Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- GTX103472 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX103472, RRID:AB_2037911
- Product name
- RPE65 antibody [N1C3]
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells.
Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium.
Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina.
Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase.
Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin.
Bulloj A, Maminishkis A, Mizui M, Finnemann SC
Molecular neurobiology 2018 May;55(5):4320-4332
Molecular neurobiology 2018 May;55(5):4320-4332
Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium.
Müller C, Charniga C, Temple S, Finnemann SC
Stem cell reports 2018 Mar 13;10(3):1075-1087
Stem cell reports 2018 Mar 13;10(3):1075-1087
Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina.
Ruggiero L, Connor MP, Chen J, Langen R, Finnemann SC
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):8145-8
Proceedings of the National Academy of Sciences of the United States of America 2012 May 22;109(21):8145-8
Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase.
Mao Y, Finnemann SC
Molecular biology of the cell 2012 Mar;23(6):1104-14
Molecular biology of the cell 2012 Mar;23(6):1104-14
Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin.
Yu CC, Nandrot EF, Dun Y, Finnemann SC
Free radical biology & medicine 2012 Feb 1;52(3):660-670
Free radical biology & medicine 2012 Feb 1;52(3):660-670
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Supportive validation
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- GeneTex (provider)
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- Experimental details
- Mouse tissue extract (50 ?g) was separated by 7.5% SDS-PAGE, and the membrane was blotted with RPE65 antibody [N1C3] (GTX103472) diluted at 1:1000.