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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA000243 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA000243, RRID:AB_1079535
- Product name
- Anti-OTC
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human OTC, Gene description: ornithine carbamoyltransferase, Validated applications: WB, IHC, ICC, Uniprot ID: P00480, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress
Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes
Adult-Derived Human Liver Stem/Progenitor Cells Infused 3 Days Postsurgery Improve Liver Regeneration in a Mouse Model of Extended Hepatectomy
Candidate Serological Biomarkers for Cancer Identified from the Secretomes of 23 Cancer Cell Lines and the Human Protein Atlas
A Quantitative Proteomic Approach for Identification of Potential Biomarkers in Hepatocellular Carcinoma
Eldeeb M, Bayne A, Fallahi A, Goiran T, MacDougall E, Soumbasis A, Zorca C, Jones-Tabah J, Thomas R, Karpilovsky N, Mathur M, Durcan T, Trempe J, Fon E
Proceedings of the National Academy of Sciences 2024;121(10)
Proceedings of the National Academy of Sciences 2024;121(10)
Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion
Bishop E, Dimitrova M, Froggatt A, Estevez-Cebrero M, Storer L, Mussai F, Paine S, Grundy R, Dandapani M, Prodam F
BioMed Research International 2022;2022(1)
BioMed Research International 2022;2022(1)
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
Zabulica M, Srinivasan R, Akcakaya P, Allegri G, Bestas B, Firth M, Hammarstedt C, Jakobsson T, Jakobsson T, Ellis E, Jorns C, Makris G, Scherer T, Rimann N, van Zuydam N, Gramignoli R, Forslöw A, Engberg S, Maresca M, Rooyackers O, Thöny B, Häberle J, Rosen B, Strom S
Molecular Therapy 2021;29(5):1903-1917
Molecular Therapy 2021;29(5):1903-1917
Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes
Ginn S, Amaya A, Liao S, Zhu E, Cunningham S, Lee M, Hallwirth C, Logan G, Tay S, Cesare A, Pickett H, Grompe M, Dilworth K, Lisowski L, Alexander I
JHEP Reports 2020;2(1):100065
JHEP Reports 2020;2(1):100065
Adult-Derived Human Liver Stem/Progenitor Cells Infused 3 Days Postsurgery Improve Liver Regeneration in a Mouse Model of Extended Hepatectomy
Herrero A, Prigent J, Lombard C, Rosseels V, Daujat-Chavanieu M, Breckpot K, Najimi M, Deblandre G, Sokal E
Cell Transplantation 2017;26(2):351-364
Cell Transplantation 2017;26(2):351-364
Candidate Serological Biomarkers for Cancer Identified from the Secretomes of 23 Cancer Cell Lines and the Human Protein Atlas
Wu C, Hsu C, Chen C, Yu C, Chang K, Tai D, Liu H, Su W, Chang Y, Yu J
Molecular & Cellular Proteomics 2010;9(6):1100-1117
Molecular & Cellular Proteomics 2010;9(6):1100-1117
A Quantitative Proteomic Approach for Identification of Potential Biomarkers in Hepatocellular Carcinoma
Chaerkady R, Harsha H, Nalli A, Gucek M, Vivekanandan P, Akhtar J, Cole R, Simmers J, Schulick R, Singh S, Torbenson M, Pandey A, Thuluvath P
Journal of Proteome Research 2008;7(10):4289-4298
Journal of Proteome Research 2008;7(10):4289-4298
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and kidney tissues using HPA000243 antibody. Corresponding OTC RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
