Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B9505 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human PLOD2 monoclonal antibody, clone 509206
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 509206
- Vial size
- 100 _g
- Concentration
- 0.5 mg/ml
- Storage
- -20°C, Avoid Freeze/Thaw Cycles
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