Tissue expression
Cell line expression

SPPL2B

gene product
IMP4, KIAA1532, PSL1 
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

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73 antibodies from 15 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
LifeSpan BioSciences, Inc.
14 antibodies
antibodies-online
24 antibodies
Novus Biologicals
3 antibodies
Invitrogen Antibodies
3 antibodies
OriGene
2 antibodies
Aviva Systems Biology
2 antibodies
Atlas Antibodies
1 antibody
GeneTex
1 antibody
NovoPro Bioscience Inc.
2 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Biorbyt
12 antibodies
MyBioSource
1 antibody
Leading Biology
2 antibodies
GenWay
1 antibody
MilliporeSigma / Merck KGaA
1 antibody