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- Antigen structure
- References [240]
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- Product number
- 16475-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16475-1-AP, RRID:AB_2242567
- Product name
- Albumin antibody
- Antibody type
- Polyclonal
- Description
- Albumin antibody (Cat. #16475-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references PGK1 Lactylation-Driven Self-Reinforcing Loop Orchestrates Glycolytic Reprogramming in FSP1(+) Macrophages in Liver Fibrosis.
CircRNA-encoded RIPK1-98 protein drives lung adenocarcinoma progression.
Microfluidic fabricated cell-laden microgels aggregated into artificial liver microtissue to ameliorate drug-induced liver injury.
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
Hepatocyte TIA1 constrains metabolic steatohepatitis by translationally suppressing Srebf1 mRNA in stress granules.
Systemic Oxidative Stress and Oxidized Albumin Mediate the Pathogenic Kidney-to-Gut Crosstalk by Disrupting Intestinal Barrier Integrity.
Synergistic disruption of the blood-brain barrier in tree shrews by Methamphetamine and HIV-1 Tat via TRPM2-Mediated astrocyte inflammation.
The impact of mesenchymal stromal cells on the proliferation and functional maturation of liver organoids.
Targeting RNA Polymerase I Inhibits Ribosome Biogenesis to Block Liver Fibrosis Progression.
CDX2 Promotes Hepatic Specification of hiPSC-derived Endoderm Through the PI3K-Akt-GSK3β Pathway for Improved Therapeutic Efficacy.
Application of HepG2-derived organoid and organ-on-a-chip platforms in elucidating selenium-mediated protection against cadmium-induced liver dysfunction.
Black Sesame Pigment Ameliorates Non-Alcoholic Fatty Liver Disease via Modulation of the Gut-Liver Axis and HIF-1 Signaling Pathway.
Altered hepatic metabolism in Down syndrome.
In vivo self-assembled siRNAs targeting VEGFR2 and mTOR for renal cell carcinoma treatment.
Differential genetic analysis of ectrodactyly in a Fanconi anemia pedigree with FANCA mutations.
Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome.
MG53 mediates skeletal muscle-liver cross-talk and enhances alcohol metabolism in alcoholic liver disease.
Glimepiride alleviates blood-brain barrier disruption and neuroinflammation in mice with intracerebral haemorrhage.
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment.
Dexrazoxane Attenuates Blood-Brain Barrier Injury During Venoarterial Extracorporeal Membrane Oxygenation.
5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer.
Spermidine Exerts Neuroprotective Effects Following Intracerebral Hemorrhage in Mice Through Anti-Inflammation and Blood-Brain Barrier Protection.
Ischemia Reperfusion Injury Induced Systemic Inflammatory Response Following Interspecies Liver Transplantation.
A simplified method for immunostaining single endometrial and liver organoids.
Exosomes from small intestinal epithelium mediate cardiac fibrosis during aging.
Biomarkers for early detection and monitoring of abnormal brain development in mild fetal growth restriction.
Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells.
VEGFA induces anxiety and depression-like behaviors in post-stroke mice by regulating the permeability of the blood-brain barrier.
TRPC6 suppresses liver fibrosis by inhibiting hepatic stellate cell activation via CaMK4-CREB pathway.
Rational design of freeze-crosslinked polysaccharide sponges for efficient non-compressible hemostasis and liver repair.
Protein glycosylation modification as a novel forensic biomarker for discriminating monozygotic twins.
Dysregulated oxidative stress and lactate levels in treatment-resistant schizophrenia.
Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD(+) biosynthesis and thermogenesis in mice.
Numb-exon3 and full length Numb equivalently alleviate cholestatic liver fibrosis by inhibiting ductular reaction.
Enterococcus-derived cytolysin exacerbates ischemic stroke by disrupting the blood-brain barrier via NLRP3 activation.
Peroxynitrite regulates ER stress-mediated Ca(2+) flux to mitochondria characterizing cardiac microvascular ischemia-reperfusion injury associated with hyperhomocysteinemia.
Impaired ApoB secretion triggers enhanced secretion of ApoE to maintain triglyceride homeostasis in hepatoma cells.
Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion.
The Potential Hepatocyte Differentiation Targets and MSC Proliferation by FH1.
FGF2 Mediated USP42-PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration.
Quercetin down-regulates MCP-1 expression in autoimmune myocarditis via ERK1/2-C/EBPβ pathway: An integrative approach using network pharmacology and experimental models.
Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism.
Altered Hepatic Metabolism in Down Syndrome.
GP73-dependent regulation of exosome biogenesis promotes colorectal cancer liver metastasis.
Paeoniflorin alleviated STZ-induced diabetic retinopathy via regulation of the PDI/ADAM17/MerTK pathway.
ALB inhibits tumor cell proliferation and invasion by regulating immune microenvironment and endoplasmic reticulum stress in clear cell renal cell carcinoma.
Inducible global knockout of surfeit locus protein 4 in adult mice results in hypolipidemia, intestinal lipid accumulation, liver injury, and increased mortality.
Exosome-Mediated Lectin Pathway and Resistin-MIF-AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia.
An anti-CD19-exosome delivery system navigates the blood-brain barrier for targeting of central nervous system lymphoma.
Houshiheisan modulates the NF-κB/MLCK signaling pathway to protect the endothelial barrier in cerebral small vessel disease.
Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction.
Proteomic Profiling and Therapeutic Targeting of Oxidative Stress in Autoimmune Encephalitis.
Sterically chained amino acid-rich water-soluble carbon quantum dots as a robust tumor-targeted drug delivery platform.
TRPML1 ion channel promotes HepaRG cell differentiation under simulated microgravity conditions.
20(S)-Ginsenoside Rg3 Partially Induces Maturation of HepG2 Cells via the AMPK/HNF4A Pathway.
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Liver-Skin Microphysiological System for Evaluating Topical Drug Delivery-Induced Liver Injury.
Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia.
Δ(9)-tetrahydrocannabinol induces blood-brain barrier disruption: Involving the activation of CB1R and oxidative stress.
Hepatic stellate cell-specific Kcnma1 deletion mitigates metabolic dysfunction-associated steatotic liver disease progression via upregulating Amphiregulin secretion.
Small and Large Extracellular Vesicles From Human Preovulatory Follicular Fluid Display Distinct ncRNA Cargo Profiles and Differential Effects on KGN Granulosa Cells.
GPR146 regulates CYP7A1 transcription in cells and in vivo of mice.
Identifying the target, mechanism, and agonist of α-ketoglutaric acid in delaying mesenchymal stem cell senescence.
Urinalysis of a Hantaan virus-infected mouse model of hemorrhagic fever with renal syndrome.
Platycodin D-mediated METTL16 downregulation promotes docetaxel treatment of prostate cancer by regulating ferroptosis.
Inflammatory pain resolution by mouse serum-derived small extracellular vesicles.
Therapeutic potential of simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation.
snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification.
Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer's model.
The interactive toxic effect of homocysteine and copper on cardiac microvascular endothelial cells during ischemia-reperfusion injury.
Engineered neutrophil membrane-camouflaged nanocomplexes for targeted siRNA delivery against myocardial ischemia reperfusion injury.
Sulfonated albumin from hepatocytes accelerates liver fibrosis in nonalcoholic fatty liver disease through endoplasmic reticulum stress.
Microperfused Biomimetic Liver-on-a-Chip for High-Throughput Hepatotoxicity Screening.
Targeting Macrophage Migration Inhibitory Factor Ameliorates Brain Injury After Intracerebral Hemorrhage in Male Mice.
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Sodium thiosulfate does not affect energy metabolism or organ (dys)function during resuscitation from murine trauma-and-hemorrhage.
PHLDA2 promotes breast cancer metastasis by co-opting a developmental program for placental vascular remodeling.
Morphine-induced hyperalgesia impacts small extracellular vesicle microRNA composition and function.
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier.
Remote limb ischemic conditioning alleviates steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk.
In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma.
C176-loaded and phosphatidylserine-modified nanoparticles treat retinal neovascularization by promoting M2 macrophage polarization.
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD.
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis.
Morphine-induced hyperalgesia impacts small extracellular vesicle miRNA composition and function.
Functional cardiac consequences of β-adrenergic stress-induced injury in a model of Duchenne muscular dystrophy.
Serum apolipoprotein H determines ferroptosis resistance by modulating cellular lipid composition.
Arginine deprivation/citrulline augmentation with ADI-PEG20 as novel therapy for complications in type 2 diabetes.
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice.
AGR2-mediated unconventional secretion of 14-3-3ε and α-actinin-4, responsive to ER stress and autophagy, drives chemotaxis in canine mammary tumor cells.
Lipotoxic hepatocyte derived LIMA1 enriched small extracellular vesicles promote hepatic stellate cells activation via inhibiting mitophagy.
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
Blood-based CNS regionally and neuronally enriched extracellular vesicles carrying pTau217 for Alzheimer's disease diagnosis and differential diagnosis.
Millimeter-scale magnetic implants paired with a fully integrated wearable device for wireless biophysical and biochemical sensing.
Generation of Highly Functional Hepatocyte-like Organoids from Human Adipose-Derived Mesenchymal Stem Cells Cultured with Endothelial Cells.
Apolipoprotein O modulates cholesterol metabolism via NRF2/CYB5R3 independent of LDL receptor.
Superporous sponge prepared by secondary network compaction with enhanced permeability and mechanical properties for non-compressible hemostasis in pigs.
Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis.
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
Investigation of ferroptosis-associated molecular subtypes and immunological characteristics in lupus nephritis based on artificial neural network learning.
A PNPLA3-Deficient iPSC-Derived Hepatocyte Screen Identifies Pathways to Potentially Reduce Steatosis in Metabolic Dysfunction-Associated Fatty Liver Disease.
Apomorphine Suppresses the Progression of Steatohepatitis by Inhibiting Ferroptosis.
Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury.
A novel lung cancer stem cell extracellular vesicles lncRNA ROLLCSC modulate non-stemness cancer cell plasticity through miR-5623-3p and miR-217-5p targeting lipid metabolism.
IFITM3 overexpression reverses insufficient healing benefits of small extracellular vesicles from high-fat-diet BMSCs in sepsis via the HMGB1 pathway.
Manipulating HGF signaling reshapes the cirrhotic liver niche and fills a therapeutic gap in regeneration mediated by transplanted stem cells.
Single-cell transcriptome analysis of aging mouse liver.
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
Inflammatory pain resolution by mouse serum-derived small extracellular vesicles.
S-Nitrosylation of NOTCH1 Regulates Mesenchymal Stem Cells Differentiation Into Hepatocyte-Like Cells by Inhibiting Notch Signalling Pathway.
Integrated metabolomics and network pharmacology analysis to reveal the protective effect of Complanatoside A on nonalcoholic fatty liver disease.
Mice Hepatic Organoids for Modeling Nonalcoholic Fatty Liver Disease and Drug Response.
C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport.
Intimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis.
Western Blot Protocols for Analysis of CCN Proteins and Fragments in Exosomes, Vesicle-Free Fractions, and Cells.
Low-dose lipopolysaccharide inducing continuous and obvious increase in urinary protein in hyperglycemic rats and the underlying mechanism.
Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.
Mechanism of Wuzhuyu decoction on alcohol-induced gastric ulcers using integrated network analysis and metabolomics.
Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse.
Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injury.
miR-32-5p induces hepatic steatosis and hyperlipidemia by triggering de novo lipogenesis.
MDIG-mediated H3K9me3 demethylation upregulates Myc by activating OTX2 and facilitates liver regeneration.
Inhibition of free heme-catalyzed Fenton-like reaction prevents non-alcoholic fatty liver disease by hepatocyte-targeted hydrogen delivery.
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes.
Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner.
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
Urinary SPP1 has potential as a non-invasive diagnostic marker for focal segmental glomerulosclerosis.
Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice.
Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.
PTEN/AKT and Wnt/β-catenin signaling pathways regulate the proliferation of Lgr5+ cells in liver cancer.
Chemical modification of AAV9 capsid with N-ethyl maleimide alters vector tissue tropism.
Salvianolic acid A attenuates inflammation-mediated atherosclerosis by suppressing GRP78 secretion of endothelial cells.
Herpetin Promotes Bone Marrow Mesenchymal Stem Cells to Alleviate Carbon Tetrachloride-Induced Acute Liver Injury in Mice.
BM-MSCs overexpressing the Numb enhance the therapeutic effect on cholestatic liver fibrosis by inhibiting the ductular reaction.
HPF Modulates the Differentiation of BMSCs into HLCs and Promotes the Recovery of Acute Liver Injury in Mice.
Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy.
