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Learn21663-1-AP
antibody from Proteintech Group
Targeting: RAB3GAP1
KIAA0066, RAB3GAP, RAB3GAP130, WARBM1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 21663-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21663-1-AP, RRID:AB_10863124
- Product name
- RAB3GAP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAB3GAP1 antibody (Cat. #21663-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references zDHHC9 Regulates Cardiomyocyte Rab3a Activity and Atrial Natriuretic Peptide Secretion Through Palmitoylation of Rab3gap1.
The Warburg micro syndrome protein RAB3GAP1 modulates neuronal morphogenesis and interacts with axon elongation end ER-Golgi trafficking factors.
Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons.
A tumor-specific modulation of heterogeneous ribonucleoprotein A0 promotes excessive mitosis and growth in colorectal cancer cells.
Manganese-induced alpha-synuclein overexpression impairs synaptic vesicle fusion by disrupting the Rab3 cycle in primary cultured neurons.
COPI-TRAPPII activates Rab18 and regulates its lipid droplet association.
Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP.
Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation.
VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Essandoh K, Subramani A, Ferro OA, Teuber JP, Koripella S, Brody MJ
JACC. Basic to translational science 2023 May;8(5):518-542
JACC. Basic to translational science 2023 May;8(5):518-542
The Warburg micro syndrome protein RAB3GAP1 modulates neuronal morphogenesis and interacts with axon elongation end ER-Golgi trafficking factors.
Ghate PS, Vacharasin JM, Ward JA, Nowling D, Kay V, Cowen MH, Lawlor MK, McCord M, Xu H, Carmona E, Cheon SH, Chukwurah E, Walla M, Lizarraga SB
Neurobiology of disease 2023 Aug;184:106215
Neurobiology of disease 2023 Aug;184:106215
Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons.
Liu Y, Tian F, Li S, Chen W, Gong W, Xie H, Liu D, Huang R, Liao W, Yi F, Zhou J
Amino acids 2021 Sep;53(9):1339-1350
Amino acids 2021 Sep;53(9):1339-1350
A tumor-specific modulation of heterogeneous ribonucleoprotein A0 promotes excessive mitosis and growth in colorectal cancer cells.
Konishi H, Fujiya M, Kashima S, Sakatani A, Dokoshi T, Ando K, Ueno N, Iwama T, Moriichi K, Tanaka H, Okumura T
Cell death & disease 2020 Apr 17;11(4):245
Cell death & disease 2020 Apr 17;11(4):245
Manganese-induced alpha-synuclein overexpression impairs synaptic vesicle fusion by disrupting the Rab3 cycle in primary cultured neurons.
Wang TY, Ma Z, Wang C, Liu C, Yan DY, Deng Y, Liu W, Xu ZF, Xu B
Toxicology letters 2018 Mar 15;285:34-42
Toxicology letters 2018 Mar 15;285:34-42
COPI-TRAPPII activates Rab18 and regulates its lipid droplet association.
Li C, Luo X, Zhao S, Siu GK, Liang Y, Chan HC, Satoh A, Yu SS
The EMBO journal 2017 Feb 15;36(4):441-457
The EMBO journal 2017 Feb 15;36(4):441-457
Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP.
Hong Y, Zhao T, Li XJ, Li S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Aug 24;36(34):8790-801
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Aug 24;36(34):8790-801
Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation.
Handley MT, Carpanini SM, Mali GR, Sidjanin DJ, Aligianis IA, Jackson IJ, FitzPatrick DR
Open biology 2015 Jun;5(6):150047
Open biology 2015 Jun;5(6):150047
VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.
Baron Y, Pedrioli PG, Tyagi K, Johnson C, Wood NT, Fountaine D, Wightman M, Alexandru G
BMC biology 2014 May 29;12:39
BMC biology 2014 May 29;12:39
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Gerondopoulos A, Bastos RN, Yoshimura S, Anderson R, Carpanini S, Aligianis I, Handley MT, Barr FA
The Journal of cell biology 2014 Jun 9;205(5):707-20
The Journal of cell biology 2014 Jun 9;205(5):707-20
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 21663-1-AP(RAB3GAP1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RAB3GAP1 antibody 21663-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-RAB3GAP1 (IP:21663-1-AP, 5ug; Detection:21663-1-AP 1:500) with mouse kidney tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 21663-1-AP(RAB3GAP1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
