Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 17049-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17049-1-AP, RRID:AB_2281011
- Product name
- LATS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LATS1 antibody (Cat. #17049-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway.
Folic Acid Alleviates High Glucose and Fat-Induced Pyroptosis via Inhibition of the Hippo Signal Pathway on H9C2 Cells.
Luteolin Ameliorates Experimental Pulmonary Arterial Hypertension via Suppressing Hippo-YAP/PI3K/AKT Signaling Pathway.
Tetramethylpyrazine Ameliorates Peritoneal Angiogenesis by Regulating VEGF/Hippo/YAP Signaling.
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid-liquid phase separation to promote oncogenic YAP signaling.
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
miR-582-5p Is a Tumor Suppressor microRNA Targeting the Hippo-YAP/TAZ Signaling Pathway in Non-Small Cell Lung Cancer.
Tadalafil enhances the therapeutic efficacy of BET inhibitors in hepatocellular carcinoma through activating Hippo pathway.
Effect of antenatal tetramethylpyrazine on lung development and YAP expression in rat model of experimental congenital diaphragmatic hernia.
CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways.
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
The crosstalk between AXL and YAP promotes tumor progression through STAT3 activation in head and neck squamous cell carcinoma.
Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling.
TRIB3 confers radiotherapy resistance in esophageal squamous cell carcinoma by stabilizing TAZ.
Alginate oligosaccharide attenuates α2,6-sialylation modification to inhibit prostate cancer cell growth via the Hippo/YAP pathway.
Expression of Hippo signaling pathway components in Hu sheep male reproductive tract and spermatozoa.
Heat-shock protein B1 upholds the cytoplasm reduced state to inhibit activation of the Hippo pathway in H9c2 cells.
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
Transforming growth factor-beta1 suppresses hepatocellular carcinoma proliferation via activation of Hippo signaling.
Knockdown of yes-associated protein inhibits proliferation and downregulates large tumor suppressor 1 expression in MHCC97H human hepatocellular carcinoma cells.
Fu Y, Wan P, Zhang J, Li X, Xing J, Zou Y, Wang K, Peng H, Zhu Q, Cao L, Zhai X
Frontiers in cell and developmental biology 2021;9:741060
Frontiers in cell and developmental biology 2021;9:741060
Folic Acid Alleviates High Glucose and Fat-Induced Pyroptosis via Inhibition of the Hippo Signal Pathway on H9C2 Cells.
Hong L, Zha Y, Wang C, Qiao S, An J
Frontiers in molecular biosciences 2021;8:698698
Frontiers in molecular biosciences 2021;8:698698
Luteolin Ameliorates Experimental Pulmonary Arterial Hypertension via Suppressing Hippo-YAP/PI3K/AKT Signaling Pathway.
Zuo W, Liu N, Zeng Y, Xiao Z, Wu K, Yang F, Li B, Song Q, Xiao Y, Liu Q
Frontiers in pharmacology 2021;12:663551
Frontiers in pharmacology 2021;12:663551
Tetramethylpyrazine Ameliorates Peritoneal Angiogenesis by Regulating VEGF/Hippo/YAP Signaling.
Zhu X, Shan Y, Yu M, Shi J, Tang L, Cao H, Sheng M
Frontiers in pharmacology 2021;12:649581
Frontiers in pharmacology 2021;12:649581
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid-liquid phase separation to promote oncogenic YAP signaling.
Li RH, Tian T, Ge QW, He XY, Shi CY, Li JH, Zhang Z, Liu FZ, Sang LJ, Yang ZZ, Liu YZ, Xiong Y, Yan Q, Li X, Ju HQ, Liu J, Wang LJ, Shao JZ, Wang W, Zhou T, Lin A
Cell research 2021 Oct;31(10):1088-1105
Cell research 2021 Oct;31(10):1088-1105
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
Xu D, Chen PP, Zheng PQ, Yin F, Cheng Q, Zhou ZL, Xie HY, Li JY, Ni JY, Wang YZ, Chen SJ, Zhou L, Wang XX, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
miR-582-5p Is a Tumor Suppressor microRNA Targeting the Hippo-YAP/TAZ Signaling Pathway in Non-Small Cell Lung Cancer.
Zhu B, V M, Finch-Edmondson M, Lee Y, Wan Y, Sudol M, DasGupta R
Cancers 2021 Feb 11;13(4)
Cancers 2021 Feb 11;13(4)
Tadalafil enhances the therapeutic efficacy of BET inhibitors in hepatocellular carcinoma through activating Hippo pathway.