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Tissue-Engineered Hepatocyte Sheets Supplemented with Adipose-Derived Stem Cells.
A Scd1-mediated metabolic alteration participates in liver responses to low-dose bavachin.
Small extracellular vesicles derived from human adipose-derived mesenchymal stromal cells cultured in a new chemically-defined contaminate-free media exhibit enhanced biological and therapeutic effects on human chondrocytes in vitro and in a mouse osteoarthritis model.
Caveolin-1 ameliorates acetaminophen-aggravated inflammatory damage and lipid deposition in non-alcoholic fatty liver disease via the ROS/TXNIP/NLRP3 pathway.
Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways.
Integrated omics landscape of hepatocellular carcinoma suggests proteomic subtypes for precision therapy.
Modeling Colorectal Cancer-Induced Liver Portal Vein Microthrombus on a Hepatic Lobule Chip.
Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.
Fenofibrate enhances lipid deposition via modulating PPARγ, SREBP-1c, and gut microbiota in ob/ob mice fed a high-fat diet.
ATP5O Hypo-crotonylation Caused by HDAC2 Hyper-Phosphorylation Is a Primary Detrimental Factor for Downregulated Phospholipid Metabolism under Chronic Stress.
GLP-1 RA Improves Diabetic Retinopathy by Protecting the Blood-Retinal Barrier through GLP-1R-ROCK-p-MLC Signaling Pathway.
Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.
Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy.
Pore-forming protein βγ-CAT promptly responses to fasting with capacity to deliver macromolecular nutrients.
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
A novel anti-TNF-α drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis.
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
Blood plasma derived extracellular vesicles (BEVs): particle purification liquid chromatography (PPLC) and proteomic analysis reveals BEVs as a potential minimally invasive tool for predicting response to breast cancer treatment.
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Microglia secrete miR-146a-5p-containing exosomes to regulate neurogenesis in depression.
Constructing vascularized hepatic tissue by cell-assembled viscous tissue sedimentation method and its application for vascular toxicity assessment.
Prenatal glucocorticoid administration accelerates the maturation of fetal rat hepatocytes.
Deletion of p38γ attenuates ethanol consumption- and acetaminophen-induced liver injury in mice through promoting Dlg1.
Letter to the Editor: False Hypercortisolemia Due to Abnormal Albumin-Cortisol Binding in a Patient with Familial Dysalbuminemic Hyperthyroxinemia.
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles.
Expression and activation of the ketone body receptor HCAR2/GPR109A promotes preservation of retinal endothelial cell barrier function.
A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma.
Universal Markers for hiPSCs Residue Detection.
Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes.
Profiling Blood Serum Extracellular Vesicles in Plaque Psoriasis and Psoriatic Arthritis Patients Reveals Potential Disease Biomarkers.
Establishment of Functional Liver Spheroids From Human Hepatocyte-Derived Liver Progenitor-Like Cells for Cell Therapy.
The Cordyceps militaris-Derived Polysaccharide CM1 Alleviates Atherosclerosis in LDLR((-/-)) Mice by Improving Hyperlipidemia.
PTEN-mediated AKT/β-catenin signaling enhances the proliferation and expansion of Lgr5+ hepatocytes.
An Albumin-Binding Domain Peptide Confers Enhanced Immunoprotection Against Viral Myocarditis by CVB3 VP1 Vaccine.
The combined induction of liver progenitor cells and the suppression of stellate cells by small molecules reverts chronic hepatic dysfunction.
Circulating microRNAs from the mouse tibia fracture model reflect the signature from patients with complex regional pain syndrome.
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Changes in the hepatic differentiation potential of human mesenchymal stem cells aged in vitro.
Hypoxia Preconditioning Promotes the Proliferation and Migration of Human Urine-Derived Stem Cells in Chronically Injured Liver of Mice by Upregulating CXCR4.
In vivo self-assembled small RNAs as a new generation of RNAi therapeutics.
The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation.
Assessment of long-term functional maintenance of primary human hepatocytes to predict drug-induced hepatoxicity in vitro.
Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation.
Exosomes derived from astrocytes after oxygen-glucose deprivation promote differentiation and migration of oligodendrocyte precursor cells in vitro.
Enterically derived high-density lipoprotein restrains liver injury through the portal vein.
On-Chip Construction of Liver Lobules with Self-Assembled Perfusable Hepatic Sinusoid Networks.
Proximity Proteomics Has Potential for Extracellular Vesicle Identification.
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells.
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
A Novel Mouse Model for Cerebral Venous Sinus Thrombosis.
Impaired Glucocorticoid Receptor Signaling Aggravates Lung Injury after Hemorrhagic Shock.
Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/-)) hamsters.
Hippocampal microglia CD40 mediates NPSLE cognitive dysfunction in mice.
All-trans-retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating autophagy.
Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development.
CRISPR-Cas9-Mediated In Vivo Gene Integration at the Albumin Locus Recovers Hemostasis in Neonatal and Adult Hemophilia B Mice.
Isoform 1 of Fibrinogen Alpha Chain Precursor is a Potential Biomarker for Steroid-Induced Osteonecrosis of the Femoral Head.
Microglial activation and responses to vasculature that result from an acute LPS exposure.
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
Myofibroblast induces hepatocyte-to-ductal metaplasia via laminin-ɑvβ6 integrin in liver fibrosis.
Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion.
An extracorporeal bioartificial liver embedded with 3D-layered human liver progenitor-like cells relieves acute liver failure in pigs.
Rab27a dependent exosome releasing participated in albumin handling as a coordinated approach to lysosome in kidney disease.
Construction of a High-Expression System in Bacillus through Transcriptomic Profiling and Promoter Engineering.
Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells.
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.
Comprehensive study of dexamethasone on albumin biogenesis during normal and pathological renal conditions.
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Cellular, Extracellular and Extracellular Vesicular miRNA Profiles of Pre-Ovulatory Follicles Indicate Signaling Disturbances in Polycystic Ovaries.
The Effect of Matrix Stiffness on Human Hepatocyte Migration and Function-An In Vitro Research.
Long-term Production of Glycogen and Hepatic-Derived, Cell-Invasion-Promoting Chemokines by Ultrasound-Driven Hepatic-Differentiated Human Bone Marrow Mesenchymal Stem Cells.
Imbalance in mitochondrial dynamics induced by low PGC-1α expression contributes to hepatocyte EMT and liver fibrosis.
Locus Coeruleus Degeneration Induces Forebrain Vascular Pathology in a Transgenic Rat Model of Alzheimer's Disease.
Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction.
A critical role of VMP1 in lipoprotein secretion.
ATRA induces the differentiation of hepatic progenitor cells by upregulating microRNA-200a.
Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance.
Blocking CXCR3 with AMG487 ameliorates the blood-retinal barrier disruption in diabetic mice through anti-oxidative.
Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells.
Peptidome profiles in melamine diet-induced bladder stones in C57BL/6 mice.
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Ultrasound Irradiation Combined with Hepatocyte Growth Factor Accelerate the Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Yi Guan Jian decoction may enhance hepatic differentiation of bone marrow‑derived mesenchymal stem cells via SDF‑1 in vitro.
Thyroid Hormone Metabolism Defects in a Mouse Model of SBP2 Deficiency.
Ex Vivo Stromal Cell-Derived Factor 1-Mediated Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells into Hepatocytes Is Enhanced by Chinese Medicine Yiguanjian Drug-Containing Serum.
miR-706 inhibits the oxidative stress-induced activation of PKCα/TAOK1 in liver fibrogenesis.
A long non-coding RNA, APOA4-AS, regulates APOA4 expression depending on HuR in mice.
A virus-like particle-based connective tissue growth factor vaccine suppresses carbon tetrachloride-induced hepatic fibrosis in mice.
The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress.
Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.
Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model.
Revival, characterization, and hepatitis B virus infection of cryopreserved human fetal hepatocytes.
Long-term maintenance of human fetal hepatocytes and prolonged susceptibility to HBV infection by co-culture with non-parenchymal cells.
Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver.
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis.
Tang M, Sun M, Zhang H, Chen J, Wang Y, Jiang Y, Qin L, Wang H, Zhu F, Yang C
Research (Washington, D.C.) 2026;9:1177
Research (Washington, D.C.) 2026;9:1177
CircRNA-encoded RIPK1-98 protein drives lung adenocarcinoma progression.
Sun Q, Chi R, Zhang X, Chen T, Xu X, Ma L, Tian X, Miao Y, Yu Y, Kang R, Kroemer G, Shi Y, Tang D, Wang J
Developmental cell 2026 May 13;61(5):1092-1110.e12
Developmental cell 2026 May 13;61(5):1092-1110.e12
Microfluidic fabricated cell-laden microgels aggregated into artificial liver microtissue to ameliorate drug-induced liver injury.
Li F, Xue T, Xu Y, Wang H, Ju E, Li M, Tao Y
Biomaterials 2026 Mar;326:123710
Biomaterials 2026 Mar;326:123710
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
Wu J, Cui G, Lin Z, Lin W, Zhang Y, Zhou T, He P, Zhang Y, Yao G
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Hepatocyte TIA1 constrains metabolic steatohepatitis by translationally suppressing Srebf1 mRNA in stress granules.
Liu R, Chen J, Wang J, Zhang T, Xia Y, Feng J, Guo C, Xue L, Zhou Y
Cell death & disease 2026 Mar 24;17(1)
Cell death & disease 2026 Mar 24;17(1)
Systemic Oxidative Stress and Oxidized Albumin Mediate the Pathogenic Kidney-to-Gut Crosstalk by Disrupting Intestinal Barrier Integrity.
Cheng J, Sui Y, Wang X, Xu Y, Jiang R, Zhang Y, Shi Z, Suda M, Fan J, Yao J
Biomolecules 2026 Mar 18;16(3)
Biomolecules 2026 Mar 18;16(3)
Synergistic disruption of the blood-brain barrier in tree shrews by Methamphetamine and HIV-1 Tat via TRPM2-Mediated astrocyte inflammation.
Teng HX, Huang J, Miao L, Yang X, Xu LS, Zhao YJ, Li J, Zeng XF
Brain, behavior, and immunity 2026 Mar 14;136:106538
Brain, behavior, and immunity 2026 Mar 14;136:106538
The impact of mesenchymal stromal cells on the proliferation and functional maturation of liver organoids.
Luo S, Mao C, Wu F, Huang X, Wu W, Huang T, Liu D
Biology direct 2026 Mar 10;21(1)
Biology direct 2026 Mar 10;21(1)
Targeting RNA Polymerase I Inhibits Ribosome Biogenesis to Block Liver Fibrosis Progression.
Luo W, Yi L, Zhang Y, Zhou J, Li S, Abouelnazar FA, Wang Y, Yan Y
Liver international : official journal of the International Association for the Study of the Liver 2026 Jan;46(1):e70478
Liver international : official journal of the International Association for the Study of the Liver 2026 Jan;46(1):e70478
CDX2 Promotes Hepatic Specification of hiPSC-derived Endoderm Through the PI3K-Akt-GSK3β Pathway for Improved Therapeutic Efficacy.
Bai F, Duan J, Yang D, Lai X, Ji H, Zhu X, He X, Hu A
Stem cell reviews and reports 2026 Jan;22(1):503-522
Stem cell reviews and reports 2026 Jan;22(1):503-522
Application of HepG2-derived organoid and organ-on-a-chip platforms in elucidating selenium-mediated protection against cadmium-induced liver dysfunction.
Ren M, Feng Q, Lu S, Xiao W, Deng Q, Yang X, Yan C, Ren Z, Yan B, Wu Y, Huang S, Yang X, Ma P, Su L
NPJ science of food 2026 Jan 6;10(1):22
NPJ science of food 2026 Jan 6;10(1):22
Black Sesame Pigment Ameliorates Non-Alcoholic Fatty Liver Disease via Modulation of the Gut-Liver Axis and HIF-1 Signaling Pathway.
Huang Q, Liang Z, Li Q, Wang K, Zhu S, Xiao W, Zhou L
Antioxidants (Basel, Switzerland) 2026 Jan 30;15(2)
Antioxidants (Basel, Switzerland) 2026 Jan 30;15(2)
Altered hepatic metabolism in Down syndrome.
Dunn LN, Niemeyer BF, Eduthan NP, Schade KA, Waugh KA, Brown C, Rachubinski AL, Timkovich AE, Orlicky DJ, Galbraith MD, Espinosa JM, Sullivan KD
Cell reports 2026 Jan 27;45(1):116835
Cell reports 2026 Jan 27;45(1):116835
In vivo self-assembled siRNAs targeting VEGFR2 and mTOR for renal cell carcinoma treatment.
