ABIN310221

antibody from antibodies-online

Targeting: OTC OTCase

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN310221

Provider

antibodies-online

Product name

anti-Ornithine Carbamoyltransferase (OTC) (N-Term) antibody

Antibody type

Polyclonal

Antigen

The immunogen for anti-OTC antibody: synthetic peptide directed towards the N terminal of human OTC

Description

Protein A purified

Reactivity

Human, Mouse, Rat, Bovine, Canine, Porcine

Host

Rabbit

Antigen sequence

AFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKN
FTGEE IKYMLWLSAD


Epitope

N-Term

Vial size

100 μg

Concentration

1mg/mL

Storage

-20°C

Handling

Avoid repeated freeze-thaw cycles.

References

Submitted references

Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction.

Hallows WC, Yu W, Smith BC, Devries MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM
Molecular cell 2011 Jan 21;41(2):139-49

---

Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL
The Journal of biological chemistry 2009 May 15;284(20):13669-75

---

Hyperammonemia-induced encephalopathy due to ornithine transcarbamylase deficiency in an adult woman: identification of novel missense mutations.

Tanaka A, Wada T, Maruyama M, Tanaka A, Takikawa H, Komatsu Y
Journal of gastroenterology 2005 Jan;40(1):106-7