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DNAJB4
DnaJ heat shock protein family (Hsp40) member B4HLJ1
The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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| Proteintech Group |  13064-1-AP |
9 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| LSBio | LS-C401609 |
Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | 13064-1-AP |
Polyclonal |
WB
ICC
IP
IHC
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| NovoPro Bioscience Inc. | 110095 |
Polyclonal |
WB
EL
ICC
IHC
|
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| antibodies-online | ABIN524489 |
Monoclonal |
WB
EL
IP
|
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