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- References [21]
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- Product number
- 12423-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12423-1-AP, RRID:AB_2286212
- Product name
- SLC20A1 antibody
- Antibody type
- Polyclonal
- Description
- SLC20A1 antibody (Cat. #12423-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Development of a severe rat refeeding syndrome model and mathematical modeling of the associated hypophosphatemia.
SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production.
Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma.
SGK3 promotes vascular calcification via Pit-1 in chronic kidney disease.
Uropathogenic Escherichia coli infection: innate immune disorder, bladder damage, and Tailin Fang II.
Correlating Material Properties to Osteoprotegerin Expression on Nanoparticulate Mineralized Collagen Glycosaminoglycan Scaffolds.
Sodium-dependent phosphate transporter PiT1/SLC20A1 as the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formation.
Zinc Ameliorates High Pi and Ca-Mediated Osteogenic Differentiation of Mesenchymal Stem Cells.
Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8.
Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability.
SLC20A1 is a prospective prognostic and therapy response predictive biomarker in head and neck squamous cell carcinoma.
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
High sodium promotes the secretion and synthesis of PTH through PiT-1-IKKβ pathway in parathyroid gland in vitro.
Modulating Temporospatial Phosphate Equilibrium by Nanoparticulate Mineralized Collagen Materials Induces Osteogenesis via PiT-1 and PiT-2.
Bone-derived PDGF-BB drives brain vascular calcification in male mice.
Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells.
Iron Sucrose: A Double-Edged Sword in High Phosphate Media-Induced Vascular Calcification.
SLC20A1 Is Involved in Urinary Tract and Urorectal Development.
Oxidative stress by Ca(2+) overload is critical for phosphate-induced vascular calcification.
Phosphate (P(i))-regulated heterodimerization of the high-affinity sodium-dependent P(i) transporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular P(i) sensing independently of P(i) uptake.
Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion.
Kato H, Yamaoka I, Kubota H
NPJ systems biology and applications 2026 Feb 5;12(1)
NPJ systems biology and applications 2026 Feb 5;12(1)
SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production.
Nogueira RJ, Rodrigues AF, Mestre DA, Coroadinha AS
Molecular therapy. Methods & clinical development 2025 Dec 11;33(4):101619
Molecular therapy. Methods & clinical development 2025 Dec 11;33(4):101619
Lactobacillus acidophilus potentiates oncolytic virotherapy through modulating gut microbiota homeostasis in hepatocellular carcinoma.
Zhang J, Yang J, Luo J, Wu W, Luo H, Wei W, Lyu H, Wang Y, Yi H, Zhang Y, Fan Z, Lyu H, Kanakaveti VP, Qin B, Yuan P, Yang R, Zhang H, Zuo T, Felsher DW, Lee MH, Li K
Nature communications 2025 Apr 7;16(1):3315
Nature communications 2025 Apr 7;16(1):3315
SGK3 promotes vascular calcification via Pit-1 in chronic kidney disease.
Dong QQ, Tu YC, Gao P, Liao QQ, Zhou P, Zhang H, Shu HP, Sun LL, Feng L, Yao LJ
Theranostics 2024;14(2):861-878
Theranostics 2024;14(2):861-878
Uropathogenic Escherichia coli infection: innate immune disorder, bladder damage, and Tailin Fang II.
Li ZP, Li J, Li TL, Song ZY, Gong XZ
Frontiers in cellular and infection microbiology 2024;14:1322119
Frontiers in cellular and infection microbiology 2024;14:1322119
Correlating Material Properties to Osteoprotegerin Expression on Nanoparticulate Mineralized Collagen Glycosaminoglycan Scaffolds.
Chen W, Bedar M, Zhou Q, Ren X, Kang Y, Huang KX, Rubino G, Kolliopoulos V, Moghadam S, Cascavita CT, Taylor JM, Chevalier JM, Harley BAC, Lee JC
Advanced healthcare materials 2024 Oct;13(26):e2401037
Advanced healthcare materials 2024 Oct;13(26):e2401037
Sodium-dependent phosphate transporter PiT1/SLC20A1 as the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formation.
Mousseau G, Préault N, Souquere S, Bireau C, Cassonnet P, Bacquin A, Beck L, Pierron G, Jacob Y, Dupressoir A, Heidmann T
Journal of virology 2024 Oct 22;98(10):e0091524
Journal of virology 2024 Oct 22;98(10):e0091524
Zinc Ameliorates High Pi and Ca-Mediated Osteogenic Differentiation of Mesenchymal Stem Cells.
Balogh E, Tóth A, Csiki DM, Jeney V
Nutrients 2024 Nov 23;16(23)
Nutrients 2024 Nov 23;16(23)
Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8.
Li X, Kirkpatrick RB, Wang X, Tucker CJ, Shukla A, Jessen HJ, Wang H, Shears SB, Gu C
Cell reports 2024 Jun 25;43(6):114316
Cell reports 2024 Jun 25;43(6):114316
Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability.
Ramos-Brossier M, Romeo-Guitart D, Lanté F, Boitez V, Mailliet F, Saha S, Rivagorda M, Siopi E, Nemazanyy I, Leroy C, Moriceau S, Beck-Cormier S, Codogno P, Buisson A, Beck L, Friedlander G, Oury F
Cell death & disease 2024 Jan 9;15(1):20
Cell death & disease 2024 Jan 9;15(1):20
SLC20A1 is a prospective prognostic and therapy response predictive biomarker in head and neck squamous cell carcinoma.
