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- Antibody Data
- Antigen structure
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- Immunohistochemistry [1]
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- Product number
- HPA031686 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA031686, RRID:AB_2673995
- Product name
- Anti-KYNU
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human KYNU, Gene description: kynureninase, Validated applications: WB, IHC, ICC, Uniprot ID: Q16719, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Cancer‐associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T‐cell suppression
Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion.
Itoh G, Takagane K, Fukushi Y, Kuriyama S, Umakoshi M, Goto A, Yanagihara K, Yashiro M, Tanaka M
Molecular Oncology 2021;16(1):166-187
Molecular Oncology 2021;16(1):166-187
Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion.
Hornigold N, Dunn KR, Craven RA, Zougman A, Trainor S, Shreeve R, Brown J, Sewell H, Shires M, Knowles M, Fukuwatari T, Maher ER, Burns J, Bhattarai S, Menon M, Brazma A, Scelo G, Feulner L, Riazalhosseini Y, Lathrop M, Harris A, Selby PJ, Banks RE, Vasudev NS
British journal of cancer 2020 Jul;123(1):137-147
British journal of cancer 2020 Jul;123(1):137-147
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and skeletal muscle tissues using HPA031686 antibody. Corresponding KYNU RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
