RA0710

antibody from Oursmab

Targeting: TACSTD2 EGP-1, GA733-1, M1S1, TROP2

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0710

Provider

Oursmab

Product name

Sacituzumab (Biosimilar Reference Antibody) (TACSTD2)

Antibody type

Monoclonal

Description

Sacituzumab is an antibody-drug conjugate (ADC) targeting Trop-2 (trophoblast cell surface antigen 2), a transmembrane glycoprotein overexpressed in many epithelial cancers. It is linked to the cytotoxic payload SN-38 (a topoisomerase I inhibitor). Upon binding to Trop-2, the ADC is internalized, releasing SN-38 to induce DNA damage and tumor cell death. It is approved for the treatment of metastatic triple-negative breast cancer and urothelial carcinoma.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.