Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [50]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11854-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11854-1-AP, RRID:AB_2109336
- Product name
- GBP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GBP2 antibody (Cat. #11854-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Far-East Asian Toxoplasma isolates share ancestry with North and South/Central American recombinant lineages.
iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse.
GBP2 enhances paclitaxel sensitivity in triple‑negative breast cancer by promoting autophagy in combination with ATG2 and inhibiting the PI3K/AKT/mTOR pathway.
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity.
Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway.
A five-protein prognostic signature with GBP2 functioning in immune cell infiltration of clear cell renal cell carcinoma.
Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction.
GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy.
Guanylate-Binding Protein 2 Exerts GTPase-Dependent Anti-Ectromelia Virus Effect.
The Viral Protein Poly(A) Polymerase Catalytic Subunit Interacts with Guanylate-Binding Proteins 2 to Antagonize the Antiviral Ability of Targeting Ectromelia Virus.
GBP2 is a prognostic biomarker and associated with immunotherapeutic responses in gastric cancer.
Inducible nitric oxide synthase (iNOS) is necessary for GBP-mediated T. gondii restriction in murine macrophages via vacuole nitration and intravacuolar network collapse.
Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway.
Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype.
Insight into the Neuroprotective Effect of Genistein-3'-Sodium Sulfonate Against Neonatal Hypoxic-Ischaemic Brain Injury in Rats by Bioinformatics.
Toxoplasma IWS1 Determines Fitness in Interferon-γ-Activated Host Cells and Mice by Indirectly Regulating ROP18 mRNA Expression.
Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy.
GBP2 acts as a member of the interferon signalling pathway in lupus nephritis.
Enrichment of Newly Synthesized Proteins following treatment of C2C12 Myotubes with Endotoxin and Interferon-γ.
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
GBP2 serves as a novel prognostic biomarker and potential immune microenvironment indicator in renal cell carcinoma.
Single-cell RNA-seq reveals interferon-induced guanylate-binding proteins are linked with sarcopenia.
GBP2 as a potential prognostic biomarker in pancreatic adenocarcinoma.
Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity.
Macrophages Demonstrate Guanylate-Binding Protein-Dependent and Bacterial Strain-Dependent Responses to Francisella tularensis.
Galectin-3 regulates proinflammatory cytokine function and favours Brucella abortus chronic replication in macrophages and mice.
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization.
cGAS-STING effectively restricts murine norovirus infection but antagonizes the antiviral action of N-terminus of RIG-I in mouse macrophages.
Toxoplasma gondii GRA60 is an effector protein that modulates host cell autonomous immunity and contributes to virulence.
Cross-talk of pyroptosis and tumor immune landscape in lung adenocarcinoma.
Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock.
Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis.
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.
Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.
Lipopolysaccharide restricts murine norovirus infection in macrophages mainly through NF-kB and JAK-STAT signaling pathway.
GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway.
Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense.
Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.
Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses.
Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.
IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.
Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence.
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Ihara F, Kyan H, Takashima Y, Ono F, Hayashi K, Matsuo T, Igarashi M, Nishikawa Y, Hikosaka K, Sakamoto H, Nakamura S, Motooka D, Yamauchi K, Ichikawa-Seki M, Fukumoto S, Sasaki M, Ikadai H, Kusakisako K, Ohari Y, Yoshida A, Sasai M, Grigg ME, Yamamoto M
Nature communications 2024 May 22;15(1):4278
Nature communications 2024 May 22;15(1):4278
iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse.
Zhao XY, Lempke SL, Urbán Arroyo JC, Brown IG, Yin B, Magaj MM, Holness NK, Smiley J, Redemann S, Ewald SE
Nature communications 2024 Mar 27;15(1):2698
Nature communications 2024 Mar 27;15(1):2698
GBP2 enhances paclitaxel sensitivity in triple‑negative breast cancer by promoting autophagy in combination with ATG2 and inhibiting the PI3K/AKT/mTOR pathway.
Zhang W, Tang X, Peng Y, Xu Y, Liu L, Liu S
International journal of oncology 2024 Apr;64(4)
International journal of oncology 2024 Apr;64(4)
A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity.
Clayton BLL, Kristell JD, Allan KC, Cohn EF, Karl M, Jerome AD, Garrison E, Maeno-Hikichi Y, Sturno AM, Kerr A, Shick HE, Sepeda JA, Freundt EC, Sas AR, Segal BM, Miller RH, Tesar PJ
Nature neuroscience 2024 Apr;27(4):656-665
Nature neuroscience 2024 Apr;27(4):656-665
Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway.
