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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Western blot [2]
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- Product number
- NB200-197 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB200-197, RRID:AB_10003247
- Product name
- Rabbit Polyclonal LATS1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.02 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development.
Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity.
Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.
A crucial role of WW45 in developing epithelial tissues in the mouse.
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway.
Huang JM, Nagatomo I, Suzuki E, Mizuno T, Kumagai T, Berezov A, Zhang H, Karlan B, Greene MI, Wang Q
Oncogene 2013 Apr 25;32(17):2220-9
Oncogene 2013 Apr 25;32(17):2220-9
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development.
Mao Y, Mulvaney J, Zakaria S, Yu T, Morgan KM, Allen S, Basson MA, Francis-West P, Irvine KD
Development (Cambridge, England) 2011 Mar;138(5):947-57
Development (Cambridge, England) 2011 Mar;138(5):947-57
Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity.
Salah Z, Melino G, Aqeilan RI
Cancer research 2011 Mar 1;71(5):2010-20
Cancer research 2011 Mar 1;71(5):2010-20
Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.
Oh S, Lee D, Kim T, Kim TS, Oh HJ, Hwang CY, Kong YY, Kwon KS, Lim DS
Molecular and cellular biology 2009 Dec;29(23):6309-20
Molecular and cellular biology 2009 Dec;29(23):6309-20
A crucial role of WW45 in developing epithelial tissues in the mouse.
Lee JH, Kim TS, Yang TH, Koo BK, Oh SP, Lee KP, Oh HJ, Lee SH, Kong YY, Kim JM, Lim DS
The EMBO journal 2008 Apr 23;27(8):1231-42
The EMBO journal 2008 Apr 23;27(8):1231-42
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway.
Zhang J, Smolen GA, Haber DA
Cancer research 2008 Apr 15;68(8):2789-94
Cancer research 2008 Apr 15;68(8):2789-94
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LATS1 Antibody [NB200-197] - Detection of mouse LATS1 by western blot. Samples: Whole cell lysate (50 µg) from CT26.WT and TCMK-1 cells. Antibodies: Affinity purified rabbit anti-LATS1 antibody NB200-197 used for WB at 0.2 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LATS1 Antibody [NB200-197] - Detection of Human LATS1 on HeLa whole cell lysate using NB200-197. LATS1 was also immunoprecipitated with another LATS1 antibody and NB200-198 using 3 mcg/mg lysate.
