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- Antigen structure
- References [20]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 11749-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11749-1-AP, RRID:AB_2284481
- Product name
- PSMB1 antibody
- Antibody type
- Polyclonal
- Description
- PSMB1 antibody (Cat. #11749-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Citicoline Triggers Proteome Remodeling and Proteostatic Adaptation: Evidence from Shotgun Proteomics.
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures.
Proteostasis and autophagy disruption by the aging-related VGVAPG hexapeptide - preliminary insights into a potential novel elastin-induced neurodegeneration pathway in an in vitro human cellular neuron model.
Identifying potential mechanism and targets for treatment of tertiary lymphoid structure in lupus nephritis based on bioinformatics analysis.
Pharmacological induction of autophagy reduces inflammation in macrophages by degrading immunoproteasome subunits.
PTEN status determines therapeutic vulnerability to celastrol in cholangiocarcinoma.
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
An ankylosing spondylitis risk variant alters osteoclast differentiation.
Molecular alteration of the proteasome contributes to AD-like pathology in the brain of HFD-STZ diabetic rats.
Combinations of ivermectin with proteasome inhibitors induce synergistic lethality in multiple myeloma.
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Inhibition of the Proteasome Regulator PA28 Aggravates Oxidized Protein Overload in the Diabetic Rat Brain.
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins.
Selective Inhibition of the Immunoproteasome β5i Prevents PTEN Degradation and Attenuates Cardiac Hypertrophy.
PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε.
Quercetin Prevents In Vivo and In Vitro Myocardial Hypertrophy Through the Proteasome-GSK-3 Pathway.
Fibrosis, adipogenesis, and muscle atrophy in congenital muscular torticollis.
Proteomic analysis reveals that proteasome subunit beta 6 is involved in hypoxia-induced pulmonary vascular remodeling in rats.
Novel breast cancer metastasis-associated proteins.
Cavaterra D, Giammaria S, Pandino I, Zingale GA, Delli Paoli V, Fiore R, Michelessi M, Roberti G, Carnevale C, Tanga L, Cazzato D, Peroni E, Grasso G, Manni G, Bocedi A, Oddone F, Coletta M, Sbardella D, Tundo GR
Pharmaceutics 2026 Jan 1;18(1)
Pharmaceutics 2026 Jan 1;18(1)
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures.
Ding Y, Zuo Y, Zhang B, Fan Y, Xu G, Cheng Z, Ma S, Fang S, Tian A, Gao D, Xu X, Wang Q, Jing Y, Jiang M, Xiong M, Li J, Han Z, Sun S, Wang S, He F, Yang J, Qu J, Zhang W, Liu GH
Cell 2025 Oct 2;188(20):5763-5784.e26
Cell 2025 Oct 2;188(20):5763-5784.e26
Proteostasis and autophagy disruption by the aging-related VGVAPG hexapeptide - preliminary insights into a potential novel elastin-induced neurodegeneration pathway in an in vitro human cellular neuron model.
Skóra B, Szychowski KA
Neurochemistry international 2025 Jul;187:105992
Neurochemistry international 2025 Jul;187:105992
Identifying potential mechanism and targets for treatment of tertiary lymphoid structure in lupus nephritis based on bioinformatics analysis.
Zou M, Qian D, Luo R, Cheng Y, Xu G, Ge S
International immunopharmacology 2025 Feb 20;148:114084
International immunopharmacology 2025 Feb 20;148:114084
Pharmacological induction of autophagy reduces inflammation in macrophages by degrading immunoproteasome subunits.
Zhou J, Li C, Lu M, Jiang G, Chen S, Li H, Lu K
PLoS biology 2024 Mar;22(3):e3002537
PLoS biology 2024 Mar;22(3):e3002537
PTEN status determines therapeutic vulnerability to celastrol in cholangiocarcinoma.
Pan YF, Zhong L, Wang M, Jiang TY, Lin YK, Chen YB, Li X, Hu HP, Zhou HB, Yan HZ, Dong LW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155790
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Aug;131:155790
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
Wu Q, Liu WJ, Ma XY, Chang JS, Zhao XY, Liu YH, Yu XY
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
An ankylosing spondylitis risk variant alters osteoclast differentiation.
