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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
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- Product number
- NBP1-30463 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-30463, RRID:AB_2163632
- Product name
- Rabbit Polyclonal PIK3R4 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Zebrafish
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease.
Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.
Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase.
A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi.
Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis.
Connexins modulate autophagosome biogenesis.
Functional interaction between autophagy and ciliogenesis.
Franco-Iborra S, Plaza-Zabala A, Montpeyo M, Sebastian D, Vila M, Martinez-Vicente M
Autophagy 2021 Mar;17(3):672-689
Autophagy 2021 Mar;17(3):672-689
Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.
Gstrein T, Edwards A, Přistoupilová A, Leca I, Breuss M, Pilat-Carotta S, Hansen AH, Tripathy R, Traunbauer AK, Hochstoeger T, Rosoklija G, Repic M, Landler L, Stránecký V, Dürnberger G, Keane TM, Zuber J, Adams DJ, Flint J, Honzik T, Gut M, Beltran S, Mechtler K, Sherr E, Kmoch S, Gut I, Keays DA
Nature neuroscience 2018 Feb;21(2):207-217
Nature neuroscience 2018 Feb;21(2):207-217
Class III PI3K Positively Regulates Platelet Activation and Thrombosis via PI(3)P-Directed Function of NADPH Oxidase.
Liu Y, Hu M, Luo D, Yue M, Wang S, Chen X, Zhou Y, Wang Y, Cai Y, Hu X, Ke Y, Yang Z, Hu H
Arteriosclerosis, thrombosis, and vascular biology 2017 Nov;37(11):2075-2086
Arteriosclerosis, thrombosis, and vascular biology 2017 Nov;37(11):2075-2086
A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi.
Stoetzel C, Bär S, De Craene JO, Scheidecker S, Etard C, Chicher J, Reck JR, Perrault I, Geoffroy V, Chennen K, Strähle U, Hammann P, Friant S, Dollfus H
Nature communications 2016 Nov 24;7:13586
Nature communications 2016 Nov 24;7:13586
Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis.
Kaushik S, Cuervo AM
Nature cell biology 2015 Jun;17(6):759-70
Nature cell biology 2015 Jun;17(6):759-70
Connexins modulate autophagosome biogenesis.
Bejarano E, Yuste A, Patel B, Stout RF Jr, Spray DC, Cuervo AM
Nature cell biology 2014 May;16(5):401-14
Nature cell biology 2014 May;16(5):401-14
Functional interaction between autophagy and ciliogenesis.
Pampliega O, Orhon I, Patel B, Sridhar S, Díaz-Carretero A, Beau I, Codogno P, Satir BH, Satir P, Cuervo AM
Nature 2013 Oct 10;502(7470):194-200
Nature 2013 Oct 10;502(7470):194-200
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PIK3R4 Antibody [NBP1-30463] - Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells. Vps15 was also immunoprecipitated by rabbit anti-Vps15 antibody NBP1-30462.
