APR06852G
antibody from Leading Biology
Targeting: IL36G
IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- APR06852G - Provider product page
- Provider
- Leading Biology
- Product name
- IL-36G Antibody
- Antibody type
- Polyclonal
- Description
- IL-36G is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36G is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36B, IL-36G requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). IL-36G expression is stimulated by interferon-gamma, tumor necrosis factor-alpha and interleukin 1 (4). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (5).
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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