Fu J, Zhou X, Mi J, Zhou L, Ma L, Guo J, Lei J, Qu S, Fu Z, Liu T, Chen X, Yang R
Asian journal of pharmaceutical sciences 2026 Feb;21(1):101126
Asian journal of pharmaceutical sciences 2026 Feb;21(1):101126
Differential genetic analysis of ectrodactyly in a Fanconi anemia pedigree with FANCA mutations.
Zhang JH, Xu ZY, Yu HP, Wang RL, Zhu J, Geng ZB, Chen L, Ruan DD, Huang FM, Gao MZ, Li YF, Zhang XK, Zhang L, Fang ZT, Liao LS, Zheng XL, Hu B, Luo JW
MedScience 2026 Feb;20(1):173-185
MedScience 2026 Feb;20(1):173-185
Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome.
Duan R, Wang X, Wang Q, Zhou X, Gao S, Sun Y, Feng Q, Li Z, Yang Z, Ding J, Chen Z, Duan J, Yang Y
Cell reports 2026 Feb 24;45(2):116942
Cell reports 2026 Feb 24;45(2):116942
MG53 mediates skeletal muscle-liver cross-talk and enhances alcohol metabolism in alcoholic liver disease.
Shu T, Zeng X, Wang J, Jiang H, Wang Y, Zhang M, Jiang L, He B, Yang L, Liu N, Tang M, Jiang Y, Zhang L, Chen P, Xie J, Fang D, Lee KE, Chen Y, Kim J, Liu R, Ye Y, Han Y, Ma J, Zeng C
Nature communications 2026 Feb 13;17(1)
Nature communications 2026 Feb 13;17(1)
Glimepiride alleviates blood-brain barrier disruption and neuroinflammation in mice with intracerebral haemorrhage.
Zhou H, Wang Q, Liu Y, Zhang X, Chen Y, Guo P, Yong VW, Xue M
Annals of medicine 2026 Dec;58(1):2663133
Annals of medicine 2026 Dec;58(1):2663133
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.
Mathiowetz AJ, Meymand ES, Parlakgül G, van Hilten N, Torres EF, Artico LL, Deol KK, Lange M, Pang SP, Doubravsky CE, Roberts MA, Jorgens DM, Zalpuri R, Kang M, Boone C, Parks BW, Zhang Y, Morgens DW, Newman ET, Zhou Y, Talukdar S, Grabe M, Ku G, Levine TP, Arruda AP, Olzmann JA
Nature 2026 Apr;652(8109):462-470
Nature 2026 Apr;652(8109):462-470
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment.
Sun S, Hu H, Chen L, Gao Y, Sun P, Chen L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 3;:e21098
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 3;:e21098
Dexrazoxane Attenuates Blood-Brain Barrier Injury During Venoarterial Extracorporeal Membrane Oxygenation.
Shen X, Li J, Ma X, Li H, Shao K, Wei S, Zhang X, Li M, Wu X, Li Y, Ge Z
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2026 Apr 1;72(4):302-308
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2026 Apr 1;72(4):302-308
5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer.
Chen H, Gao T, Chen H, Zhang L, Chen X, Duolikun M, Li X, Li X, Chen L, Gao H, Li Q, Hao X, Zhou P, Ren N, Lin J, Wang Y
Extracellular vesicles and circulating nucleic acids 2025;6(4):822-842
Extracellular vesicles and circulating nucleic acids 2025;6(4):822-842
Spermidine Exerts Neuroprotective Effects Following Intracerebral Hemorrhage in Mice Through Anti-Inflammation and Blood-Brain Barrier Protection.
Qi L, Zhang X, Liu Y, Guo P, Siddique R, Mazhar M, Xue S, Yong VW, Xue M
Journal of inflammation research 2025;18:7401-7417
Journal of inflammation research 2025;18:7401-7417
Ischemia Reperfusion Injury Induced Systemic Inflammatory Response Following Interspecies Liver Transplantation.
Rao JS, Rangarajan P, Shetty A, Steinhoff M, Tran A, Crane AT, Low WC, Steer CJ, Ramachandran S
Hepatic medicine : evidence and research 2025;17:161-176
Hepatic medicine : evidence and research 2025;17:161-176
A simplified method for immunostaining single endometrial and liver organoids.
Saadeldin IM, Alshehri E, AlThubyani M, Almohanna F, Matic G, Ahmed HA, Mir TA, Assiri AM
Journal, genetic engineering & biotechnology 2025 Sep;23(3):100550
Journal, genetic engineering & biotechnology 2025 Sep;23(3):100550
Exosomes from small intestinal epithelium mediate cardiac fibrosis during aging.
He Y, Lu X, Pang S, Xia F, Lv Y, Yu J, Ding G, Sheng Y
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 Sep 19;80(10)
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 Sep 19;80(10)
Biomarkers for early detection and monitoring of abnormal brain development in mild fetal growth restriction.
Onoda A, Kitase Y, Coq JO, Ueda K, Shimizu S, Tsuji M, Hayakawa M, Sato Y
iScience 2025 Sep 19;28(9):113237
iScience 2025 Sep 19;28(9):113237
Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells.
Guo Y, Yu XR, Gu HD, Wang YJ, Yang ZG, Chi JF, Zhang LP, Lin H
World journal of diabetes 2025 Sep 15;16(9):109553
World journal of diabetes 2025 Sep 15;16(9):109553
VEGFA induces anxiety and depression-like behaviors in post-stroke mice by regulating the permeability of the blood-brain barrier.
Gou Y, Zhang J, Liu H, Zhu C, Song X, Geng S, Peng Q, Jin S, Wang X, Xiao Y, Zhang F, Zhang Z, Song J
Neuroscience 2025 Sep 13;583:63-75
Neuroscience 2025 Sep 13;583:63-75
TRPC6 suppresses liver fibrosis by inhibiting hepatic stellate cell activation via CaMK4-CREB pathway.
Jiang S, Wang Y, Ren Y, Tang Q, Xue C, Wang Z, Zhang Q, Hu Y, Wang H, Zhao F, Zhu MX, Cao Z
British journal of pharmacology 2025 Oct;182(20):5004-5022
British journal of pharmacology 2025 Oct;182(20):5004-5022
Rational design of freeze-crosslinked polysaccharide sponges for efficient non-compressible hemostasis and liver repair.
Zhou P, Ding W, Wang H, Li X, Cui J, Liu G, Chen Z, Tang C, Jiang Y, Zhang L, Sun D
Carbohydrate polymers 2025 Oct 15;366:123889
Carbohydrate polymers 2025 Oct 15;366:123889
Protein glycosylation modification as a novel forensic biomarker for discriminating monozygotic twins.
Chen YZ, Li Y, Wang YL, Rakha A, Liu Z, Wang DY, Wang SW, Sun ML, Wang H, Adnan A, Yao J
Forensic science international 2025 Nov;376:112596
Forensic science international 2025 Nov;376:112596
Dysregulated oxidative stress and lactate levels in treatment-resistant schizophrenia.
Fang Y, Zhang T, Xu K, Wang L, He J, Liao Y, Yuan N, Tang J
Brain, behavior, and immunity 2025 Nov;130:106111
Brain, behavior, and immunity 2025 Nov;130:106111
Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD(+) biosynthesis and thermogenesis in mice.
Yoshioka K, Sugimoto T, Oyabu M, Ito N, Kodama A, Kamei Y, Imai SI
npj aging 2025 Nov 24;11(1):106
npj aging 2025 Nov 24;11(1):106
Numb-exon3 and full length Numb equivalently alleviate cholestatic liver fibrosis by inhibiting ductular reaction.
Xu YN, Zong MY, Xu W, Zhang SH, Wang DY, Zheng XR, Xing FF, Zhan JY, Chen JM, Chen GF, Liu P, Liu W, Mu YP
Scientific reports 2025 Nov 14;15(1):39983
Scientific reports 2025 Nov 14;15(1):39983
Enterococcus-derived cytolysin exacerbates ischemic stroke by disrupting the blood-brain barrier via NLRP3 activation.
Huang JN, Zhuang WH, Lin YS, Xu JX, Zhang YL, Li J, Huang M, Xie CL, Xu RT
Journal of neuroinflammation 2025 Nov 11;22(1):266
Journal of neuroinflammation 2025 Nov 11;22(1):266
Peroxynitrite regulates ER stress-mediated Ca(2+) flux to mitochondria characterizing cardiac microvascular ischemia-reperfusion injury associated with hyperhomocysteinemia.
Liu H, Yu S, Gao S, Liu X, Qiu C, Wang N, Tan X, Zhao K, He Q, Zhang W
Journal of translational medicine 2025 Nov 10;23(1):1254
Journal of translational medicine 2025 Nov 10;23(1):1254
Impaired ApoB secretion triggers enhanced secretion of ApoE to maintain triglyceride homeostasis in hepatoma cells.
Shinozaki K, Honda T, Yamaji K, Nishijima E, Ichi I, Yamane D
Journal of lipid research 2025 May;66(5):100795
Journal of lipid research 2025 May;66(5):100795
Lipocalin 2 Facilitates the Initial Compromise of the Blood-Brain Barrier Integrity in Chronic Cerebral Hypoperfusion.
Nie Q, Zhang L, Gu Z, Li Y, Bi X
CNS neuroscience & therapeutics 2025 May;31(5):e70438
CNS neuroscience & therapeutics 2025 May;31(5):e70438
The Potential Hepatocyte Differentiation Targets and MSC Proliferation by FH1.
Luo S, Wu F, Jin Y, Liu D
Journal of cellular and molecular medicine 2025 May;29(9):e70601
Journal of cellular and molecular medicine 2025 May;29(9):e70601
FGF2 Mediated USP42-PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration.
Yang N, Tian Q, Lei Z, Wang S, Cheng N, Wang Z, Jiang X, Zheng X, Xu W, Ye M, Zhao L, Wen M, Niu J, Sun W, Shen P, Huang Z, Li X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2408724
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2408724
Quercetin down-regulates MCP-1 expression in autoimmune myocarditis via ERK1/2-C/EBPβ pathway: An integrative approach using network pharmacology and experimental models.
Liu J, Li Z, Liu W, Jiang Z, Zhang X, Yuan Y, Shen Y
International immunopharmacology 2025 May 8;154:114559
International immunopharmacology 2025 May 8;154:114559
Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism.
Jiang J, Gao Y, Wang J, Huang Y, Yang R, Zhang Y, Ma Y, Wen Y, Luo G, Zhang S, Cao Y, Yu M, Wang Q, Hu S, Wang K, Guo X, Gonzalez FJ, Liu Y, Liu H, Xie Q, Xie C
Cell metabolism 2025 May 6;37(5):1119-1136.e13
Cell metabolism 2025 May 6;37(5):1119-1136.e13
Altered Hepatic Metabolism in Down Syndrome.
Dunn LN, Niemeyer BF, Eduthan NP, Schade KA, Waugh KA, Brown C, Rachubinski AL, Timkovich AE, Orlicky DJ, Galbraith MD, Espinosa JM, Sullivan KD
bioRxiv : the preprint server for biology 2025 May 31;
bioRxiv : the preprint server for biology 2025 May 31;
GP73-dependent regulation of exosome biogenesis promotes colorectal cancer liver metastasis.
Huang L, Wei M, Li H, Yu M, Wan L, Zhao R, Gao Q, Sun L, Hou X, Mo Y, Huang Q, Zhen L, Yang X, Li J, Wang N, Zhang C, Jin H, Zhou L, Xu Y, Lin H, Zhang X, Li B, Han Y, Yuan J, Zhang R, Wu F, Zhong H, Wei C
Molecular cancer 2025 May 26;24(1):151
Molecular cancer 2025 May 26;24(1):151
Paeoniflorin alleviated STZ-induced diabetic retinopathy via regulation of the PDI/ADAM17/MerTK pathway.
Qi X, Guo H, Xia X, Liu Y, Qiu S, Lin T, He W, Jin L, Cheng J, Hao L, Liu W, Hu H
International immunopharmacology 2025 May 16;155:114571
International immunopharmacology 2025 May 16;155:114571
ALB inhibits tumor cell proliferation and invasion by regulating immune microenvironment and endoplasmic reticulum stress in clear cell renal cell carcinoma.
Zhu JM, Chen SH, Xu YC, Gao RC, Cai H, Zheng QS, Sun XL, Xue XY, Wei Y, Xu N
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167672
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167672
Inducible global knockout of surfeit locus protein 4 in adult mice results in hypolipidemia, intestinal lipid accumulation, liver injury, and increased mortality.
