu sheep male reproductive tract and spermatozoa.
Zhang GM, Zhang TT, An SY, El-Samahy MA, Yang H, Wan YJ, Meng FX, Xiao SH, Wang F, Lei ZH
Theriogenology 2019 Mar 1;126:239-248
Theriogenology 2019 Mar 1;126:239-248
Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis.
Wang P, Geng J, Gao J, Zhao H, Li J, Shi Y, Yang B, Xiao C, Linghu Y, Sun X, Chen X, Hong L, Qin F, Li X, Yu JS, You H, Yuan Z, Zhou D, Johnson RL, Chen L
Nature communications 2019 Feb 14;10(1):755
Nature communications 2019 Feb 14;10(1):755
Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation.
Li W, Yue F, Dai Y, Shi B, Xu G, Jiang X, Zhou X, Pfeifer GP, Liu L
Cell death and differentiation 2019 Aug;26(8):1379-1395
Cell death and differentiation 2019 Aug;26(8):1379-1395
REGγ deficiency suppresses tumor progression via stabilizing CK1ε in renal cell carcinoma.
Chen S, Wang Q, Wang L, Chen H, Gao X, Gong D, Ma J, Kubra S, Yao X, Li X, Li L, Zhai W, Zheng J
Cell death & disease 2018 May 24;9(6):627
Cell death & disease 2018 May 24;9(6):627
Energy restriction affect liver development in Hu sheep ram lambs through Hippo signaling pathway.
Zhang TT, Zhang GM, Jin YH, Guo YX, Wang Z, Fan YX, El-Samahy MA, Wang F
Tissue & cell 2017 Oct;49(5):603-611
Tissue & cell 2017 Oct;49(5):603-611
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Li L, Fang R, Liu B, Shi H, Wang Y, Zhang W, Zhang X, Ye L
Oncogene 2016 Aug 4;35(31):4048-57
Oncogene 2016 Aug 4;35(31):4048-57
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22245-1-AP(STK4 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The STK4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human STK4. This antibody recognizes human,mouse,rat antigen. The STK4 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 22245-1-AP(STK4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 22245-1-AP(STK4 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue