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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12555-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12555-1-AP, RRID:AB_2237745
- Product name
- PrP antibody
- Antibody type
- Polyclonal
- Description
- PrP antibody (Cat. #12555-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Huachansu Injection induces ferroptosis in multiple myeloma through NRF2/HO-1 signaling pathway.
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates.
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi.
PRNP is a pan-cancer prognostic and immunity-related to EMT in colorectal cancer.
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance-mediated oxaliplatin chemoresistance in colorectal cancer.
Exploring the underlying mechanism by transcriptome sequencing in rats with high-voltage electrical burns and the role of iron metabolism.
Copper homeostasis-associated gene PRNP regulates ferroptosis and immune infiltration in breast cancer.
Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma.
Integrative genome analysis identified the KANNO blood group antigen as prion protein.
Muskelin Coordinates PrP(C) Lysosome versus Exosome Targeting and Impacts Prion Disease Progression.
Yang J, Wang F, Hu Z, Liu X, Zhang W, Li C, Wang W, Reaila J, Zhang X, Zhu G, Tian F, Chen B, Zhu X
Journal of ethnopharmacology 2025 Mar 13;343:119454
Journal of ethnopharmacology 2025 Mar 13;343:119454
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates.
Bigi A, Conti AC, Napolitano L, Fusco G, De Simone A, Chiti F, Cascella R, Cecchi C
Cell & bioscience 2025 Dec 9;15(1):166
Cell & bioscience 2025 Dec 9;15(1):166
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi.
Ronzier E, Satpute-Krishnan P
PLoS biology 2025 Apr;23(4):e3003084
PLoS biology 2025 Apr;23(4):e3003084
PRNP is a pan-cancer prognostic and immunity-related to EMT in colorectal cancer.
Chen H, Du Y, Kong Z, Liao X, Li W
Frontiers in cell and developmental biology 2024;12:1391873
Frontiers in cell and developmental biology 2024;12:1391873
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance-mediated oxaliplatin chemoresistance in colorectal cancer.
Xu Y, Hao J, Chen Q, Qin Y, Qin H, Ren S, Sun C, Zhu Y, Shao B, Zhang J, Wang H
Molecular carcinogenesis 2024 Feb;63(2):224-237
Molecular carcinogenesis 2024 Feb;63(2):224-237
Exploring the underlying mechanism by transcriptome sequencing in rats with high-voltage electrical burns and the role of iron metabolism.
Hao J, Lu M, Zhao X, Li C, Ge C, Zhang J, Tu L, Zhang Q
Burns : journal of the International Society for Burn Injuries 2024 Dec;50(9):107226
Burns : journal of the International Society for Burn Injuries 2024 Dec;50(9):107226
Copper homeostasis-associated gene PRNP regulates ferroptosis and immune infiltration in breast cancer.
Lin C, He J, Tong X, Song L
PloS one 2023;18(8):e0288091
PloS one 2023;18(8):e0288091
Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma.
Liu F, Tang L, Li Q, Chen L, Pan Y, Yin Z, He J, Tian J
Frontiers in molecular biosciences 2022;9:962742
Frontiers in molecular biosciences 2022;9:962742
Integrative genome analysis identified the KANNO blood group antigen as prion protein.
Omae Y, Ito S, Takeuchi M, Isa K, Ogasawara K, Kawabata K, Oda A, Kaito S, Tsuneyama H, Uchikawa M, Wada I, Ohto H, Tokunaga K
Transfusion 2019 Jul;59(7):2429-2435
Transfusion 2019 Jul;59(7):2429-2435
Muskelin Coordinates PrP(C) Lysosome versus Exosome Targeting and Impacts Prion Disease Progression.
Heisler FF, Pechmann Y, Wieser I, Altmeppen HC, Veenendaal L, Muhia M, Schweizer M, Glatzel M, Krasemann S, Kneussel M
Neuron 2018 Sep 19;99(6):1155-1169.e9
Neuron 2018 Sep 19;99(6):1155-1169.e9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 12555-1-AP( PrP Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PrP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PrP. This antibody recognizes human,mouse,rat antigen. The PrP antibody has been validated for the following applications: ELISA, IHC, WB analysis.