Chen W, Chen Y, Song B, Zhai L, Tao G, Wang B, Liu B, Wang H, Zhang CX, Gu HM, Yin D, Qin S, Zhang DW
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Mar;1870(2):159577
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Mar;1870(2):159577
Exosome-Mediated Lectin Pathway and Resistin-MIF-AA Metabolism Axis Drive Immune Dysfunction in Immune Thrombocytopenia.
Li J, Wang X, Chen Y, Sun X, Fu L, Xin Q, Zhang H, Qin B, Sun N, Li Y, Xu Y, Yang H, Huo D, Dong Y, Wang S, Zhao M, Lin Q, Wang F, Yue B, Gao Y, Jiang Y, Guo R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412378
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412378
An anti-CD19-exosome delivery system navigates the blood-brain barrier for targeting of central nervous system lymphoma.
Zhao M, Li Q, Chai Y, Rong R, He L, Zhang Y, Cui H, Xu H, Zhang X, Wang Z, Yuan S, Chen M, He C, Zhang H, Qin L, Hu R, Zhang X, Zhuang W, Li B
Journal of nanobiotechnology 2025 Mar 5;23(1):173
Journal of nanobiotechnology 2025 Mar 5;23(1):173
Houshiheisan modulates the NF-κB/MLCK signaling pathway to protect the endothelial barrier in cerebral small vessel disease.
Cheng HF, Yang QY, Xie YH, Zhang YW, Zhang QX
Journal of ethnopharmacology 2025 Mar 26;344:119502
Journal of ethnopharmacology 2025 Mar 26;344:119502
Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction.
Liao L, Liu Z, Liu L, Huang C, Li Y, Mao C, Xu R, Liu H, Liu C, Peng Y, Lei T, Liang H, Yu S, Qian J, Wu X, Wang B, Lin Y, Zhou J, Li Q, Li C, Wang K
Nature communications 2025 Mar 2;16(1):2112
Nature communications 2025 Mar 2;16(1):2112
Proteomic Profiling and Therapeutic Targeting of Oxidative Stress in Autoimmune Encephalitis.
Zhang F, Zhang C, Sun W, Xie S, Wu P, Zeng G, Liu X
Journal of molecular neuroscience : MN 2025 Mar 19;75(2):38
Journal of molecular neuroscience : MN 2025 Mar 19;75(2):38
Sterically chained amino acid-rich water-soluble carbon quantum dots as a robust tumor-targeted drug delivery platform.
Xie W, Wang H, Xu H, Su W, Yuan T, Chang J, Bai Y, Fan Y, Zhang Y, Li Y, Li X, Fan L
Nature communications 2025 Mar 19;16(1):2716
Nature communications 2025 Mar 19;16(1):2716
TRPML1 ion channel promotes HepaRG cell differentiation under simulated microgravity conditions.
Fan H, Lü D, Lu Z, Li H, Qi Z, Sun S, Guan D, Long M, Gao M, Liu S
NPJ microgravity 2025 Mar 15;11(1):9
NPJ microgravity 2025 Mar 15;11(1):9
20(S)-Ginsenoside Rg3 Partially Induces Maturation of HepG2 Cells via the AMPK/HNF4A Pathway.
Zheng L, Ding Y, Li X, Jia J, Li Y, Qi J
Iranian journal of public health 2025 Jun;54(6):1263-1271
Iranian journal of public health 2025 Jun;54(6):1263-1271
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Xia T, Yin H, Zhu Q, Zhang K, Xie H, Shan Y, Zhang S, Zhu R, Li K, Miao M, Lu Y, Wang Z, Zhao J, You Y, You B
Cell reports. Medicine 2025 Jun 17;6(6):102146
Cell reports. Medicine 2025 Jun 17;6(6):102146
Liver-Skin Microphysiological System for Evaluating Topical Drug Delivery-Induced Liver Injury.
Du K, Wang B, Yang N, Jin J, Liu W, Pu F, Zou L, Qu Z, Chen L
ACS omega 2025 Jun 17;10(23):24284-24295
ACS omega 2025 Jun 17;10(23):24284-24295
Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia.
Li Q, Dai H, Zhang S, Li P, Peng L, Chen Y, Guo Q, Yang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70664
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70664
Δ(9)-tetrahydrocannabinol induces blood-brain barrier disruption: Involving the activation of CB1R and oxidative stress.
Zhang Q, Huang W, Li T, Wang X, Lai X, Hu W, Li Z, Zeng X, Huang J, Zhang R
Neuropharmacology 2025 Jun 1;270:110366
Neuropharmacology 2025 Jun 1;270:110366
Hepatic stellate cell-specific Kcnma1 deletion mitigates metabolic dysfunction-associated steatotic liver disease progression via upregulating Amphiregulin secretion.
Zou Y, Wu J, Cheng S, Cheng D, Chen T, Guo X, Tang L, Su X, Zhang M, Zhang X, Liu Y, Zhang J, Bao Q, Hou S, Sun P, Li Y, Han B
Molecular metabolism 2025 Jul;97:102164
Molecular metabolism 2025 Jul;97:102164
Small and Large Extracellular Vesicles From Human Preovulatory Follicular Fluid Display Distinct ncRNA Cargo Profiles and Differential Effects on KGN Granulosa Cells.
Varik I, Saretok KJ, Rosenberg K, Quintero I, Puhka M, Volkova N, Trošin A, Guazzi P, Velthut-Meikas A
Journal of extracellular vesicles 2025 Jul;14(7):e70119
Journal of extracellular vesicles 2025 Jul;14(7):e70119
GPR146 regulates CYP7A1 transcription in cells and in vivo of mice.
Liu X, Han J, Li X, Zhang Z, Li J, Yao Y
Biochemical and biophysical research communications 2025 Jul 30;772:152045
Biochemical and biophysical research communications 2025 Jul 30;772:152045
Identifying the target, mechanism, and agonist of α-ketoglutaric acid in delaying mesenchymal stem cell senescence.
Cui Z, Li J, Li C, Deng S, Liu W, Lei T, Cao J, Wang Z, Wang X, Ma S, Zhu Y, Yang H, Chen P
Cell reports 2025 Jul 22;44(7):115917
Cell reports 2025 Jul 22;44(7):115917
Urinalysis of a Hantaan virus-infected mouse model of hemorrhagic fever with renal syndrome.
Sarii RS, Senarathne P, Yoshimatsu K
The Journal of veterinary medical science 2025 Jul 1;87(7):727-734
The Journal of veterinary medical science 2025 Jul 1;87(7):727-734
Platycodin D-mediated METTL16 downregulation promotes docetaxel treatment of prostate cancer by regulating ferroptosis.
Sun C, Sun X, Chen Y, Wu Y, Xiang C, Wu S
BMC cancer 2025 Jul 1;25(1):1042
BMC cancer 2025 Jul 1;25(1):1042
Inflammatory pain resolution by mouse serum-derived small extracellular vesicles.
Lin Z, Luo X, Wickman JR, Reddy D, DaCunza JT, Pande R, Tian Y, Kasimoglu EE, Triana V, Lee J, Furdui CM, Pink D, Sacan A, Ajit SK
Brain, behavior, and immunity 2025 Jan;123:422-441
Brain, behavior, and immunity 2025 Jan;123:422-441
Therapeutic potential of simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation.
Luo S, Wang X, Ma B, Liu D, Li L, Wang L, Ding N, Zou L, Wang J, Pan J, Sang D, Zhou H, Qu H, Lu Y, Yang L
Biomolecules & biomedicine 2025 Jan 30;25(3):632-647
Biomolecules & biomedicine 2025 Jan 30;25(3):632-647
snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification.
Liu B, Wu T, Miao BA, Ji F, Liu S, Wang P, Zhao Y, Zhong Y, Sundaram A, Zeng TB, Majcherska-Agrawal M, Keenan RJ, Pan T, He C
Cell 2025 Jan 23;188(2):465-483.e22
Cell 2025 Jan 23;188(2):465-483.e22
Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer's model.
Flynn CM, Omoluabi T, Janes AM, Rodgers EJ, Torraville SE, Negandhi BL, Nobel TE, Mayengbam S, Yuan Q
Alzheimer's research & therapy 2025 Jan 18;17(1):24
Alzheimer's research & therapy 2025 Jan 18;17(1):24
The interactive toxic effect of homocysteine and copper on cardiac microvascular endothelial cells during ischemia-reperfusion injury.
Liu X, Liu H, Wang N, Lai S, Qiu C, Gao S, Huang T, Zhang W
Chemico-biological interactions 2025 Feb 25;408:111387
Chemico-biological interactions 2025 Feb 25;408:111387
Engineered neutrophil membrane-camouflaged nanocomplexes for targeted siRNA delivery against myocardial ischemia reperfusion injury.
Jiang Y, Jiang R, Xia Z, Guo M, Fu Y, Wang X, Xie J
Journal of nanobiotechnology 2025 Feb 22;23(1):134
Journal of nanobiotechnology 2025 Feb 22;23(1):134
Sulfonated albumin from hepatocytes accelerates liver fibrosis in nonalcoholic fatty liver disease through endoplasmic reticulum stress.
Liu T, Sui M, Tian M, Wu N, Zhao S, Wang Y, Yang Y, Ma S, Jiao D, Wang L, Feng Y, Zhang Y, Qin C, Liu C, Qi J, Zhu Q
Free radical biology & medicine 2025 Feb 16;228:150-162
Free radical biology & medicine 2025 Feb 16;228:150-162
Microperfused Biomimetic Liver-on-a-Chip for High-Throughput Hepatotoxicity Screening.
Zhao J, Huang D, Wang J, Zhao Y
Small (Weinheim an der Bergstrasse, Germany) 2025 Dec;21(48):e05653
Small (Weinheim an der Bergstrasse, Germany) 2025 Dec;21(48):e05653
Targeting Macrophage Migration Inhibitory Factor Ameliorates Brain Injury After Intracerebral Hemorrhage in Male Mice.
Peng K, Liu H, Zhang W, Dai L, Fasoranti DO, Liu H, Li Q, Gu J, Liu F, Shi L, Li X, Liao W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71326
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71326
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Hao S, Luo J, Yuan S, Chen W, Zhang X, Zhao C, Xu H, Liu Z, Zhang D
Free radical biology & medicine 2025 Dec 1;240:1-14
Free radical biology & medicine 2025 Dec 1;240:1-14
Sodium thiosulfate does not affect energy metabolism or organ (dys)function during resuscitation from murine trauma-and-hemorrhage.
Feth M, Gracco M, Gröger M, Hogg M, Kress S, Hoffmann A, Calzia E, Wachter U, Radermacher P, Merz T
Intensive care medicine experimental 2025 Aug 6;13(1):80
Intensive care medicine experimental 2025 Aug 6;13(1):80
PHLDA2 promotes breast cancer metastasis by co-opting a developmental program for placental vascular remodeling.
Halas PV, Savage H, Hachey SJ, Lev T, Antony Samy ALP, Chan C, Jimenez S, Domadia RM, Lin I, Mallya S, Insua-Rodriguez J, Gonzalez J, Adam I, Alshetaiwi H, Hernandez GA, Longworth A, McMullen TP, Kessenbrock K, Hughes CCW, Ma D, Lawson DA
bioRxiv : the preprint server for biology 2025 Aug 23;
bioRxiv : the preprint server for biology 2025 Aug 23;
Morphine-induced hyperalgesia impacts small extracellular vesicle microRNA composition and function.
Reddy D, Lin Z, Ramanathan S, Luo X, Pande R, Tian Y, Side CM, Barker JM, Sacan A, Blendy JA, Ajit SK
The Journal of pharmacology and experimental therapeutics 2025 Apr;392(4):103398
The Journal of pharmacology and experimental therapeutics 2025 Apr;392(4):103398
The AKAP12-PKA axis regulates lipid homeostasis during alcohol-associated liver disease.
Thimme Gowda C, Siraganahalli Eshwaraiah M, Wang J, Lim Y, Tomasi ML, Mavila N, Ramani K
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
Signal transduction and targeted therapy 2025 Apr 9;10(1):109
Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier.
Chen Y, Zhou Y, Bai Y, Jia K, Zhang H, Chen Q, Song M, Dai Y, Shi J, Chen Z, Yan X, Shen Y
Neuron 2025 Apr 2;113(7):1082-1097.e8
Neuron 2025 Apr 2;113(7):1082-1097.e8
Remote limb ischemic conditioning alleviates steatohepatitis via extracellular vesicle-mediated muscle-liver crosstalk.
Zhao Y, Gao L, Chen J, Wei J, Lin G, Hu K, Zhao W, Wei W, Huang W, Gao L, Yuan A, Qian K, Chen AF, Pu J
Cell metabolism 2025 Apr 1;37(4):886-902.e7
Cell metabolism 2025 Apr 1;37(4):886-902.e7
In silico identification and verification of Tanshinone IIA-related prognostic genes in hepatocellular carcinoma.
