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- References [21]
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- Product number
- 20445-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20445-1-AP, RRID:AB_10694439
- Product name
- USP33 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP33 antibody (Cat. #20445-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Involvement of USP33 in ferritinophagy and ferroptosis in endometriosis through the Hippo-YAP pathway.
GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC.
13-Docosenamide Enhances Oligodendrocyte Precursor Cell Differentiation via USP33-Mediated Deubiquitination of CNR1 in Chronic Cerebral Hypoperfusion.
USP33 Regulates DNA Damage Response and Carcinogenesis Through Deubiquitylating and Stabilising p53.
USP15 inhibits hypoxia-induced IL-6 signaling by deubiquitinating and stabilizing MeCP2.
Unveiling the Pharmacological Role of Human Deubiquitinating Enzymes in Temozolomide Response of Glioblastoma Cells.
Lung-Targeted Lipid Nanoparticle-Delivered siUSP33 Attenuates SARS-CoV-2 Replication and Virulence by Promoting Envelope Degradation.
USP11 Exacerbates Radiation-Induced Pneumonitis by Activating Endothelial Cell Inflammatory Response via OTUD5-STING Signaling.
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.
NudC-like protein 2 restrains centriole amplification by stabilizing HERC2.
NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.
The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Li L, You W, Zhang M
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2026 Dec 31;42(1):2589605
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2026 Dec 31;42(1):2589605
GPR34 Stabilized by Deubiquitinase USP8 Suppresses Ferroptosis of ATC.
Yan B, Guo J, Huang M, Li Z, Sun J, Tan H, Lai W, Chang S
Mediators of inflammation 2025;2025:5576056
Mediators of inflammation 2025;2025:5576056
13-Docosenamide Enhances Oligodendrocyte Precursor Cell Differentiation via USP33-Mediated Deubiquitination of CNR1 in Chronic Cerebral Hypoperfusion.
Xu Y, Tan Y, Zhang Z, Chen D, Zhou C, Sun L, Xia S, Bao X, Yang H, Xu Y
Neuroscience bulletin 2025 Nov;41(11):1939-1956
Neuroscience bulletin 2025 Nov;41(11):1939-1956
USP33 Regulates DNA Damage Response and Carcinogenesis Through Deubiquitylating and Stabilising p53.
Zhu Y, Chen Z, Niu K, Li M, Deng Y, Zhang J, Wei D, Wang J, Zhao Y
Cell proliferation 2025 May;58(5):e13793
Cell proliferation 2025 May;58(5):e13793
USP15 inhibits hypoxia-induced IL-6 signaling by deubiquitinating and stabilizing MeCP2.
Zhang ZT, Niu SX, Yu CH, Wan SY, Wang J, Liu CY, Zheng L, Huang K, Zhang Y
The FEBS journal 2025 Jan;292(1):153-167
The FEBS journal 2025 Jan;292(1):153-167
Unveiling the Pharmacological Role of Human Deubiquitinating Enzymes in Temozolomide Response of Glioblastoma Cells.
Yang C, Li Y, Wu Q, Tang J, Chen M, Zhang B, Li B, Qin Y, Huang G, Zhang Y, Zhi F, Liu K
Cell biochemistry and biophysics 2024 Sep;82(3):2183-2193
Cell biochemistry and biophysics 2024 Sep;82(3):2183-2193
Lung-Targeted Lipid Nanoparticle-Delivered siUSP33 Attenuates SARS-CoV-2 Replication and Virulence by Promoting Envelope Degradation.
Zhou Y, Liao Y, Fan L, Wei X, Huang Q, Yang C, Feng W, Wu Y, Gao X, Shen X, Zhou J, Xia Z, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2406211
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(42):e2406211
USP11 Exacerbates Radiation-Induced Pneumonitis by Activating Endothelial Cell Inflammatory Response via OTUD5-STING Signaling.
