Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10872-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10872-1-AP, RRID:AB_2247034
- Product name
- FBXO5 antibody
- Antibody type
- Polyclonal
- Description
- FBXO5 antibody (Cat. #10872-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication.
FBXO5 drives hepatocellular carcinoma progression and is a target for tea polyphenol-mediated inhibition.
Integrative analysis identifies FBXO5 as a critical mediator of CRPC progression and bone metastatic potential.
Downregulation of Splicing Factor PTBP1 Curtails FBXO5 Expression to Promote Cellular Senescence in Lung Adenocarcinoma.
Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma.
Expression significance of Emi1, UBCH10 and CyclinB1 in esophageal squamous cell carcinoma.
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Exploring the role of FBXO5 in gastric cancer.
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
CRL4(AMBRA1) is a master regulator of D-type cyclins.
An upstream open reading frame regulates vasculogenic mimicry of glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 pathway.
Identification of aberrantly expressed F-box proteins in squamous-cell lung carcinoma.
Matsuhashi K, Ito KK, Nagai K, Sanada A, Watanabe K, Takumi K, Toyoda A, Fukuyama M, Yamamoto S, Chinen T, Stewart GS, Hata S, Kitagawa D
Nature communications 2025 Sep 8;16(1):7799
Nature communications 2025 Sep 8;16(1):7799
FBXO5 drives hepatocellular carcinoma progression and is a target for tea polyphenol-mediated inhibition.
Wang X, Yang D, Wang J, Huang Z, Gao J, Xia J, Zhang Y, Ma J, Pan X
Translational cancer research 2025 Oct 31;14(10):7229-7244
Translational cancer research 2025 Oct 31;14(10):7229-7244
Integrative analysis identifies FBXO5 as a critical mediator of CRPC progression and bone metastatic potential.
Raut R, Srivastava D, Chakraborty AK, Bais MV, Mishra P, Misra A
Discover oncology 2025 Aug 7;16(1):1495
Discover oncology 2025 Aug 7;16(1):1495
Downregulation of Splicing Factor PTBP1 Curtails FBXO5 Expression to Promote Cellular Senescence in Lung Adenocarcinoma.
Li H, Sun X, Lv Y, Wei G, Ni T, Qin W, Jin H, Jia Q
Current issues in molecular biology 2024 Jul 19;46(7):7730-7744
Current issues in molecular biology 2024 Jul 19;46(7):7730-7744
Role of arbutin in the inhibition of FBXO5 in hepatocellular carcinoma.
Zhang S, Yao K, Pi Y, Yang S, Huang Z, Pan X, Li T
Discover oncology 2024 Dec 23;15(1):827
Discover oncology 2024 Dec 23;15(1):827
Expression significance of Emi1, UBCH10 and CyclinB1 in esophageal squamous cell carcinoma.
Li H, Yang C, Chen K, Sun M
Pathology oncology research : POR 2023;29:1611081
Pathology oncology research : POR 2023;29:1611081
DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.
Xu X, Chang CW, Li M, Omabe K, Le N, Chen YH, Liang F, Liu Y
Nature communications 2023 Mar 4;14(1):1233
Nature communications 2023 Mar 4;14(1):1233
Exploring the role of FBXO5 in gastric cancer.
Zhang J, Zhang G, Wang K, Cui F, Yang H, Jiao Z
Molecular and cellular probes 2023 Jun;69:101915
Molecular and cellular probes 2023 Jun;69:101915
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Wei P, Jiang J, Xiao M, Zeng M, Liu X, Zhao B, Chen F
Experimental cell research 2022 Mar 1;412(1):113009
Experimental cell research 2022 Mar 1;412(1):113009
CRL4(AMBRA1) is a master regulator of D-type cyclins.
Simoneschi D, Rona G, Zhou N, Jeong YT, Jiang S, Milletti G, Arbini AA, O'Sullivan A, Wang AA, Nithikasem S, Keegan S, Siu Y, Cianfanelli V, Maiani E, Nazio F, Cecconi F, Boccalatte F, Fenyƶ D, Jones DR, Busino L, Pagano M
Nature 2021 Apr;592(7856):789-793
Nature 2021 Apr;592(7856):789-793
An upstream open reading frame regulates vasculogenic mimicry of glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 pathway.
Wang M, Yang C, Liu X, Zheng J, Xue Y, Ruan X, Shen S, Wang D, Li Z, Cai H, Liu Y
Journal of cellular and molecular medicine 2020 Jun;24(11):6120-6136
Journal of cellular and molecular medicine 2020 Jun;24(11):6120-6136
Identification of aberrantly expressed F-box proteins in squamous-cell lung carcinoma.
Wang K, Qu X, Liu S, Yang X, Bie F, Wang Y, Huang C, Du J
Journal of cancer research and clinical oncology 2018 Aug;144(8):1509-1521
Journal of cancer research and clinical oncology 2018 Aug;144(8):1509-1521
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10872-1-AP(FBXO5 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The FBXO5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FBXO5. This antibody recognizes human, mouse, rat antigen. The FBXO5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.