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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 66076-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66076-1-Ig, RRID:AB_11182924
- Product name
- TTL antibody
- Antibody type
- Monoclonal
- Description
- TTL antibody (Cat. #66076-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2E5F8
- Vial size
- 20ul, 150ul
Submitted references Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depletion.
α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments.
The intersection of inflammation and DNA damage as a novel axis underlying the pathogenesis of autism spectrum disorders.
Efficient axonal transport of endolysosomes relies on the balanced ratio of microtubule tyrosination and detyrosination.
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.
Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.
Tubulin detyrosination promotes human trophoblast syncytium formation.
Dissecting the role of the tubulin code in mitosis.
Jhanji M, Bhan A, Arrowood C, Yakout DW, Shroff A, McManus D, Gifford H, Vacharasin J, Lizarraga SB, Nazarko TY, Mabb AM, Sajish M
IUBMB life 2025 Jun;77(6):e70030
IUBMB life 2025 Jun;77(6):e70030
α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments.
Girão H, Macário-Monteiro J, Figueiredo AC, Silva E Sousa R, Doria E, Demidov V, Osório H, Jacome A, Meraldi P, Grishchuk EL, Maiato H
Nature communications 2024 Nov 9;15(1):9720
Nature communications 2024 Nov 9;15(1):9720
The intersection of inflammation and DNA damage as a novel axis underlying the pathogenesis of autism spectrum disorders.
Jhanji M, Krall CL, Guevara A, Yoon B, Sajish M, Boccuto L, Lizarraga SB
bioRxiv : the preprint server for biology 2024 Dec 11;
bioRxiv : the preprint server for biology 2024 Dec 11;
Efficient axonal transport of endolysosomes relies on the balanced ratio of microtubule tyrosination and detyrosination.
Konietzny A, Han Y, Popp Y, van Bommel B, Sharma A, Delagrange P, Arbez N, Moutin MJ, Peris L, Mikhaylova M
Journal of cell science 2024 Apr 15;137(8)
Journal of cell science 2024 Apr 15;137(8)
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.
Almeida AC, Soares-de-Oliveira J, Drpic D, Cheeseman LP, Damas J, Lewin HA, Larkin DM, Aguiar P, Pereira AJ, Maiato H
Cell reports 2022 Apr 5;39(1):110610
Cell reports 2022 Apr 5;39(1):110610
Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.
Mishra A, Emamgholi F, Erlangga Z, Hartleben B, Unger K, Wolff K, Teichmann U, Kessel M, Woller N, Kühnel F, Dow LE, Manns MP, Vogel A, Lowe SW, Saborowski A, Saborowski M
Carcinogenesis 2020 May 14;41(3):334-344
Carcinogenesis 2020 May 14;41(3):334-344
Tubulin detyrosination promotes human trophoblast syncytium formation.
Wang R, Yu R, Zhu C, Lin HY, Lu X, Wang H
Journal of molecular cell biology 2019 Dec 23;11(11):967-978
Journal of molecular cell biology 2019 Dec 23;11(11):967-978
Dissecting the role of the tubulin code in mitosis.
Ferreira LT, Figueiredo AC, Orr B, Lopes D, Maiato H
Methods in cell biology 2018;144:33-74
Methods in cell biology 2018;144:33-74
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 66076-1-Ig(TTL antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 66076-1-Ig(TTL antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TTL antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human TTL. This antibody recognizes human antigen. The TTL antibody has been validated for the following applications: ELISA, WB, IHC analysis.