Kong D, Jiang Y, Miao X, Wu Z, Liu H, Gong W
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166267
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166267
Effect of antenatal tetramethylpyrazine on lung development and YAP expression in rat model of experimental congenital diaphragmatic hernia.
Liao J, Liu W, Zhang L, Li Q, Hou F, Zou P
International journal of clinical and experimental pathology 2020;13(1):81-88
International journal of clinical and experimental pathology 2020;13(1):81-88
CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways.
Chen L, Long X, Duan S, Liu X, Chen J, Lan J, Liu X, Huang W, Geng J, Zhou J
Theranostics 2020;10(24):11063-11079
Theranostics 2020;10(24):11063-11079
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
Zheng YW, Li ZH, Lei L, Liu CC, Wang Z, Fei LR, Yang MQ, Huang WJ, Xu HT
Frontiers in oncology 2020;10:180
Frontiers in oncology 2020;10:180
The crosstalk between AXL and YAP promotes tumor progression through STAT3 activation in head and neck squamous cell carcinoma.
Li J, Shi C, Zhou R, Han Y, Xu S, Ma H, Zhang Z
Cancer science 2020 Sep;111(9):3222-3235
Cancer science 2020 Sep;111(9):3222-3235
Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling.
Chen Z, Li S, Mo J, Hawley E, Wang Y, He Y, Brosseau JP, Shipman T, Clapp DW, Carroll TJ, Le LQ
JCI insight 2020 Oct 15;5(20)
JCI insight 2020 Oct 15;5(20)
TRIB3 confers radiotherapy resistance in esophageal squamous cell carcinoma by stabilizing TAZ.
Zhou S, Liu S, Lin C, Li Y, Ye L, Wu X, Jian Y, Dai Y, Ouyang Y, Zhao L, Liu M, Song L, Xi M
Oncogene 2020 Apr;39(18):3710-3725
Oncogene 2020 Apr;39(18):3710-3725
Alginate oligosaccharide attenuates α2,6-sialylation modification to inhibit prostate cancer cell growth via the Hippo/YAP pathway.
Han Y, Zhang L, Yu X, Wang S, Xu C, Yin H, Wang S
Cell death & disease 2019 May 10;10(5):374
Cell death & disease 2019 May 10;10(5):374
Expression of Hippo signaling pathway components in Hu sheep male reproductive tract and spermatozoa.
Zhang GM, Zhang TT, An SY, El-Samahy MA, Yang H, Wan YJ, Meng FX, Xiao SH, Wang F, Lei ZH
Theriogenology 2019 Mar 1;126:239-248
Theriogenology 2019 Mar 1;126:239-248
Heat-shock protein B1 upholds the cytoplasm reduced state to inhibit activation of the Hippo pathway in H9c2 cells.
Liu X, Liu K, Li C, Cai J, Huang L, Chen H, Wang H, Zou J, Liu M, Wang K, Tan S, Zhang H
Journal of cellular physiology 2019 Apr;234(4):5117-5133
Journal of cellular physiology 2019 Apr;234(4):5117-5133
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
Li M, Chen J, Yu X, Xu S, Li D, Zheng Q, Yin Y
Cells 2019 Apr 17;8(4)
Cells 2019 Apr 17;8(4)
Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
Zhang X, Li Y, Ma Y, Yang L, Wang T, Meng X, Zong Z, Sun X, Hua X, Li H
Journal of experimental & clinical cancer research : CR 2018 Sep 4;37(1):216
Journal of experimental & clinical cancer research : CR 2018 Sep 4;37(1):216
Transforming growth factor-beta1 suppresses hepatocellular carcinoma proliferation via activation of Hippo signaling.
Zhang X, Fan Q, Li Y, Yang Z, Yang L, Zong Z, Wang B, Meng X, Li Q, Liu J, Li H
Oncotarget 2017 May 2;8(18):29785-29794
Oncotarget 2017 May 2;8(18):29785-29794
Knockdown of yes-associated protein inhibits proliferation and downregulates large tumor suppressor 1 expression in MHCC97H human hepatocellular carcinoma cells.
Wang C, Zhu ZM, Liu CL, He XJ, Zhang HY, Dong JH
Molecular medicine reports 2015 Jun;11(6):4101-8
Molecular medicine reports 2015 Jun;11(6):4101-8
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 17049-1-AP(LATS1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LATS1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LATS1. This antibody recognizes human,mouse,rat antigen. The LATS1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.