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- References [14]
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- Product number
- 13747-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13747-1-AP, RRID:AB_2108058
- Product name
- GADD45A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GADD45A antibody (Cat. #13747-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Harmine inhibits pulmonary fibrosis through regulating DNA damage repair-related genes and activation of TP53-Gadd45α pathway.
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
TiO(2) Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion.
CircRNA_014511 affects the radiosensitivity of bone marrow mesenchymal stem cells by binding to miR-29b-2-5p.
Selective activation of tumor-suppressive MAPKP signaling pathway by triptonide effectively inhibits pancreatic cancer cell tumorigenicity and tumor growth.
Down-regulation of GADD45A enhances chemosensitivity in melanoma.
miR-124 and miR-9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C-GPM6A pathway.
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Overexpression of HP1γ is associated with poor prognosis in non-small cell lung cancer cell through promoting cell survival.
Gong Y, Wang J, Pan M, Zhao Y, Zhang H, Zhang F, Liu J, Yang J, Hu J
International immunopharmacology 2024 Sep 10;138:112542
International immunopharmacology 2024 Sep 10;138:112542
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Fan R, Wang S, Wu Y, Feng Y, Gao M, Cao Y, Ma X, Xie S, Wang C, Gao L, Wang Y, Dai F
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair.
Peng S, Sun Y, Luo Y, Ma S, Sun W, Tang G, Li S, Zhang N, Ren J, Xiao Y, Liu X, Zhang J, Gong Y, Xie C
International journal of biological sciences 2020;16(12):2145-2158
International journal of biological sciences 2020;16(12):2145-2158
TiO(2) Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal Administration in Rats.
Han B, Pei Z, Shi L, Wang Q, Li C, Zhang B, Su X, Zhang N, Zhou L, Zhao B, Niu Y, Zhang R
International journal of nanomedicine 2020;15:6279-6294
International journal of nanomedicine 2020;15:6279-6294
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Han N, Yuan F, Xian P, Liu N, Liu J, Zhang H, Zhang H, Yao K, Yuan G
OncoTargets and therapy 2019;12:7591-7599
OncoTargets and therapy 2019;12:7591-7599
Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion.
He GQ, Xu WM, Liao HJ, Jiang C, Li CQ, Zhang W
Neural regeneration research 2019 Nov;14(11):1977-1985
Neural regeneration research 2019 Nov;14(11):1977-1985
CircRNA_014511 affects the radiosensitivity of bone marrow mesenchymal stem cells by binding to miR-29b-2-5p.
Wang Y, Zhang J, Li J, Gui R, Nie X, Huang R
Bosnian journal of basic medical sciences 2019 May 20;19(2):155-163
Bosnian journal of basic medical sciences 2019 May 20;19(2):155-163
Selective activation of tumor-suppressive MAPKP signaling pathway by triptonide effectively inhibits pancreatic cancer cell tumorigenicity and tumor growth.
Zhang B, Meng M, Xiang S, Cao Z, Xu X, Zhao Z, Zhang T, Chen B, Yang P, Li Y, Zhou Q
Biochemical pharmacology 2019 Aug;166:70-81
Biochemical pharmacology 2019 Aug;166:70-81
Down-regulation of GADD45A enhances chemosensitivity in melanoma.
Liu J, Jiang G, Mao P, Zhang J, Zhang L, Liu L, Wang J, Owusu L, Ren B, Tang Y, Li W
Scientific reports 2018 Mar 7;8(1):4111
Scientific reports 2018 Mar 7;8(1):4111
miR-124 and miR-9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C-GPM6A pathway.
Gu X, Fu C, Lin L, Liu S, Su X, Li A, Wu Q, Jia C, Zhang P, Chen L, Zhu X, Wang X
Journal of cellular physiology 2018 Jan;233(1):673-687
Journal of cellular physiology 2018 Jan;233(1):673-687
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Yuan G, Chen X, Liu Z, Wei W, Shu Q, Abou-Hamdan H, Jiang L, Li X, Chen R, Désaubry L, Zhou F, Xie D
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
Cell research 2018 Aug;28(8):833-854
Cell research 2018 Aug;28(8):833-854
Overexpression of HP1γ is associated with poor prognosis in non-small cell lung cancer cell through promoting cell survival.
Zhou J, Bi H, Zhan P, Chang C, Xu C, Huang X, Yu L, Yao X, Yan J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Oct;35(10):9777-85
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Oct;35(10):9777-85
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GADD45A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GADD45A. This antibody recognizes human,mouse,rat antigen. The GADD45A antibody has been validated for the following applications: ELISA, WB analysis.