Wu F, Han X, Liu J, Zhang Z, Yan K, Wang B, Yang L, Zou H, Yang C, Huang W, Jin L, Wang J, Qian F, Niu Z
Rheumatology (Oxford, England) 2023 May 2;62(5):1980-1987
Rheumatology (Oxford, England) 2023 May 2;62(5):1980-1987
Molecular alteration of the proteasome contributes to AD-like pathology in the brain of HFD-STZ diabetic rats.
Gao H, Zhou Y, Jin PS, Wu DG, Wang YN, Zhao X, Zhao B
Metabolic brain disease 2023 Mar;38(3):1013-1024
Metabolic brain disease 2023 Mar;38(3):1013-1024
Combinations of ivermectin with proteasome inhibitors induce synergistic lethality in multiple myeloma.
Luo H, Feng Y, Wang F, Lin Z, Huang J, Li Q, Wang X, Liu X, Zhai X, Gao Q, Li L, Zhang Y, Wen J, Zhang L, Niu T, Zheng Y
Cancer letters 2023 Jul 1;565:216218
Cancer letters 2023 Jul 1;565:216218
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Wang Y, Wang C
Cell death and differentiation 2023 Jan;30(1):125-136
Cell death and differentiation 2023 Jan;30(1):125-136
Dual network analysis of transcriptome data for discovery of new therapeutic targets in non-small cell lung cancer.
Bai Y, Zhou L, Zhang C, Guo M, Xia L, Tang Z, Liu Y, Deng S
Oncogene 2023 Dec;42(49):3605-3618
Oncogene 2023 Dec;42(49):3605-3618
Inhibition of the Proteasome Regulator PA28 Aggravates Oxidized Protein Overload in the Diabetic Rat Brain.
Wu DG, Wang YN, Zhou Y, Gao H, Zhao B
Cellular and molecular neurobiology 2023 Aug;43(6):2857-2869
Cellular and molecular neurobiology 2023 Aug;43(6):2857-2869
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins.
Tian G, Hu C, Yun Y, Yang W, Dubiel W, Cheng Y, Wolf DA
The EMBO journal 2021 Jul 1;40(13):e106183
The EMBO journal 2021 Jul 1;40(13):e106183
Selective Inhibition of the Immunoproteasome β5i Prevents PTEN Degradation and Attenuates Cardiac Hypertrophy.
Xie X, Wang HX, Li N, Deng YW, Bi HL, Zhang YL, Xia YL, Li HH
Frontiers in pharmacology 2020;11:885
Frontiers in pharmacology 2020;11:885
PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε.
Wu F, Niu Z, Zhou B, Li P, Qian F
Viruses 2019 Jan 24;11(2)
Viruses 2019 Jan 24;11(2)
Quercetin Prevents In Vivo and In Vitro Myocardial Hypertrophy Through the Proteasome-GSK-3 Pathway.
Chen K, Rekep M, Wei W, Wu Q, Xue Q, Li S, Tian J, Yi Q, Zhang G, Zhang G, Xiao Q, Luo J, Liu Y
Cardiovascular drugs and therapy 2018 Feb;32(1):5-21
Cardiovascular drugs and therapy 2018 Feb;32(1):5-21
Fibrosis, adipogenesis, and muscle atrophy in congenital muscular torticollis.
Chen HX, Tang SP, Gao FT, Xu JL, Jiang XP, Cao J, Fu GB, Sun K, Liu SZ, Shi W
Medicine 2014 Nov;93(23):e138
Medicine 2014 Nov;93(23):e138
Proteomic analysis reveals that proteasome subunit beta 6 is involved in hypoxia-induced pulmonary vascular remodeling in rats.
Wang J, Xu L, Yun X, Yang K, Liao D, Tian L, Jiang H, Lu W
PloS one 2013;8(7):e67942
PloS one 2013;8(7):e67942
Novel breast cancer metastasis-associated proteins.
Ho J, Kong JW, Choong LY, Loh MC, Toy W, Chong PK, Wong CH, Wong CY, Shah N, Lim YP
Journal of proteome research 2009 Feb;8(2):583-94
Journal of proteome research 2009 Feb;8(2):583-94
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11749-1-AP(PSMB1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using PSMB1 antibody 11749-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11749-1-AP(PSMB1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