Rao Y, Li J, Qiao R, Luo J, Liu Y
International immunopharmacology 2024 Apr 20;131:111686
International immunopharmacology 2024 Apr 20;131:111686
A five-protein prognostic signature with GBP2 functioning in immune cell infiltration of clear cell renal cell carcinoma.
Meng K, Li YY, Liu DY, Hu LL, Pan YL, Zhang CZ, He QY
Computational and structural biotechnology journal 2023;21:2621-2630
Computational and structural biotechnology journal 2023;21:2621-2630
Exploring the immune microenvironment of osteosarcoma through T cell exhaustion-associated gene expression: a study on prognosis prediction.
Zhu J, Yuan J, Arya S, Du Z, Liu X, Jia J
Frontiers in immunology 2023;14:1265098
Frontiers in immunology 2023;14:1265098
GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy.
Li X, Liu J, Zeng M, Yang K, Zhang S, Liu Y, Yin X, Zhao C, Wang W, Xiao L
Frontiers in immunology 2023;14:1127612
Frontiers in immunology 2023;14:1127612
Guanylate-Binding Protein 2 Exerts GTPase-Dependent Anti-Ectromelia Virus Effect.
Gao Z, Meng Z, He X, Chen G, Fang Y, Tian H, Zhang H, Jing Z
Microorganisms 2023 Sep 8;11(9)
Microorganisms 2023 Sep 8;11(9)
The Viral Protein Poly(A) Polymerase Catalytic Subunit Interacts with Guanylate-Binding Proteins 2 to Antagonize the Antiviral Ability of Targeting Ectromelia Virus.
Gao Z, He X, Chen G, Fang Y, Meng Z, Tian H, Zhang H, Jing Z
International journal of molecular sciences 2023 Oct 30;24(21)
International journal of molecular sciences 2023 Oct 30;24(21)
GBP2 is a prognostic biomarker and associated with immunotherapeutic responses in gastric cancer.
Wang Y, Pan J, An F, Chen K, Chen J, Nie H, Zhu Y, Qian Z, Zhan Q
BMC cancer 2023 Oct 2;23(1):925
BMC cancer 2023 Oct 2;23(1):925
Inducible nitric oxide synthase (iNOS) is necessary for GBP-mediated T. gondii restriction in murine macrophages via vacuole nitration and intravacuolar network collapse.
Zhao XY, Lempke SL, Urbán Arroyo JC, Yin B, Holness NK, Smiley J, Ewald SE
bioRxiv : the preprint server for biology 2023 Jul 25;
bioRxiv : the preprint server for biology 2023 Jul 25;
Guanine nucleotide-binding protein 2, GNBP2, accelerates the progression of clear cell renal cell carcinoma via regulation of STAT3 signaling transduction pathway.
Cao Q, Ma J, Li W, Hong P, Shen T, Tong M
Genes & genomics 2023 Jan;45(1):1-11
Genes & genomics 2023 Jan;45(1):1-11
Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype.
Korcari A, Nichols AEC, Buckley MR, Loiselle AE
eLife 2023 Jan 19;12
eLife 2023 Jan 19;12
Insight into the Neuroprotective Effect of Genistein-3'-Sodium Sulfonate Against Neonatal Hypoxic-Ischaemic Brain Injury in Rats by Bioinformatics.
Xie T, Shuang L, Liu G, Zhao S, Yuan Z, Cai H, Jiang L, Huang Z
Molecular neurobiology 2023 Feb;60(2):807-819
Molecular neurobiology 2023 Feb;60(2):807-819
Toxoplasma IWS1 Determines Fitness in Interferon-γ-Activated Host Cells and Mice by Indirectly Regulating ROP18 mRNA Expression.
Hashizaki E, Sasai M, Okuzaki D, Nishi T, Kobayashi T, Iwanaga S, Yamamoto M
mBio 2023 Feb 28;14(1):e0325622
mBio 2023 Feb 28;14(1):e0325622
Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy.
Li G, Choi JE, Kryczek I, Sun Y, Liao P, Li S, Wei S, Grove S, Vatan L, Nelson R, Schaefer G, Allen SG, Sankar K, Fecher LA, Mendiratta-Lala M, Frankel TL, Qin A, Waninger JJ, Tezel A, Alva A, Lao CD, Ramnath N, Cieslik M, Harms PW, Green MD, Chinnaiyan AM, Zou W
Cancer cell 2023 Feb 13;41(2):304-322.e7
Cancer cell 2023 Feb 13;41(2):304-322.e7
GBP2 acts as a member of the interferon signalling pathway in lupus nephritis.
