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- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 66069-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66069-1-Ig, RRID:AB_11043340
- Product name
- USP1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated USP1 antibody (Cat. #66069-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1C10H6
- Vial size
- 20ul, 150ul
Submitted references USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
USP5 inhibition enables potential therapy for t(8;21) AML through ubiquitin-mediated AML1-ETO degradation in patient-derived xenografts.
Ubiquitin-specific protease 1 facilitates hepatocellular carcinoma progression by modulating mitochondrial fission and metabolic reprogramming via cyclin-dependent kinase 5 stabilization.
Ubiquitin-specific proteinase 1 stabilizes PRRSV nonstructural protein Nsp1β to promote viral replication by regulating K48 ubiquitination.
Chen Z, Sun C, Wang Y, Duan X, Ma H, Zhou X, Chen S, Peng P
iScience 2026 Mar 20;29(3):114927
iScience 2026 Mar 20;29(3):114927
USP5 inhibition enables potential therapy for t(8;21) AML through ubiquitin-mediated AML1-ETO degradation in patient-derived xenografts.
Ma L, Zhang K, Zhang Z, Wang C, Ma M, Liu Y, Zhao Y, Gong Z, Liu N, Wei M, Liu X, Zhou J, Liu S, Yang C, Yang G
Science translational medicine 2025 Sep 24;17(817):eadt9100
Science translational medicine 2025 Sep 24;17(817):eadt9100
Ubiquitin-specific protease 1 facilitates hepatocellular carcinoma progression by modulating mitochondrial fission and metabolic reprogramming via cyclin-dependent kinase 5 stabilization.
Bian S, Ni W, Zhou L, Tong Y, Dai C, Zhao X, Qiang Y, Gao J, Xiao Y, Liu W, Chen C, Lin S, Gong J, Zhao S, Chen Y, Lin Z, Liu D, Zhao H, Zheng W
Cell death and differentiation 2024 Sep;31(9):1202-1218
Cell death and differentiation 2024 Sep;31(9):1202-1218
Ubiquitin-specific proteinase 1 stabilizes PRRSV nonstructural protein Nsp1β to promote viral replication by regulating K48 ubiquitination.
Zhai Y, Du Y, Yuan H, Fan S, Chen X, Wang J, He W, Han S, Zhang Y, Hu M, Zhang G, Kong Z, Wan B
Journal of virology 2024 Mar 19;98(3):e0168623
Journal of virology 2024 Mar 19;98(3):e0168623
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 66069-1-Ig(USP1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 66069-1-Ig(USP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP1 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human USP1. This antibody recognizes human antigen. The USP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
