BS8602

antibody from Bioworld Technology, Inc
Targeting: PLOD2 LH2
Provider product page for BS8602
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8602 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PLOD2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; Lysyl hydroxylase 2; LH2; PLOD2
Description
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PLOD2 protein structure - BS8602 shown in red.