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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 21052-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21052-1-AP, RRID:AB_10732809
- Product name
- UBXD2 antibody
- Antibody type
- Polyclonal
- Description
- UBXD2 antibody (Cat. #21052-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.
Acetylcholine exerts cytoprotection against hypoxia/reoxygenation-induced apoptosis, autophagy and mitochondrial impairment through both muscarinic and nicotinic receptors.
The p97-UBXN1 complex regulates aggresome formation.
Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury.
Ganji R, Paulo JA, Xi Y, Kline I, Zhu J, Clemen CS, Weihl CC, Purdy JG, Gygi SP, Raman M
Nature communications 2023 Feb 6;14(1):638
Nature communications 2023 Feb 6;14(1):638
UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.
Zheng J, Cao Y, Yang J, Jiang H
EMBO reports 2022 Oct 6;23(10):e54859
EMBO reports 2022 Oct 6;23(10):e54859
Acetylcholine exerts cytoprotection against hypoxia/reoxygenation-induced apoptosis, autophagy and mitochondrial impairment through both muscarinic and nicotinic receptors.
Intachai K, Chattipakorn SC, Chattipakorn N, Shinlapawittayatorn K
Apoptosis : an international journal on programmed cell death 2022 Apr;27(3-4):233-245
Apoptosis : an international journal on programmed cell death 2022 Apr;27(3-4):233-245
The p97-UBXN1 complex regulates aggresome formation.
Mukkavalli S, Klickstein JA, Ortiz B, Juo P, Raman M
Journal of cell science 2021 Apr 1;134(7)
Journal of cell science 2021 Apr 1;134(7)
Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury.
Hu C, Tian Y, Xu H, Pan B, Terpstra EM, Wu P, Wang H, Li F, Liu J, Wang X
The Journal of clinical investigation 2018 Dec 3;128(12):5294-5306
The Journal of clinical investigation 2018 Dec 3;128(12):5294-5306
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 21052-1-AP(UBXN4 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using UBXN4 antibody 21052-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 21052-1-AP(UBXN4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 21052-1-AP(UBXN4 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
