CABT-B9505

antibody from Creative Diagnostics

Targeting: PLOD2 LH2

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-B9505

Provider

Creative Diagnostics

Product name

Mouse anti-Human PLOD2 monoclonal antibody, clone 509206

Antibody type

Monoclonal

Description

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

509206

Vial size

100 _g

Concentration

0.5 mg/ml

Storage

-20°C, Avoid Freeze/Thaw Cycles