Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA029041 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA029041, RRID:AB_2672880
- Product name
- Anti-MTHFD1L
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MTHFD1L, Gene description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like, Alternative Gene Names: DKFZP586G1517, FLJ21145, FTHFSDC1, Validated applications: IHC, WB, Uniprot ID: Q6UB35, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mitochondrial translation requires folate-dependent tRNA methylation
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma.
Morscher R, Ducker G, Li S, Mayer J, Gitai Z, Sperl W, Rabinowitz J
Nature 2018;554(7690):128-132
Nature 2018;554(7690):128-132
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma.
Lee D, Xu IM, Chiu DK, Lai RK, Tse AP, Lan Li L, Law CT, Tsang FH, Wei LL, Chan CY, Wong CM, Ng IO, Wong CC
The Journal of clinical investigation 2017 May 1;127(5):1856-1872
The Journal of clinical investigation 2017 May 1;127(5):1856-1872
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human placenta and skeletal muscle tissues using HPA029041 antibody. Corresponding MTHFD1L RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol