Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
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- Product number
- 17894-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17894-1-AP, RRID:AB_2163630
- Product name
- VPS15 antibody
- Antibody type
- Polyclonal
- Description
- VPS15 antibody (Cat. #17894-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging.
HSPA8 regulates anti-bacterial autophagy through liquid-liquid phase separation.
Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Targeting AR-Beclin 1 complex-modulated growth factor signaling increases the antiandrogen Enzalutamide sensitivity to better suppress the castration-resistant prostate cancer growth.
Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.
Protective effects of p-nitro caffeic acid phenethyl ester on acute myocardial ischemia-reperfusion injury in rats.
Guo R, Liu J, Min X, Zeng W, Shan B, Zhang M, He Z, Zhang Y, He K, Yuan J, Xu D
Nature structural & molecular biology 2024 Feb;31(2):232-245
Nature structural & molecular biology 2024 Feb;31(2):232-245
HSPA8 regulates anti-bacterial autophagy through liquid-liquid phase separation.
Miao C, Zhang Y, Yu M, Wei Y, Dong C, Pei G, Xiao Y, Yang J, Yao Z, Wang Q
Autophagy 2023 Oct;19(10):2702-2718
Autophagy 2023 Oct;19(10):2702-2718
Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
Kang Y, Yin S, Liu J, Jiang Y, Huang Z, Chen L, Shao L
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
Journal of hazardous materials 2022 Feb 15;424(Pt D):127660
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
Tremel S, Ohashi Y, Morado DR, Bertram J, Perisic O, Brandt LTL, von Wrisberg MK, Chen ZA, Maslen SL, Kovtun O, Skehel M, Rappsilber J, Lang K, Munro S, Briggs JAG, Williams RL
Nature communications 2021 Mar 10;12(1):1564
Nature communications 2021 Mar 10;12(1):1564
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.
Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, Chen Y, Liu A, Wu Q, Sun L, Xu F, Hu F, Chen L, Luo X, Feng Y, Huang S, Hu J, Wang G
Nature communications 2021 Jun 15;12(1):3651
Nature communications 2021 Jun 15;12(1):3651
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Targeting AR-Beclin 1 complex-modulated growth factor signaling increases the antiandrogen Enzalutamide sensitivity to better suppress the castration-resistant prostate cancer growth.
Zhang M, Sun Y, Meng J, Zhang L, Liang C, Chang C
Cancer letters 2019 Feb 1;442:483-490
Cancer letters 2019 Feb 1;442:483-490
Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.
Gstrein T, Edwards A, Přistoupilová A, Leca I, Breuss M, Pilat-Carotta S, Hansen AH, Tripathy R, Traunbauer AK, Hochstoeger T, Rosoklija G, Repic M, Landler L, Stránecký V, Dürnberger G, Keane TM, Zuber J, Adams DJ, Flint J, Honzik T, Gut M, Beltran S, Mechtler K, Sherr E, Kmoch S, Gut I, Keays DA
Nature neuroscience 2018 Feb;21(2):207-217
Nature neuroscience 2018 Feb;21(2):207-217
Protective effects of p-nitro caffeic acid phenethyl ester on acute myocardial ischemia-reperfusion injury in rats.
DU Q, Hao C, Gou J, Li X, Zou K, He X, Li Z
Experimental and therapeutic medicine 2016 Apr;11(4):1433-1440
Experimental and therapeutic medicine 2016 Apr;11(4):1433-1440
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 17894-1-AP(PIK3R4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using PIK3R4 antibody 17894-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line