Qian X, Jin M, Bei Y, Zhou C, Fang S, Liu K
Aging 2024 Feb 26;16(5):4423-4444
Aging 2024 Feb 26;16(5):4423-4444
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
Watson DC, Bayik D, Storevik S, Moreino SS, Sprowls SA, Han J, Augustsson MT, Lauko A, Sravya P, Røsland GV, Troike K, Tronstad KJ, Wang S, Sarnow K, Kay K, Lunavat TR, Silver DJ, Dayal S, Joseph JV, Mulkearns-Hubert E, Ystaas LAR, Deshpande G, Guyon J, Zhou Y, Magaut CR, Seder J, Neises L, Williford SE, Meiser J, Scott AJ, Sajjakulnukit P, Mears JA, Bjerkvig R, Chakraborty A, Daubon T, Cheng F, Lyssiotis CA, Wahl DR, Hjelmeland AB, Hossain JA, Miletic H, Lathia JD
Nature cancer 2023 May;4(5):648-664
Nature cancer 2023 May;4(5):648-664
High sodium promotes the secretion and synthesis of PTH through PiT-1-IKKβ pathway in parathyroid gland in vitro.
Shen A, Wang Y, Ye G, Mao J, Zhang Q, Chen J
Clinical science (London, England : 1979) 2023 Jun 28;137(12):947-962
Clinical science (London, England : 1979) 2023 Jun 28;137(12):947-962
Modulating Temporospatial Phosphate Equilibrium by Nanoparticulate Mineralized Collagen Materials Induces Osteogenesis via PiT-1 and PiT-2.
Ren X, Zhou Q, Bedar M, Foulad D, Huang KX, Dejam D, Dahan NJ, Kolliopoulos V, Harley BAC, Lee JC
Advanced healthcare materials 2023 Jul;12(17):e2202750
Advanced healthcare materials 2023 Jul;12(17):e2202750
Bone-derived PDGF-BB drives brain vascular calcification in male mice.
Wang J, Fang CL, Noller K, Wei Z, Liu G, Shen K, Song K, Cao X, Wan M
The Journal of clinical investigation 2023 Dec 1;133(23)
The Journal of clinical investigation 2023 Dec 1;133(23)
Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells.
Zhang M, Li T, Tu Z, Zhang Y, Wang X, Zang D, Xu D, Feng Y, He F, Ni M, Wang D, Zhou H
International urology and nephrology 2022 Oct;54(10):2719-2731
International urology and nephrology 2022 Oct;54(10):2719-2731
Iron Sucrose: A Double-Edged Sword in High Phosphate Media-Induced Vascular Calcification.
Wang P, Guo C, Pan H, Chen W, Peng D
Calcified tissue international 2021 Jun;108(6):798-807
Calcified tissue international 2021 Jun;108(6):798-807
SLC20A1 Is Involved in Urinary Tract and Urorectal Development.
Rieke JM, Zhang R, Braun D, Yilmaz Ö, Japp AS, Lopes FM, Pleschka M, Hilger AC, Schneider S, Newman WG, Beaman GM, Nordenskjöld A, Ebert AK, Promm M, Rösch WH, Stein R, Hirsch K, Schäfer FM, Schmiedeke E, Boemers TM, Lacher M, Kluth D, Gosemann JH, Anderberg M, Barker G, Holmdahl G, Läckgren G, Keene D, Cervellione RM, Giorgio E, Di Grazia M, Feitz WFJ, Marcelis CLM, Van Rooij IALM, Bökenkamp A, Beckers GMA, Keegan CE, Sharma A, Dakal TC, Wittler L, Grote P, Zwink N, Jenetzky E, Brusco A, Thiele H, Ludwig M, Schweizer U, Woolf AS, Odermatt B, Reutter H
Frontiers in cell and developmental biology 2020;8:567
Frontiers in cell and developmental biology 2020;8:567
Oxidative stress by Ca(2+) overload is critical for phosphate-induced vascular calcification.
Nguyen NT, Nguyen TT, Da Ly D, Xia JB, Qi XF, Lee IK, Cha SK, Park KS
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1302-H1312
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1302-H1312
Phosphate (P(i))-regulated heterodimerization of the high-affinity sodium-dependent P(i) transporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular P(i) sensing independently of P(i) uptake.
Bon N, Couasnay G, Bourgine A, Sourice S, Beck-Cormier S, Guicheux J, Beck L
The Journal of biological chemistry 2018 Feb 9;293(6):2102-2114
The Journal of biological chemistry 2018 Feb 9;293(6):2102-2114
Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion.
Nguyen TT, Quan X, Xu S, Das R, Cha SK, Kong ID, Shong M, Wollheim CB, Park KS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Dec;30(12):3979-3988
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Dec;30(12):3979-3988
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 12423-1-AP(SLC20A1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lymphoma using 12423-1-AP(SLC20A1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SLC20A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SLC20A1. This antibody recognizes human, mouse, rat antigen. The SLC20A1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