Tang Y, Wang T, Gu L, Xu Y, Yang Z, Zhu W, Zhang Q, Luo J, Cao J, Jiao Y
International journal of radiation oncology, biology, physics 2024 Jul 15;119(4):1261-1274
International journal of radiation oncology, biology, physics 2024 Jul 15;119(4):1261-1274
USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Zhong B, Zhu Q, Wang L, Wang F, Zheng Y, Lin S, Cheng X
Cell biology international 2023 Aug;47(8):1368-1380
Cell biology international 2023 Aug;47(8):1368-1380
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
Liu M, Yu Z, Yang F, Zhao Z, Zhou M, Wang C, Zhang B, Liang G, Liu X, Shao J
Toxicology 2023 Aug 1;494:153581
Toxicology 2023 Aug 1;494:153581
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
Niu Y, Jiang H, Yin H, Wang F, Hu R, Hu X, Peng B, Shu Y, Li Z, Chen S, Guo F
Diabetes 2022 May 1;71(5):921-933
Diabetes 2022 May 1;71(5):921-933
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
Yuan Y, Miao Y, Ren T, Huang F, Qian L, Chen X, Zuo Y, Zhang HG, He J, Qiao C, Du Q, Wu Q, Zhang W, Zhu C, Xu Y, Wu D, Shi W, Jiang J, Xu G, Zheng H
EMBO reports 2022 Jan 5;23(1):e53466
EMBO reports 2022 Jan 5;23(1):e53466
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses.
Gao W, Rui Y, Li G, Zhai C, Su J, Liu H, Zheng W, Zheng B, Zhang W, Yang Y, Hua S, Yu X
Frontiers in immunology 2021;12:740713
Frontiers in immunology 2021;12:740713
Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.
Culver JA, Mariappan M
The Journal of cell biology 2021 May 3;220(5)
The Journal of cell biology 2021 May 3;220(5)
NudC-like protein 2 restrains centriole amplification by stabilizing HERC2.
Li M, Xu X, Zhang J, Liu M, Wang W, Gao Y, Sun Q, Zhang J, Lu Y, Wang F, Liu W, Zhou T, Yang Y
Cell death & disease 2019 Aug 19;10(9):628
Cell death & disease 2019 Aug 19;10(9):628
NEURL4 regulates the transcriptional activity of tumor suppressor protein p53 by modulating its oligomerization.
Cubillos-Rojas M, Schneider T, Bartrons R, Ventura F, Rosa JL
Oncotarget 2017 Sep 22;8(37):61824-61836
Oncotarget 2017 Sep 22;8(37):61824-61836
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Li X, Song N, Liu L, Liu X, Ding X, Song X, Yang S, Shan L, Zhou X, Su D, Wang Y, Zhang Q, Cao C, Ma S, Yu N, Yang F, Wang Y, Yao Z, Shang Y, Shi L
Nature communications 2017 Mar 31;8:14866
Nature communications 2017 Mar 31;8:14866
Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis.
Cheng Q, Yuan Y, Li L, Guo T, Miao Y, Ren Y, Liu J, Feng Q, Wang X, Zhao P, Zuo Y, Qian L, Zhang L, Zheng H
Experimental cell research 2017 Jul 1;356(1):1-7
Experimental cell research 2017 Jul 1;356(1):1-7
Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.
Liu H, Zhang Q, Li K, Gong Z, Liu Z, Xu Y, Swaney MH, Xiao K, Chen Y
Oncotarget 2016 Dec 6;7(49):81223-81240
Oncotarget 2016 Dec 6;7(49):81223-81240
The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination.
Cubillos-Rojas M, Schneider T, Hadjebi O, Pedrazza L, de Oliveira JR, Langa F, Guénet JL, Duran J, de Anta JM, Alcántara S, Ruiz R, Pérez-Villegas EM, Aguilar-Montilla FJ, Carrión ÁM, Armengol JA, Baple E, Crosby AH, Bartrons R, Ventura F, Rosa JL
Oncotarget 2016 Aug 30;7(35):56083-56106
Oncotarget 2016 Aug 30;7(35):56083-56106
USP33, a new player in lung cancer, mediates Slit-Robo signaling.
Wen P, Kong R, Liu J, Zhu L, Chen X, Li X, Nie Y, Wu K, Wu JY
Protein & cell 2014 Sep;5(9):704-13
Protein & cell 2014 Sep;5(9):704-13
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 20445-1-AP(USP33 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP33 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human USP33. This antibody recognizes human,mouse,rat antigen. The USP33 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