Qian L, Xu Z, Luo T, Gao Z, Cheng K, He X, Zhang Z, Ren S, Zhu Y
Frontiers in immunology 2024;15:1482914
Frontiers in immunology 2024;15:1482914
C176-loaded and phosphatidylserine-modified nanoparticles treat retinal neovascularization by promoting M2 macrophage polarization.
Shao A, Jin L, Ge Y, Ye Z, Xu M, Zhou Y, Li Y, Wang L, Xu P, Jin K, Mao Z, Ye J
Bioactive materials 2024 Sep;39:392-405
Bioactive materials 2024 Sep;39:392-405
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD.
Song Z, Thepsuwan P, Hur WS, Torres M, Wu SA, Wei X, Tushi NJ, Wei J, Ferraresso F, Paton AW, Paton JC, Zheng Z, Zhang K, Fang D, Kastrup CJ, Jaiman S, Flick MJ, Sun S
Nature communications 2024 Oct 26;15(1):9244
Nature communications 2024 Oct 26;15(1):9244
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis.
Tan L, Fan Y, Xu X, Zhang T, Cao X, Zhang C, Liang J, Hou Y, Dou H
Arthritis research & therapy 2024 Oct 23;26(1):183
Arthritis research & therapy 2024 Oct 23;26(1):183
Morphine-induced hyperalgesia impacts small extracellular vesicle miRNA composition and function.
Reddy D, Lin Z, Ramanathan S, Luo X, Pande R, Tian Y, Side C, Barker JM, Sacan A, Blendy JA, Ajit SK
bioRxiv : the preprint server for biology 2024 Oct 21;
bioRxiv : the preprint server for biology 2024 Oct 21;
Functional cardiac consequences of β-adrenergic stress-induced injury in a model of Duchenne muscular dystrophy.
Earl CC, Javier AJ, Richards AM, Markham LW, Goergen CJ, Welc SS
Disease models & mechanisms 2024 Oct 1;17(10)
Disease models & mechanisms 2024 Oct 1;17(10)
Serum apolipoprotein H determines ferroptosis resistance by modulating cellular lipid composition.
He X, Zhang J, Huang M, Wang J, Yang S, Yu X, Xu Y, Yang W
Cell death & disease 2024 Oct 1;15(10):718
Cell death & disease 2024 Oct 1;15(10):718
Arginine deprivation/citrulline augmentation with ADI-PEG20 as novel therapy for complications in type 2 diabetes.
Abdelrahman AA, Sandow PV, Wang J, Xu Z, Rojas M, Bomalaski JS, Lemtalsi T, Caldwell RB, Caldwell RW
Molecular metabolism 2024 Nov;89:102020
Molecular metabolism 2024 Nov;89:102020
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Lu Q, Ma J, Zhao Y, Ding G, Wang Y, Qiao X, Cheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice.
Liu X, Chen P, Wu W, Zhong M, Dong S, Lin H, Dai C, Zhang Z, Lin S, Che C, Xu J, Li C, Li H, Pan X, Chen Z, Chen X, Ye ZC
Life sciences 2024 Nov 15;357:123085
Life sciences 2024 Nov 15;357:123085
AGR2-mediated unconventional secretion of 14-3-3ε and α-actinin-4, responsive to ER stress and autophagy, drives chemotaxis in canine mammary tumor cells.
Yuan SH, Wu CC, Wang YC, Chan XY, Chu HW, Yang Y, Liu HP
Cellular & molecular biology letters 2024 May 31;29(1):84
Cellular & molecular biology letters 2024 May 31;29(1):84
Lipotoxic hepatocyte derived LIMA1 enriched small extracellular vesicles promote hepatic stellate cells activation via inhibiting mitophagy.
Li S, Yang F, Cheng F, Zhu L, Yan Y
Cellular & molecular biology letters 2024 May 31;29(1):82
Cellular & molecular biology letters 2024 May 31;29(1):82
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Su Q, Su C, Zhang Y, Guo Y, Liu Y, Liu Y, Yong VW, Xue M
International immunopharmacology 2024 May 10;132:111962
International immunopharmacology 2024 May 10;132:111962
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
Chen Y, Zhang YH, Li J, Shi L, Xie JC, Han X, Chen YT, Xiang M, Li BW, Xing HR, Wang JY
Cancer gene therapy 2024 Mar;31(3):364-375
Cancer gene therapy 2024 Mar;31(3):364-375
Blood-based CNS regionally and neuronally enriched extracellular vesicles carrying pTau217 for Alzheimer's disease diagnosis and differential diagnosis.
Guo Z, Tian C, Shi Y, Song XR, Yin W, Tao QQ, Liu J, Peng GP, Wu ZY, Wang YJ, Zhang ZX, Zhang J
Acta neuropathologica communications 2024 Mar 5;12(1):38
Acta neuropathologica communications 2024 Mar 5;12(1):38
Millimeter-scale magnetic implants paired with a fully integrated wearable device for wireless biophysical and biochemical sensing.
Wan J, Nie Z, Xu J, Zhang Z, Yao S, Xiang Z, Lin X, Lu Y, Xu C, Zhao P, Wang Y, Zhang J, Wang Y, Zhang S, Wang J, Man W, Zhang M, Han M
Science advances 2024 Mar 22;10(12):eadm9314
Science advances 2024 Mar 22;10(12):eadm9314
Generation of Highly Functional Hepatocyte-like Organoids from Human Adipose-Derived Mesenchymal Stem Cells Cultured with Endothelial Cells.
Chen S, Saito Y, Waki Y, Ikemoto T, Teraoku H, Yamada S, Morine Y, Shimada M
Cells 2024 Mar 20;13(6)
Cells 2024 Mar 20;13(6)
Apolipoprotein O modulates cholesterol metabolism via NRF2/CYB5R3 independent of LDL receptor.
Chen J, Hu J, Guo X, Yang Y, Qin D, Tang X, Huang Z, Wang F, Hu D, Peng D, Yu B
Cell death & disease 2024 Jun 3;15(6):389
Cell death & disease 2024 Jun 3;15(6):389
Superporous sponge prepared by secondary network compaction with enhanced permeability and mechanical properties for non-compressible hemostasis in pigs.
Jiang T, Chen S, Xu J, Zhang Y, Fu H, Ling Q, Xu Y, Chu X, Wang R, Hu L, Li H, Huang W, Bian L, Zhao P, Wei F
Nature communications 2024 Jun 27;15(1):5460
Nature communications 2024 Jun 27;15(1):5460
Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis.
Ogino N, Leite MF, Guerra MT, Kruglov E, Asashima H, Hafler DA, Ito T, Pereira JP, Peiffer BJ, Sun Z, Ehrlich BE, Nathanson MH
The Journal of clinical investigation 2024 Jun 25;134(16)
The Journal of clinical investigation 2024 Jun 25;134(16)
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
Yu T, Ma X, Cheng Y, Wang Z, Zhang G, Ding H, Yin J, Wang Y, Hu S
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
Investigation of ferroptosis-associated molecular subtypes and immunological characteristics in lupus nephritis based on artificial neural network learning.
Zhang L, Yan Q, Lin M, He J, Tian J, Chen Z, Hong F
Arthritis research & therapy 2024 Jul 3;26(1):126
Arthritis research & therapy 2024 Jul 3;26(1):126
A PNPLA3-Deficient iPSC-Derived Hepatocyte Screen Identifies Pathways to Potentially Reduce Steatosis in Metabolic Dysfunction-Associated Fatty Liver Disease.
Doueiry C, Kappler CS, Martinez-Morant C, Duncan SA
International journal of molecular sciences 2024 Jul 2;25(13)
International journal of molecular sciences 2024 Jul 2;25(13)
Apomorphine Suppresses the Progression of Steatohepatitis by Inhibiting Ferroptosis.
Maeda H, Miura K, Aizawa K, Bat-Erdene O, Sashikawa-Kimura M, Noguchi E, Watanabe M, Yamada N, Osaka H, Morimoto N, Yamamoto H
Antioxidants (Basel, Switzerland) 2024 Jul 2;13(7)
Antioxidants (Basel, Switzerland) 2024 Jul 2;13(7)
Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury.
Shahror RA, Shosha E, Morris C, Wild M, Mu S, Csanyi G, Boerma M, Rusch NJ, Fouda AY
Journal of neuroinflammation 2024 Jul 12;21(1):170
Journal of neuroinflammation 2024 Jul 12;21(1):170
A novel lung cancer stem cell extracellular vesicles lncRNA ROLLCSC modulate non-stemness cancer cell plasticity through miR-5623-3p and miR-217-5p targeting lipid metabolism.
Zhang YH, Chen Y, Shi L, Han X, Xie JC, Chen Y, Xiang M, Li BW, Li J, Xing HR, Wang JY
International journal of biological macromolecules 2024 Jan;256(Pt 2):128412
International journal of biological macromolecules 2024 Jan;256(Pt 2):128412
IFITM3 overexpression reverses insufficient healing benefits of small extracellular vesicles from high-fat-diet BMSCs in sepsis via the HMGB1 pathway.
Cui J, Chen C, Zhou X, Shan W, Jian Y, Feng L, Li P, Sun Y, Yi W
International immunopharmacology 2024 Jan 5;126:111250
International immunopharmacology 2024 Jan 5;126:111250
Manipulating HGF signaling reshapes the cirrhotic liver niche and fills a therapeutic gap in regeneration mediated by transplanted stem cells.
Zhang H, Chen Q, Hu D, Lai J, Yan M, Wu Z, Yang Z, Zheng S, Liu W, Zhang L, Bai L
Experimental cell research 2024 Jan 1;434(1):113867
Experimental cell research 2024 Jan 1;434(1):113867
Single-cell transcriptome analysis of aging mouse liver.
Lin Y, Li Y, Liang G, Yang X, Yang J, Hu Q, Sun J, Zhang C, Fang H, Liu A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23473
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb 29;38(4):e23473
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
Wang Z, Bi M, Zhe X, Wang X, Dai B, Han X, Ren B, Liang H, Liu D
Cell death discovery 2024 Feb 22;10(1):95
Cell death discovery 2024 Feb 22;10(1):95
Inflammatory pain resolution by mouse serum-derived small extracellular vesicles.
Lin Z, Luo X, Wickman JR, Reddy D, Pande R, Tian Y, Triana V, Lee J, Furdui CM, Pink D, Sacan A, Ajit SK
bioRxiv : the preprint server for biology 2024 Feb 18;
bioRxiv : the preprint server for biology 2024 Feb 18;
S-Nitrosylation of NOTCH1 Regulates Mesenchymal Stem Cells Differentiation Into Hepatocyte-Like Cells by Inhibiting Notch Signalling Pathway.
Wang X, Xu Y, Wang Y, Tang X, Zhou X, Lu W, Chen W, Li L, Zhou L, Ye J
Journal of cellular and molecular medicine 2024 Dec;28(23):e70274
Journal of cellular and molecular medicine 2024 Dec;28(23):e70274
Integrated metabolomics and network pharmacology analysis to reveal the protective effect of Complanatoside A on nonalcoholic fatty liver disease.
Jiang S, Fan X, Hua J, Liu S, Feng Y, Shao D, Shen Y, Wang Z, Yan X, Wang J
European journal of pharmacology 2024 Dec 15;985:177074
European journal of pharmacology 2024 Dec 15;985:177074
Mice Hepatic Organoids for Modeling Nonalcoholic Fatty Liver Disease and Drug Response.
Zhou Z, Zheng X, Xie M, Lin Z, Du F, Shi X, Li R
Stem cells and development 2024 Aug;33(15-16):387-398
Stem cells and development 2024 Aug;33(15-16):387-398
C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport.
Wu Y, Zheng W, Xu G, Zhu L, Li Z, Chen J, Wang L, Chen S
Cell death and differentiation 2024 Aug;31(8):1070-1084
Cell death and differentiation 2024 Aug;31(8):1070-1084
Intimomedial tears of the aorta heal by smooth muscle cell-mediated fibrosis without atherosclerosis.
Hassab AH, Hur DJ, Vallabhajosyula P, Tellides G, Assi R
JCI insight 2024 Apr 9;9(9)
JCI insight 2024 Apr 9;9(9)
Western Blot Protocols for Analysis of CCN Proteins and Fragments in Exosomes, Vesicle-Free Fractions, and Cells.
Ono K, Okusha Y, Tran MT, Umemori K, Eguchi T
Methods in molecular biology (Clifton, N.J.) 2023;2582:39-57
Methods in molecular biology (Clifton, N.J.) 2023;2582:39-57
Low-dose lipopolysaccharide inducing continuous and obvious increase in urinary protein in hyperglycemic rats and the underlying mechanism.
