BS60298

antibody from Bioworld Technology, Inc
Targeting: IL37 FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7
Provider product page for BS60298

Antibody data

Product number
BS60298 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IL37 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human IL37.
Description
IL-1 (Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors, NF°ÙB and AP-1, thereby promoting host response to injury or infection. The IL-1 superfamily is comprised of several ligands and receptors. IL-1F7, also known as IL-1šø, IL-1 homolog 4 (IL-1H4) or IL-1 related protein 1 (IL-1rp1), is a secreted ligand belonging to this superfamily. It is expressed in the cytoplasm of peripheral monocytic cells localizing to the inner surface of the plasma membrane and surrounding the nuclear membrane suggesting that IL-1F7 may play a role in immune regulation. Five isoforms exist for this protein due to alternative splicing and they are designated IL-1F7a through IL-1F7e. Isoform a has a distinct N-terminus while isoforms c-d are truncated. Isoform b is the mature functional isoform that binds to the IL-18RÏ«-chain and the IL-18 binding protein (IL-18BP) acting as an IL-18 antagonist. IL-1F7 is closely related to IL-1ra, sharing 36% sequence identity.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IL37 protein structure - BS60298 shown in red.