Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 17939-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17939-1-AP, RRID:AB_2285290
- Product name
- RPE65 antibody
- Antibody type
- Polyclonal
- Description
- RPE65 antibody (Cat. #17939-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A Nucleic Acid-Based LYTAC Plus Platform to Simultaneously Mediate Disease-Driven Protein Downregulation.
Dasatinib Plus Quercetin Alleviates Choroid Neovascularization by Reducing the Cellular Senescence Burden in the RPE-Choroid.
CRISPR-cas9 screening identified lethal genes enriched in Hippo kinase pathway and of predictive significance in primary low-grade glioma.
Region-resolved multi-omics of the mouse eye.
Prph2 disease mutations lead to structural and functional defects in the RPE.
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4(-/-)/Bco2(-/-) double knockout mice.
The Construction of Retinal Pigment Epithelium Sheets with Enhanced Characteristics and Cilium Assembly Using iPS Conditioned Medium and Small Incision Lenticule Extraction Derived Lenticules.
Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal.
Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina.
Impaired Rhodopsin Generation in the Rat Model of Diabetic Retinopathy.
Huang Y, Zhou X, Zhang Y, Xie M, Wang F, Qin J, Ye H, Zhang H, Zhang C, Hong J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306248
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(13):e2306248
Dasatinib Plus Quercetin Alleviates Choroid Neovascularization by Reducing the Cellular Senescence Burden in the RPE-Choroid.
Wang Y, Tseng Y, Chen K, Chen K, Chen K, Huang Z, Mao Z, Li X
Investigative ophthalmology & visual science 2023 Sep 1;64(12):39
Investigative ophthalmology & visual science 2023 Sep 1;64(12):39
CRISPR-cas9 screening identified lethal genes enriched in Hippo kinase pathway and of predictive significance in primary low-grade glioma.
Mijiti M, Maimaiti A, Chen X, Tuersun M, Dilixiati M, Dilixiati Y, Zhu G, Wu H, Li Y, Turhon M, Abulaiti A, Maimaitiaili N, Yiming N, Kasimu M, Wang Y
Molecular medicine (Cambridge, Mass.) 2023 May 14;29(1):64
Molecular medicine (Cambridge, Mass.) 2023 May 14;29(1):64
Region-resolved multi-omics of the mouse eye.
Xiang H, Zhang B, Wang Y, Xu N, Zhang F, Luo R, Ji M, Ding C
Cell reports 2023 Feb 28;42(2):112121
Cell reports 2023 Feb 28;42(2):112121
Prph2 disease mutations lead to structural and functional defects in the RPE.
Tebbe L, Sakthivel H, Makia MS, Kakakhel M, Conley SM, Al-Ubaidi MR, Naash MI
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22284
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22284
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Ren X, Lv J, Wang N, Liu J, Gao C, Wu X, Yu Y, Teng Q, Dong W, Kong H, Kong L
Diabetes research and clinical practice 2022 Mar;185:109788
Diabetes research and clinical practice 2022 Mar;185:109788
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Liu C, Sun W, Zhu T, Shi S, Zhang J, Wang J, Gao F, Ou Q, Jin C, Li J, Xu JY, Zhang J, Tian H, Xu GT, Lu L
Redox biology 2022 Jun;52:102292
Redox biology 2022 Jun;52:102292
Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4(-/-)/Bco2(-/-) double knockout mice.
Arunkumar R, Gorusupudi A, Li B, Blount JD, Nwagbo U, Kim HJ, Sparrow JR, Bernstein PS
Experimental eye research 2021 Aug;209:108680
Experimental eye research 2021 Aug;209:108680
The Construction of Retinal Pigment Epithelium Sheets with Enhanced Characteristics and Cilium Assembly Using iPS Conditioned Medium and Small Incision Lenticule Extraction Derived Lenticules.
Gu J, Wang Y, Cui Z, Li H, Li S, Yang X, Yan X, Ding C, Tang S, Chen J
Acta biomaterialia 2019 Jul 1;92:115-131
Acta biomaterialia 2019 Jul 1;92:115-131
Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal.
Liao Y, Zhang H, He D, Wang Y, Cai B, Chen J, Ma J, Liu Z, Wu Y
Investigative ophthalmology & visual science 2019 Jul 1;60(8):3034-3045
Investigative ophthalmology & visual science 2019 Jul 1;60(8):3034-3045
Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina.
Gao Z, Liao Y, Chen C, Liao C, He D, Chen J, Ma J, Liu Z, Wu Y
The Journal of biological chemistry 2018 Sep 14;293(37):14507-14519
The Journal of biological chemistry 2018 Sep 14;293(37):14507-14519
Impaired Rhodopsin Generation in the Rat Model of Diabetic Retinopathy.
Malechka VV, Moiseyev G, Takahashi Y, Shin Y, Ma JX
The American journal of pathology 2017 Oct;187(10):2222-2231
The American journal of pathology 2017 Oct;187(10):2222-2231
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RPE65 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPE65. This antibody recognizes human,mouse,rat antigen. The RPE65 antibody has been validated for the following applications: ELISA, WB analysis.