Wang M, Gong Q, Zha C, Xu S, Yu D, Huang T, Feng Y, Sun H, Li J
PloS one 2023;18(7):e0288876
PloS one 2023;18(7):e0288876
Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.
Wang J, Tan Y, Dai Y, Hu K, Tan X, Jiang S, Li G, Zhang X, Kang L, Wang X, Xu B
International journal of nanomedicine 2023;18:5495-5510
International journal of nanomedicine 2023;18:5495-5510
Mechanism of Wuzhuyu decoction on alcohol-induced gastric ulcers using integrated network analysis and metabolomics.
Wang X, Chen L, Chang L, He Y, He T, Wang R, Wei S, Jing M, Zhou X, Li H, Zhao Y
Frontiers in pharmacology 2023;14:1308995
Frontiers in pharmacology 2023;14:1308995
Generation and characterization of an inducible renal proximal tubule-specific CreERT2 mouse.
Liang S, Wang Y, Kang M, Deng J, Chen L, Hong X, Hou FF, Zhang F
Frontiers in cell and developmental biology 2023;11:1171637
Frontiers in cell and developmental biology 2023;11:1171637
Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injury.
Li Y, Xu J, Chen W, Wang X, Zhao Z, Li Y, Zhang L, Jiao J, Yang Q, Ding Q, Yang P, Wei L, Chen Y, Chen Y, Ruan XZ, Zhao L
Autophagy 2023 Sep;19(9):2504-2519
Autophagy 2023 Sep;19(9):2504-2519
miR-32-5p induces hepatic steatosis and hyperlipidemia by triggering de novo lipogenesis.
Wang YD, Wu LL, Mai YN, Wang K, Tang Y, Wang QY, Li JY, Jiang LY, Liao ZZ, Hu C, Wang YY, Liu JJ, Liu JH, Xiao XH
Metabolism: clinical and experimental 2023 Sep;146:155660
Metabolism: clinical and experimental 2023 Sep;146:155660
MDIG-mediated H3K9me3 demethylation upregulates Myc by activating OTX2 and facilitates liver regeneration.
Du J, Liao W, Wang H, Hou G, Liao M, Xu L, Huang J, Yuan K, Chen X, Zeng Y
Signal transduction and targeted therapy 2023 Sep 15;8(1):351
Signal transduction and targeted therapy 2023 Sep 15;8(1):351
Inhibition of free heme-catalyzed Fenton-like reaction prevents non-alcoholic fatty liver disease by hepatocyte-targeted hydrogen delivery.
Zhao M, Jin Z, Xia C, Chen S, Zeng L, Qin S, He Q
Biomaterials 2023 Oct;301:122230
Biomaterials 2023 Oct;301:122230
Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure.
Jin Y, Zhang J, Xu Y, Yi K, Li F, Zhou H, Wang H, Chan HF, Lao YH, Lv S, Tao Y, Li M
Bioactive materials 2023 Oct;28:112-131
Bioactive materials 2023 Oct;28:112-131
Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes.
Song Z, Lin S, Wu X, Ren X, Wu Y, Wen H, Qian B, Lin H, Huang Y, Zhao C, Wang N, Huang Y, Peng B, Li X, Peng H, Shen S
Hepatology international 2023 Oct;17(5):1300-1317
Hepatology international 2023 Oct;17(5):1300-1317
Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner.
Zhang Y, Liu X, Sun K, Luo Y, Yang J, Li A, Kiupel M, Fenske S, Biel M, Mi QS, Wang H, Xiao H
Cell reports 2023 Oct 31;42(10):113157
Cell reports 2023 Oct 31;42(10):113157
Manganese regulation of COPII condensation controls circulating lipid homeostasis.
Wang X, Huang R, Wang Y, Zhou W, Hu Y, Yao Y, Cheng K, Li X, Xu B, Zhang J, Xu Y, Zeng F, Zhu Y, Chen XW
Nature cell biology 2023 Nov;25(11):1650-1663
Nature cell biology 2023 Nov;25(11):1650-1663
Urinary SPP1 has potential as a non-invasive diagnostic marker for focal segmental glomerulosclerosis.
Ye Q, Xu G, Xue C, Pang S, Xie B, Huang G, Li H, Chen X, Yang R, Li W
FEBS open bio 2023 Nov;13(11):2061-2080
FEBS open bio 2023 Nov;13(11):2061-2080
Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice.
Hu S, Zhu Y, Zhao X, Li R, Shao G, Gong D, Hu C, Liu H, Xu K, Liu C, Xu M, Zhao Z, Li T, Hu Z, Shao M, Liu J, Li X, Wu H, Li J, Xu Y
Developmental cell 2023 Nov 6;58(21):2326-2337.e5
Developmental cell 2023 Nov 6;58(21):2326-2337.e5
Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy.
Cui D, Wang Z, Dang Q, Wang J, Qin J, Song J, Zhai X, Zhou Y, Zhao L, Lu G, Liu H, Liu G, Liu R, Shao C, Zhang X, Liu Z
Nature communications 2023 Nov 3;14(1):7032
Nature communications 2023 Nov 3;14(1):7032
PTEN/AKT and Wnt/β-catenin signaling pathways regulate the proliferation of Lgr5+ cells in liver cancer.
He J, Han J, Lin K, Wang J, Li G, Li X, Gao Y
Biochemical and biophysical research communications 2023 Nov 26;683:149117
Biochemical and biophysical research communications 2023 Nov 26;683:149117
Chemical modification of AAV9 capsid with N-ethyl maleimide alters vector tissue tropism.
Mulcrone PL, Lam AK, Frabutt D, Zhang J, Chrzanowski M, Herzog RW, Xiao W
Scientific reports 2023 May 25;13(1):8436
Scientific reports 2023 May 25;13(1):8436
Salvianolic acid A attenuates inflammation-mediated atherosclerosis by suppressing GRP78 secretion of endothelial cells.
Fan X, Zhang L, La X, Tian J, Israr G, Li A, Wu C, An Y, Li S, Dong X, Li Z
Journal of ethnopharmacology 2023 May 23;308:116219
Journal of ethnopharmacology 2023 May 23;308:116219
Herpetin Promotes Bone Marrow Mesenchymal Stem Cells to Alleviate Carbon Tetrachloride-Induced Acute Liver Injury in Mice.
Ding Y, Tan R, Gu J, Gong P
Molecules (Basel, Switzerland) 2023 May 1;28(9)
Molecules (Basel, Switzerland) 2023 May 1;28(9)
BM-MSCs overexpressing the Numb enhance the therapeutic effect on cholestatic liver fibrosis by inhibiting the ductular reaction.
Xu YN, Xu W, Zhang X, Wang DY, Zheng XR, Liu W, Chen JM, Chen GF, Liu CH, Liu P, Mu YP
Stem cell research & therapy 2023 Mar 20;14(1):45
Stem cell research & therapy 2023 Mar 20;14(1):45
HPF Modulates the Differentiation of BMSCs into HLCs and Promotes the Recovery of Acute Liver Injury in Mice.
Yang B, Luo QL, Wang N, Hu YT, Zheng WX, Li H, Maierziya M, Gu J, Wang Q
International journal of molecular sciences 2023 Mar 16;24(6)
International journal of molecular sciences 2023 Mar 16;24(6)
Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy.
Shan S, Liu F, Ford E, Caldwell RB, Narayanan SP, Somanath PR
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114714
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114714
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Tissue-Engineered Hepatocyte Sheets Supplemented with Adipose-Derived Stem Cells.
Suzushino S, Sato N, Ishigame T, Okada R, Kofunato Y, Watanabe J, Muto M, Tsukida S, Nishimagi A, Kimura T, Kenjo A, Waguri S, Marubashi S
Tissue engineering. Part A 2023 Jul;29(13-14):384-396
Tissue engineering. Part A 2023 Jul;29(13-14):384-396
A Scd1-mediated metabolic alteration participates in liver responses to low-dose bavachin.
Shen P, Bai ZJ, Zhou L, Wang NN, Ni ZX, Sun DZ, Huang CS, Hu YY, Xiao CR, Zhou W, Zhang BL, Gao Y
Journal of pharmaceutical analysis 2023 Jul;13(7):806-816
Journal of pharmaceutical analysis 2023 Jul;13(7):806-816
Small extracellular vesicles derived from human adipose-derived mesenchymal stromal cells cultured in a new chemically-defined contaminate-free media exhibit enhanced biological and therapeutic effects on human chondrocytes in vitro and in a mouse osteoarthritis model.
Hanai H, Hart DA, Jacob G, Shimomura K, Ando W, Yoshioka Y, Ochiya T, Nakagawa S, Nakamura M, Okada S, Nakamura N
Journal of extracellular vesicles 2023 Jul;12(7):e12337
Journal of extracellular vesicles 2023 Jul;12(7):e12337
Caveolin-1 ameliorates acetaminophen-aggravated inflammatory damage and lipid deposition in non-alcoholic fatty liver disease via the ROS/TXNIP/NLRP3 pathway.
Jiang X, Li Y, Fu D, You T, Wu S, Xin J, Wen J, Huang Y, Hu C
International immunopharmacology 2023 Jan;114:109558
International immunopharmacology 2023 Jan;114:109558
Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways.
Liu C, Tian Q, Wang J, He P, Han S, Guo Y, Yang C, Wang G, Wei H, Li M
Molecular neurobiology 2023 Feb;60(2):460-479
Molecular neurobiology 2023 Feb;60(2):460-479
Integrated omics landscape of hepatocellular carcinoma suggests proteomic subtypes for precision therapy.
Xing X, Hu E, Ouyang J, Zhong X, Wang F, Liu K, Cai L, Zhou Y, Wang Y, Chen G, Li Z, Wu L, Liu X
Cell reports. Medicine 2023 Dec 19;4(12):101315
Cell reports. Medicine 2023 Dec 19;4(12):101315
Modeling Colorectal Cancer-Induced Liver Portal Vein Microthrombus on a Hepatic Lobule Chip.
Du X, Zou R, Du K, Huang D, Miao C, Qiu B, Ding W, Li C
ACS applied materials & interfaces 2023 Dec 13;15(49):56859-56868
ACS applied materials & interfaces 2023 Dec 13;15(49):56859-56868
Hepatocyte-derived MASP1-enriched small extracellular vesicles activate HSCs to promote liver fibrosis.
Liu X, Tan S, Liu H, Jiang J, Wang X, Li L, Wu B
Hepatology (Baltimore, Md.) 2023 Apr 1;77(4):1181-1197
Hepatology (Baltimore, Md.) 2023 Apr 1;77(4):1181-1197
Fenofibrate enhances lipid deposition via modulating PPARγ, SREBP-1c, and gut microbiota in ob/ob mice fed a high-fat diet.
Zhang Y, Jia XB, Liu YC, Yu WQ, Si YH, Guo SD
Frontiers in nutrition 2022;9:971581
Frontiers in nutrition 2022;9:971581
ATP5O Hypo-crotonylation Caused by HDAC2 Hyper-Phosphorylation Is a Primary Detrimental Factor for Downregulated Phospholipid Metabolism under Chronic Stress.
Chen LJ, Tu ZY, Wang Y, He YH, Wang X, Tao SZ, Xu YY, Li CR, Wang RL, Yang ZX, Sun J, Ma X, Zhang D
Research (Washington, D.C.) 2022;2022:9834963
Research (Washington, D.C.) 2022;2022:9834963
GLP-1 RA Improves Diabetic Retinopathy by Protecting the Blood-Retinal Barrier through GLP-1R-ROCK-p-MLC Signaling Pathway.
Wei L, Mo W, Lan S, Yang H, Huang Z, Liang X, Li L, Xian J, Xie X, Qin Y, Lin F, Luo Z
Journal of diabetes research 2022;2022:1861940
Journal of diabetes research 2022;2022:1861940
Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.
Bai F, Duan J, Yang D, Lai X, Zhu X, He X, Hu A
Stem cell research & therapy 2022 Sep 8;13(1):468
Stem cell research & therapy 2022 Sep 8;13(1):468
Systemic Administration of Pegylated Arginase-1 Attenuates the Progression of Diabetic Retinopathy.
Abdelrahman AA, Bunch KL, Sandow PV, Cheng PN, Caldwell RB, Caldwell RW
Cells 2022 Sep 16;11(18)
Cells 2022 Sep 16;11(18)
Pore-forming protein βγ-CAT promptly responses to fasting with capacity to deliver macromolecular nutrients.
Shi ZH, Zhao Z, Liu LZ, Bian XL, Zhang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22533
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22533
Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models.
