abx004477

antibody from Abbexa

Targeting: ITGB3BP CENPR, HSU37139, NRIF3, TAP20

Western blot (Recommended by provider)

Antibody Data

Product number

abx004477

Provider

Abbexa

Product name

Centromere Protein R (ITGB3BP) Antibody

Antibody type

Polyclonal

Description

ITGB3BP Antibody is a Rabbit Polyclonal antibody against ITGB3BP. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.