Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11343-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11343-1-AP, RRID:AB_2103362
- Product name
- FGFR1OP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FGFR1OP antibody (Cat. #11343-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Postnatal Dynamic Ciliary ARL13B and ADCY3 Localization in the Mouse Brain.
Tubb4b is required for multi-ciliogenesis in the mouse.
Motor protein Kif6 regulates cilia motility and polarity in brain ependymal cells.
TTBK2 controls cilium stability by regulating distinct modules of centrosomal proteins.
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse.
rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis.
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity.
Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy.
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme.
The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.
Daughter centriole elongation is controlled by proteolysis.
Brewer KK, Brewer KM, Terry TT, Caspary T, Vaisse C, Berbari NF
Cells 2024 Jan 30;13(3)
Cells 2024 Jan 30;13(3)
Tubb4b is required for multi-ciliogenesis in the mouse.
Sewell MT, Legué E, Liem KF Jr
Development (Cambridge, England) 2024 Jan 1;151(1)
Development (Cambridge, England) 2024 Jan 1;151(1)
Motor protein Kif6 regulates cilia motility and polarity in brain ependymal cells.
Takagishi M, Yue Y, Gray RS, Verhey KJ, Wallingford JB
Disease models & mechanisms 2024 Feb 1;17(2)
Disease models & mechanisms 2024 Feb 1;17(2)
TTBK2 controls cilium stability by regulating distinct modules of centrosomal proteins.
Nguyen A, Goetz SC
Molecular biology of the cell 2023 Jan 1;34(1):ar8
Molecular biology of the cell 2023 Jan 1;34(1):ar8
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
Hall EA, Kumar D, Prosser SL, Yeyati PL, Herranz-Pérez V, García-Verdugo JM, Rose L, McKie L, Dodd DO, Tennant PA, Megaw R, Murphy LC, Ferreira MF, Grimes G, Williams L, Quidwai T, Pelletier L, Reiter JF, Mill P
eLife 2023 Feb 15;12
eLife 2023 Feb 15;12
Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse.
Van Sciver RE, Long AB, Katz HG, Gigante ED, Caspary T
Developmental biology 2023 Aug;500:1-9
Developmental biology 2023 Aug;500:1-9
rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis.
Hitomi Y, Aiba Y, Ueno K, Nishida N, Kawai Y, Kawashima M, Yasunami M, Gervais O, Ito M, Cordell HJ, Mells GF, Nagasaki M, Tokunaga K, Tsuiji M, Nakamura M
Journal of autoimmunity 2022 Jan;126:102775
Journal of autoimmunity 2022 Jan;126:102775
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.
Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, Reiter JF
Cell 2021 May 27;184(11):2911-2926.e18
Cell 2021 May 27;184(11):2911-2926.e18
Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity.
Xie C, Abrams SR, Herranz-Pérez V, García-Verdugo JM, Reiter JF
Developmental cell 2021 Dec 20;56(24):3334-3348.e6
Developmental cell 2021 Dec 20;56(24):3334-3348.e6
Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy.
Cabaud O, Roubin R, Comte A, Bascunana V, Sergé A, Sedjaï F, Birnbaum D, Rosnet O, Acquaviva C
Human molecular genetics 2018 Oct 1;27(19):3377-3391
Human molecular genetics 2018 Oct 1;27(19):3377-3391
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Tu HQ, Qin XH, Liu ZB, Song ZQ, Hu HB, Zhang YC, Chang Y, Wu M, Huang Y, Bai YF, Wang G, Han QY, Li AL, Zhou T, Liu F, Zhang XM, Li HY
Nature communications 2018 Dec 11;9(1):5277
Nature communications 2018 Dec 11;9(1):5277
CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme.
Mojarad BA, Gupta GD, Hasegan M, Goudiam O, Basto R, Gingras AC, Pelletier L
Open biology 2017 Jun;7(6)
Open biology 2017 Jun;7(6)
The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.
Kanie T, Abbott KL, Mooney NA, Plowey ED, Demeter J, Jackson PK
Developmental cell 2017 Jul 10;42(1):22-36.e12
Developmental cell 2017 Jul 10;42(1):22-36.e12
Daughter centriole elongation is controlled by proteolysis.
Korzeniewski N, Cuevas R, Duensing A, Duensing S
Molecular biology of the cell 2010 Nov 15;21(22):3942-51
Molecular biology of the cell 2010 Nov 15;21(22):3942-51
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 11343-1-AP(FGFR1OP antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FGFR1OP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FGFR1OP. This antibody recognizes human,mouse,rat antigen. The FGFR1OP antibody has been validated for the following applications: ELISA, WB, IHC analysis.