Ramani K, Mavila N, Abeynayake A, Tomasi ML, Wang J, Matsuda M, Seki E
eLife 2022 Oct 4;11
eLife 2022 Oct 4;11
A novel anti-TNF-α drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis.
Oyama S, Ebina K, Etani Y, Hirao M, Kyuuma M, Fujii Y, Iwata K, Ogawa B, Hasegawa T, Kawano S, Nakanishi Y, Okada S, Nakata K
Scientific reports 2022 Oct 27;12(1):18102
Scientific reports 2022 Oct 27;12(1):18102
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
Zhou GP, Li SP, Jiang YZ, Sun J, Tan YL, Zeng ZG, Wei L, Qu W, Sun LY, Zhu ZJ
Journal of translational medicine 2022 Oct 20;20(1):479
Journal of translational medicine 2022 Oct 20;20(1):479
Blood plasma derived extracellular vesicles (BEVs): particle purification liquid chromatography (PPLC) and proteomic analysis reveals BEVs as a potential minimally invasive tool for predicting response to breast cancer treatment.
Alvarez FA, Kaddour H, Lyu Y, Preece C, Cohen J, Baer L, Stopeck AT, Thompson P, Okeoma CM
Breast cancer research and treatment 2022 Nov;196(2):423-437
Breast cancer research and treatment 2022 Nov;196(2):423-437
SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.
Xu W, Du X, Li J, Zhang Z, Ma X, Luo D, Xiao M, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969
Microglia secrete miR-146a-5p-containing exosomes to regulate neurogenesis in depression.
Fan C, Li Y, Lan T, Wang W, Long Y, Yu SY
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1300-1314
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1300-1314
Constructing vascularized hepatic tissue by cell-assembled viscous tissue sedimentation method and its application for vascular toxicity assessment.
Naito Y, Yoshinouchi Y, Sorayama Y, Kohara H, Kitano S, Irie S, Matsusaki M
Acta biomaterialia 2022 Mar 1;140:275-288
Acta biomaterialia 2022 Mar 1;140:275-288
Prenatal glucocorticoid administration accelerates the maturation of fetal rat hepatocytes.
Kobayashi T, Takeba Y, Ohta Y, Ootaki M, Kida K, Watanabe M, Iiri T, Matsumoto N
Molecular biology reports 2022 Jul;49(7):5831-5842
Molecular biology reports 2022 Jul;49(7):5831-5842
Deletion of p38γ attenuates ethanol consumption- and acetaminophen-induced liver injury in mice through promoting Dlg1.
Hu S, Yao Y, Wei ZY, Wang SX, Wu YC, Hu Y, Yang CC, Min JL, Li LY, Zhou H, Yang JF, Li J, Xu T
Acta pharmacologica Sinica 2022 Jul;43(7):1733-1748
Acta pharmacologica Sinica 2022 Jul;43(7):1733-1748
Letter to the Editor: False Hypercortisolemia Due to Abnormal Albumin-Cortisol Binding in a Patient with Familial Dysalbuminemic Hyperthyroxinemia.
Chiba K, Kameda H, Miya A, Nomoto H, Cho KY, Nakamura A, Jin S, Matoba K, Miyoshi H, Atsumi T
Thyroid : official journal of the American Thyroid Association 2022 Feb;32(2):219-220
Thyroid : official journal of the American Thyroid Association 2022 Feb;32(2):219-220
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles.
Li YJ, Liu RP, Ding MN, Zheng Q, Wu JZ, Xue XY, Gu YQ, Ma BN, Cai YJ, Li S, Lin S, Zhang LY, Li X
Acta pharmacologica Sinica 2022 Aug;43(8):2026-2041
Acta pharmacologica Sinica 2022 Aug;43(8):2026-2041
Expression and activation of the ketone body receptor HCAR2/GPR109A promotes preservation of retinal endothelial cell barrier function.
Abdelrahman AA, Powell FL, Jadeja RN, Jones MA, Thounaojam MC, Bartoli M, Al-Shabrawey M, Martin PM
Experimental eye research 2022 Aug;221:109129
Experimental eye research 2022 Aug;221:109129
A single-cell atlas of the multicellular ecosystem of primary and metastatic hepatocellular carcinoma.
Lu Y, Yang A, Quan C, Pan Y, Zhang H, Li Y, Gao C, Lu H, Wang X, Cao P, Chen H, Lu S, Zhou G
Nature communications 2022 Aug 6;13(1):4594
Nature communications 2022 Aug 6;13(1):4594
Universal Markers for hiPSCs Residue Detection.
Shi H, Feng T, Wang R, Wu L, Gu Y
Frontiers in bioscience (Landmark edition) 2022 Aug 11;27(8):239
Frontiers in bioscience (Landmark edition) 2022 Aug 11;27(8):239
Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes.
Kojima H, Yagi H, Kushige H, Toda Y, Takayama K, Masuda S, Morisaku T, Tsuchida T, Kuroda K, Hirukawa K, Inui J, Nishi K, Nakano Y, Tanaka M, Hori S, Hasegawa Y, Abe Y, Kitago M, Adachi S, Tomi M, Matsuura K, Mizuguchi H, Kitagawa Y
Cells 2022 Apr 7;11(8)
Cells 2022 Apr 7;11(8)
Profiling Blood Serum Extracellular Vesicles in Plaque Psoriasis and Psoriatic Arthritis Patients Reveals Potential Disease Biomarkers.
Lättekivi F, Guljavina I, Midekessa G, Viil J, Heath PR, Bæk R, Jørgensen MM, Andronowska A, Kingo K, Fazeli A
International journal of molecular sciences 2022 Apr 4;23(7)
International journal of molecular sciences 2022 Apr 4;23(7)
Establishment of Functional Liver Spheroids From Human Hepatocyte-Derived Liver Progenitor-Like Cells for Cell Therapy.
Liu WM, Zhou X, Chen CY, Lv DD, Huang WJ, Peng Y, Wu HP, Chen Y, Tang D, Guo LN, Wang XL, Zhang HD, Liu XH, Yang LQ, Yu WF, Yan HX
Frontiers in bioengineering and biotechnology 2021;9:738081
Frontiers in bioengineering and biotechnology 2021;9:738081
The Cordyceps militaris-Derived Polysaccharide CM1 Alleviates Atherosclerosis in LDLR((-/-)) Mice by Improving Hyperlipidemia.
Yin F, Lin P, Yu WQ, Shen N, Li Y, Guo SD
Frontiers in molecular biosciences 2021;8:783807
Frontiers in molecular biosciences 2021;8:783807
PTEN-mediated AKT/β-catenin signaling enhances the proliferation and expansion of Lgr5+ hepatocytes.
Han J, Lin K, Zhang X, Yan L, Chen Y, Chen H, Liu J, Liu J, Wu Y
International journal of biological sciences 2021;17(3):861-868
International journal of biological sciences 2021;17(3):861-868
An Albumin-Binding Domain Peptide Confers Enhanced Immunoprotection Against Viral Myocarditis by CVB3 VP1 Vaccine.
Gao Y, Yue Y, Xiong S
Frontiers in immunology 2021;12:666594
Frontiers in immunology 2021;12:666594
The combined induction of liver progenitor cells and the suppression of stellate cells by small molecules reverts chronic hepatic dysfunction.
Huang WJ, Zhou X, Fu GB, Ding M, Wu HP, Zeng M, Zhang HD, Xu LY, Gao Y, Wang HY, Yan HX
Theranostics 2021;11(11):5539-5552
Theranostics 2021;11(11):5539-5552
Circulating microRNAs from the mouse tibia fracture model reflect the signature from patients with complex regional pain syndrome.
Wickman JR, Luo X, Li W, Jean-Toussaint R, Sahbaie P, Sacan A, Clark JD, Ajit SK
Pain reports 2021 Sep-Oct;6(3):e950
Pain reports 2021 Sep-Oct;6(3):e950
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Du K, Li S, Li C, Li P, Miao C, Luo T, Qiu B, Ding W
Acta biomaterialia 2021 Oct 15;134:228-239
Acta biomaterialia 2021 Oct 15;134:228-239
Changes in the hepatic differentiation potential of human mesenchymal stem cells aged in vitro.
Luo S, Xiao S, Ai Y, Wang B, Wang Y
Annals of translational medicine 2021 Nov;9(21):1628
Annals of translational medicine 2021 Nov;9(21):1628
Hypoxia Preconditioning Promotes the Proliferation and Migration of Human Urine-Derived Stem Cells in Chronically Injured Liver of Mice by Upregulating CXCR4.
Hu C, He Y, Liu D, Zhao L, Fang S, Tan B, Dong S, Wang Y, He T, Bi Y
Stem cells and development 2021 May 15;30(10):526-536
Stem cells and development 2021 May 15;30(10):526-536
In vivo self-assembled small RNAs as a new generation of RNAi therapeutics.
Fu Z, Zhang X, Zhou X, Ur-Rehman U, Yu M, Liang H, Guo H, Guo X, Kong Y, Su Y, Ye Y, Hu X, Cheng W, Wu J, Wang Y, Gu Y, Lu SF, Wu D, Zen K, Li J, Yan C, Zhang CY, Chen X
Cell research 2021 Jun;31(6):631-648
Cell research 2021 Jun;31(6):631-648
The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation.
Zhang W, Zhangyuan G, Wang F, Jin K, Shen H, Zhang L, Yuan X, Wang J, Zhang H, Yu W, Huang R, Xu X, Yin Y, Zhong G, Lin A, Sun B
Immunity 2021 Jun 8;54(6):1168-1185.e8
Immunity 2021 Jun 8;54(6):1168-1185.e8
Assessment of long-term functional maintenance of primary human hepatocytes to predict drug-induced hepatoxicity in vitro.
Chen Y, Tang D, Wu H, Wu Y, Yuan T, Zhang H, Jiao Y, Yu W, Yan H
Archives of toxicology 2021 Jul;95(7):2431-2442
Archives of toxicology 2021 Jul;95(7):2431-2442
Functional hit 1 (FH1)-based rapid and efficient generation of functional hepatocytes from human mesenchymal stem cells: a novel strategy for hepatic differentiation.
Luo S, Ai Y, Xiao S, Wang B, Wang Y
Annals of translational medicine 2021 Jul;9(13):1087
Annals of translational medicine 2021 Jul;9(13):1087
Exosomes derived from astrocytes after oxygen-glucose deprivation promote differentiation and migration of oligodendrocyte precursor cells in vitro.
Xu Y, Tian Y, Wang Y, Xu L, Song G, Wu Q, Wang W, Xie M
Molecular biology reports 2021 Jul;48(7):5473-5484
Molecular biology reports 2021 Jul;48(7):5473-5484
Enterically derived high-density lipoprotein restrains liver injury through the portal vein.
Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ
Science (New York, N.Y.) 2021 Jul 23;373(6553)
Science (New York, N.Y.) 2021 Jul 23;373(6553)
On-Chip Construction of Liver Lobules with Self-Assembled Perfusable Hepatic Sinusoid Networks.
Ya S, Ding W, Li S, Du K, Zhang Y, Li C, Liu J, Li F, Li P, Luo T, He L, Xu A, Gao D, Qiu B
ACS applied materials & interfaces 2021 Jul 21;13(28):32640-32652
ACS applied materials & interfaces 2021 Jul 21;13(28):32640-32652
Proximity Proteomics Has Potential for Extracellular Vesicle Identification.
Kaneda H, Ida Y, Kuwahara R, Sato I, Nakano T, Tokuda H, Sato T, Murakoshi T, Honke K, Kotani N
Journal of proteome research 2021 Jul 2;20(7):3519-3531
Journal of proteome research 2021 Jul 2;20(7):3519-3531
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Zhang Y, Han X, Nie G
Nature protocols 2021 Jan;16(1):405-430
Nature protocols 2021 Jan;16(1):405-430
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells.
Li M, Sun P, Dong K, Xin Y, TaiLulu A, Li Q, Sun J, Peng M, Shi P
Archives of pharmacal research 2021 Feb;44(2):194-204
Archives of pharmacal research 2021 Feb;44(2):194-204
Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1.
Deng Y, Tong J, Shi W, Tian Z, Yu B, Tang J
Annals of medicine 2021 Dec;53(1):1129-1141
Annals of medicine 2021 Dec;53(1):1129-1141
A Novel Mouse Model for Cerebral Venous Sinus Thrombosis.
