Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3912 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3912, RRID:AB_1581741
- Product name
- USP1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of USP1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Human and mouse proteases: a comparative genomic approach.
Deubiquitinating enzymes: a new class of biological regulators.
Identification and chromosomal assignment of USP1, a novel gene encoding a human ubiquitin-specific protease.
Puente XS, Sánchez LM, Overall CM, López-Otín C
Nature reviews. Genetics 2003 Jul;4(7):544-58
Nature reviews. Genetics 2003 Jul;4(7):544-58
Deubiquitinating enzymes: a new class of biological regulators.
D'Andrea A, Pellman D
Critical reviews in biochemistry and molecular biology 1998;33(5):337-52
Critical reviews in biochemistry and molecular biology 1998;33(5):337-52
Identification and chromosomal assignment of USP1, a novel gene encoding a human ubiquitin-specific protease.
Fujiwara T, Saito A, Suzuki M, Shinomiya H, Suzuki T, Takahashi E, Tanigami A, Ichiyama A, Chung CH, Nakamura Y, Tanaka K
Genomics 1998 Nov 15;54(1):155-8
Genomics 1998 Nov 15;54(1):155-8
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of USP1 polyclonal antibody (Cat # PAB3912) in HepG2 cell line lysate (35 ug/lane). USP1 (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with USP1 polyclonal antibody (Cat # PAB3912) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)