Bourrienne MC, Loyau S, Benichi S, Gay J, Solo-Nomenjanahary M, Journé C, Di Meglio L, Freiherr von Seckendorff A, Desilles JP, Ho-Tin-Noé B, Ajzenberg N, Mazighi M
Translational stroke research 2021 Dec;12(6):1055-1066
Translational stroke research 2021 Dec;12(6):1055-1066
Impaired Glucocorticoid Receptor Signaling Aggravates Lung Injury after Hemorrhagic Shock.
Preuss JM, Burret U, Gröger M, Kress S, Scheuerle A, Möller P, Tuckermann JP, Wepler M, Vettorazzi S
Cells 2021 Dec 30;11(1)
Cells 2021 Dec 30;11(1)
Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/-)) hamsters.
Yu WQ, Yin F, Shen N, Lin P, Xia B, Li YJ, Guo SD
Lipids in health and disease 2021 Dec 13;20(1):178
Lipids in health and disease 2021 Dec 13;20(1):178
Hippocampal microglia CD40 mediates NPSLE cognitive dysfunction in mice.
Qiao X, Wang H, Lu L, Chen J, Cheng Q, Guo M, Hou Y, Dou H
Journal of neuroimmunology 2021 Aug 15;357:577620
Journal of neuroimmunology 2021 Aug 15;357:577620
All-trans-retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating autophagy.
Fang S, Hu C, Xu L, Cui J, Tao L, Gong M, Wang Y, He Y, He T, Bi Y
American journal of translational research 2020;12(10):6793-6810
American journal of translational research 2020;12(10):6793-6810
Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development.
Yang M, Liu Q, Huang T, Tan W, Qu L, Chen T, Pan H, Chen L, Liu J, Wong CW, Lu WW, Guan M
Theranostics 2020;10(24):10874-10891
Theranostics 2020;10(24):10874-10891
CRISPR-Cas9-Mediated In Vivo Gene Integration at the Albumin Locus Recovers Hemostasis in Neonatal and Adult Hemophilia B Mice.
Wang Q, Zhong X, Li Q, Su J, Liu Y, Mo L, Deng H, Yang Y
Molecular therapy. Methods & clinical development 2020 Sep 11;18:520-531
Molecular therapy. Methods & clinical development 2020 Sep 11;18:520-531
Isoform 1 of Fibrinogen Alpha Chain Precursor is a Potential Biomarker for Steroid-Induced Osteonecrosis of the Femoral Head.
Liu L, Song J, Li J, Huang N, Yang J, Hu S, Ma R, Wang W
Proteomics. Clinical applications 2020 Nov;14(6):e1900099
Proteomics. Clinical applications 2020 Nov;14(6):e1900099
Microglial activation and responses to vasculature that result from an acute LPS exposure.
Bowyer JF, Sarkar S, Burks SM, Hess JN, Tolani S, O'Callaghan JP, Hanig JP
Neurotoxicology 2020 Mar;77:181-192
Neurotoxicology 2020 Mar;77:181-192
Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice.
Zhao F, Cheng L, Shao Q, Chen Z, Lv X, Li J, He L, Sun Y, Ji Q, Lu P, Ji Y, Ji J
Scientific reports 2020 Mar 6;10(1):4197
Scientific reports 2020 Mar 6;10(1):4197
Myofibroblast induces hepatocyte-to-ductal metaplasia via laminin-ɑvβ6 integrin in liver fibrosis.
Xu T, Lu Z, Xiao Z, Liu F, Chen Y, Wang Z, Zhu S, Song Y
Cell death & disease 2020 Mar 23;11(3):199
Cell death & disease 2020 Mar 23;11(3):199
Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion.
Wang H, Chen H, Jin J, Liu Q, Zhong D, Li G
Life sciences 2020 Jun 15;251:117638
Life sciences 2020 Jun 15;251:117638
An extracorporeal bioartificial liver embedded with 3D-layered human liver progenitor-like cells relieves acute liver failure in pigs.
Li WJ, Zhu XJ, Yuan TJ, Wang ZY, Bian ZQ, Jing HS, Shi X, Chen CY, Fu GB, Huang WJ, Shi YP, Liu Q, Zeng M, Zhang HD, Wu HP, Yu WF, Zhai B, Yan HX
Science translational medicine 2020 Jul 8;12(551)
Science translational medicine 2020 Jul 8;12(551)
Rab27a dependent exosome releasing participated in albumin handling as a coordinated approach to lysosome in kidney disease.
Feng Y, Zhong X, Tang TT, Wang C, Wang LT, Li ZL, Ni HF, Wang B, Wu M, Liu D, Liu H, Tang RN, Liu BC, Lv LL
Cell death & disease 2020 Jul 8;11(7):513
Cell death & disease 2020 Jul 8;11(7):513
Construction of a High-Expression System in Bacillus through Transcriptomic Profiling and Promoter Engineering.
Miao CC, Han LL, Lu YB, Feng H
Microorganisms 2020 Jul 12;8(7)
Microorganisms 2020 Jul 12;8(7)
Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells.
Kwon Y, Nukala SB, Srivastava S, Miyamoto H, Ismail NI, Rehman J, Ong SB, Lee WH, Ong SG
bioRxiv : the preprint server for biology 2020 Jul 1;
bioRxiv : the preprint server for biology 2020 Jul 1;
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.
Kaddour H, Lyu Y, Welch JL, Paromov V, Mandape SN, Sakhare SS, Pandhare J, Stapleton JT, Pratap S, Dash C, Okeoma CM
Molecular & cellular proteomics : MCP 2020 Jan;19(1):78-100
Molecular & cellular proteomics : MCP 2020 Jan;19(1):78-100
Comprehensive study of dexamethasone on albumin biogenesis during normal and pathological renal conditions.
Gong Q, Yin J, Wang M, He L, Lei F, Luo Y, Yang S, Feng Y, Li J, Du L
Pharmaceutical biology 2020 Dec;58(1):1252-1262
Pharmaceutical biology 2020 Dec;58(1):1252-1262
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Su X, Ma X, Xie X, Wu H, Wang L, Feng Y, Yu Z, Liu C, Qi J, Zhu Q
Cell death discovery 2020 Dec 8;6(1):140
Cell death discovery 2020 Dec 8;6(1):140
Cellular, Extracellular and Extracellular Vesicular miRNA Profiles of Pre-Ovulatory Follicles Indicate Signaling Disturbances in Polycystic Ovaries.
Rooda I, Hasan MM, Roos K, Viil J, Andronowska A, Smolander OP, Jaakma Ü, Salumets A, Fazeli A, Velthut-Meikas A
International journal of molecular sciences 2020 Dec 15;21(24)
International journal of molecular sciences 2020 Dec 15;21(24)
The Effect of Matrix Stiffness on Human Hepatocyte Migration and Function-An In Vitro Research.
Xia T, Zhao R, Feng F, Yang L
Polymers 2020 Aug 24;12(9)
Polymers 2020 Aug 24;12(9)
Long-term Production of Glycogen and Hepatic-Derived, Cell-Invasion-Promoting Chemokines by Ultrasound-Driven Hepatic-Differentiated Human Bone Marrow Mesenchymal Stem Cells.
Song L, Constanthin PE, Sun T, Li X, Xia Z, An L, Li F
Radiation research 2020 Apr;193(4):394-405
Radiation research 2020 Apr;193(4):394-405
Imbalance in mitochondrial dynamics induced by low PGC-1α expression contributes to hepatocyte EMT and liver fibrosis.
Zhang L, Zhang Y, Chang X, Zhang X
Cell death & disease 2020 Apr 8;11(4):226
Cell death & disease 2020 Apr 8;11(4):226
Locus Coeruleus Degeneration Induces Forebrain Vascular Pathology in a Transgenic Rat Model of Alzheimer's Disease.
Kelly SC, McKay EC, Beck JS, Collier TJ, Dorrance AM, Counts SE
Journal of Alzheimer's disease : JAD 2019;70(2):371-388
Journal of Alzheimer's disease : JAD 2019;70(2):371-388
Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction.
Wepler M, Preuss JM, Merz T, Hartmann C, Wachter U, McCook O, Vogt J, Kress S, Gröger M, Fink M, Scheuerle A, Möller P, Calzia E, Burret U, Radermacher P, Tuckermann JP, Vettorazzi S
Frontiers in immunology 2019;10:3152
Frontiers in immunology 2019;10:3152
A critical role of VMP1 in lipoprotein secretion.
Morishita H, Zhao YG, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, Okazaki M, Li D, Mizushima N
eLife 2019 Sep 17;8
eLife 2019 Sep 17;8
ATRA induces the differentiation of hepatic progenitor cells by upregulating microRNA-200a.
Hu C, Liang X, Fang S, Xu L, Gong M, Wang Y, Bi Y, Hong S, He Y
In vitro cellular & developmental biology. Animal 2019 Oct;55(9):713-722
In vitro cellular & developmental biology. Animal 2019 Oct;55(9):713-722
Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance.
Gong XM, Li YF, Luo J, Wang JQ, Wei J, Wang JQ, Xiao T, Xie C, Hong J, Ning G, Shi XJ, Li BL, Qi W, Song BL
Nature metabolism 2019 May;1(5):570-583
Nature metabolism 2019 May;1(5):570-583
Blocking CXCR3 with AMG487 ameliorates the blood-retinal barrier disruption in diabetic mice through anti-oxidative.
Wang H, Li J, Zhong P, Wang S, Zhang L, Yang R, Wu D, Chen M, Ji A, Li Y, Wang J
Life sciences 2019 Jul 1;228:198-207
Life sciences 2019 Jul 1;228:198-207
Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells.
Shi Y, Zhou D, Wang B, Zhou D, Shi B
International journal of molecular medicine 2019 Feb;43(2):1021-1032
International journal of molecular medicine 2019 Feb;43(2):1021-1032
Peptidome profiles in melamine diet-induced bladder stones in C57BL/6 mice.
Liu L, Luo M, Xiong X, Zhao L, Wang X, Ni L, Yang J, Huang C
Toxicology and applied pharmacology 2019 Dec 15;385:114786
Toxicology and applied pharmacology 2019 Dec 15;385:114786
Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell.
Ai WL, Dong LY, Wang J, Li ZW, Wang X, Gao J, Wu Y, An W
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3780-3791
Ultrasound Irradiation Combined with Hepatocyte Growth Factor Accelerate the Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells.
Li F, Liu Y, Cai Y, Li X, Bai M, Sun T, Du L
Ultrasound in medicine & biology 2018 May;44(5):1044-1052
Ultrasound in medicine & biology 2018 May;44(5):1044-1052
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Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390
Nature communications 2018 Aug 23;9(1):3390
Yi Guan Jian decoction may enhance hepatic differentiation of bone marrow‑derived mesenchymal stem cells via SDF‑1 in vitro.
Fu LL, Pang BY, Zhu Y, Wang L, Leng AJ, Chen HL
Molecular medicine reports 2017 Sep;16(3):2511-2521
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Fu J, Fujisawa H, Follman B, Liao XH, Dumitrescu AM
Endocrinology 2017 Dec 1;158(12):4317-4330
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Fu L, Pang B, Zhu Y, Wang L, Leng A, Chen H
Evidence-based complementary and alternative medicine : eCAM 2016;2016:7380439
Evidence-based complementary and alternative medicine : eCAM 2016;2016:7380439
miR-706 inhibits the oxidative stress-induced activation of PKCα/TAOK1 in liver fibrogenesis.
Yin R, Guo D, Zhang S, Zhang X
Scientific reports 2016 Nov 23;6:37509
Scientific reports 2016 Nov 23;6:37509
A long non-coding RNA, APOA4-AS, regulates APOA4 expression depending on HuR in mice.
Qin W, Li X, Xie L, Li S, Liu J, Jia L, Dong X, Ren X, Xiao J, Yang C, Zhou Y, Chen Z
Nucleic acids research 2016 Jul 27;44(13):6423-33
Nucleic acids research 2016 Jul 27;44(13):6423-33
A virus-like particle-based connective tissue growth factor vaccine suppresses carbon tetrachloride-induced hepatic fibrosis in mice.
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Scientific reports 2016 Aug 26;6:32155
Scientific reports 2016 Aug 26;6:32155
The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress.
Wang J, Wang S, Li M, Wu D, Liu F, Yang R, Ji S, Ji A, Li Y
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PloS one 2014;9(12):e116453
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Journal of virological methods 2014 Oct;207:29-37
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Journal of virological methods 2014 Jan;195:185-93
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Nature immunology 2013 Aug;14(8):793-803
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Journal of cellular and molecular medicine 2012 Jan;16(1):118-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human blood tissue were subjected to SDS PAGE followed by western blot with 16475-1-AP(ALB antibody) at dilution of 1:10000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16475-1-AP(ALB antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Albumin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Albumin. This antibody recognizes human,mouse,rat antigen. The Albumin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