Zhang Y, Liao Y, Hang Q, Sun D, Liu Y
BMC immunology 2022 Sep 17;23(1):44
BMC immunology 2022 Sep 17;23(1):44
Enrichment of Newly Synthesized Proteins following treatment of C2C12 Myotubes with Endotoxin and Interferon-γ.
Coleman CS, Stanley BA, Lang CH
Inflammation 2022 Jun;45(3):1313-1331
Inflammation 2022 Jun;45(3):1313-1331
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Xu H, Jin J, Chen Y, Wu G, Zhu H, Wang Q, Wang J, Li S, Grigore FN, Ma J, Chen CC, Lan Q, Li M
Oncogene 2022 Jul;41(31):3876-3885
Oncogene 2022 Jul;41(31):3876-3885
GBP2 serves as a novel prognostic biomarker and potential immune microenvironment indicator in renal cell carcinoma.
Tian Y, Wang H, Guan W, Tu X, Zhang X, Sun Y, Qian C, Song X, Peng B, Cui X
Molecular carcinogenesis 2022 Dec;61(12):1082-1098
Molecular carcinogenesis 2022 Dec;61(12):1082-1098
Single-cell RNA-seq reveals interferon-induced guanylate-binding proteins are linked with sarcopenia.
Peng Z, Zhang R, Kuang X, Yu C, Niu S, Du Y, Lu D, Li S, Teng Z, Lu S
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):2985-2998
Journal of cachexia, sarcopenia and muscle 2022 Dec;13(6):2985-2998
GBP2 as a potential prognostic biomarker in pancreatic adenocarcinoma.
Liu B, Huang R, Fu T, He P, Du C, Zhou W, Xu K, Ren T
PeerJ 2021;9:e11423
PeerJ 2021;9:e11423
Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity.
Chowdhury D, Gardner JC, Satpati A, Nookala S, Mukundan S, Porollo A, Landero Figueroa JA, Subramanian Vignesh K
Frontiers in immunology 2021;12:755961
Frontiers in immunology 2021;12:755961
Macrophages Demonstrate Guanylate-Binding Protein-Dependent and Bacterial Strain-Dependent Responses to Francisella tularensis.
Mohammadi N, Lindgren H, Yamamoto M, Martin A, Henry T, Sjöstedt A
Frontiers in cellular and infection microbiology 2021;11:784101
Frontiers in cellular and infection microbiology 2021;11:784101
Galectin-3 regulates proinflammatory cytokine function and favours Brucella abortus chronic replication in macrophages and mice.
Tana FL, Guimarães ES, Cerqueira DM, Campos PC, Gomes MTR, Marinho FV, Oliveira SC
Cellular microbiology 2021 Oct;23(10):e13375
Cellular microbiology 2021 Oct;23(10):e13375
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy.
Li G, Kryczek I, Nam J, Li X, Li S, Li J, Wei S, Grove S, Vatan L, Zhou J, Du W, Lin H, Wang T, Subramanian C, Moon JJ, Cieslik M, Cohen M, Zou W
Nature cell biology 2021 May;23(5):526-537
Nature cell biology 2021 May;23(5):526-537
Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization.
Pradipta A, Sasai M, Motani K, Ma JS, Lee Y, Kosako H, Yamamoto M
Life science alliance 2021 Jul;4(7)
Life science alliance 2021 Jul;4(7)
cGAS-STING effectively restricts murine norovirus infection but antagonizes the antiviral action of N-terminus of RIG-I in mouse macrophages.
Yu P, Miao Z, Li Y, Bansal R, Peppelenbosch MP, Pan Q
Gut microbes 2021 Jan-Dec;13(1):1959839
Gut microbes 2021 Jan-Dec;13(1):1959839
Toxoplasma gondii GRA60 is an effector protein that modulates host cell autonomous immunity and contributes to virulence.
Nyonda MA, Hammoudi PM, Ye S, Maire J, Marq JB, Yamamoto M, Soldati-Favre D
Cellular microbiology 2021 Feb;23(2):e13278
Cellular microbiology 2021 Feb;23(2):e13278
Cross-talk of pyroptosis and tumor immune landscape in lung adenocarcinoma.
Wang X, Lin W, Liu T, Xu Z, Wang Z, Cao Z, Feng X, Gao Y, He J
Translational lung cancer research 2021 Dec;10(12):4423-4444
Translational lung cancer research 2021 Dec;10(12):4423-4444
Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock.
Sakaguchi N, Sasai M, Bando H, Lee Y, Pradipta A, Ma JS, Yamamoto M
Frontiers in immunology 2020;11:561948
Frontiers in immunology 2020;11:561948
Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis.
Burke TP, Engström P, Chavez RA, Fonbuena JA, Vance RE, Welch MD
Nature microbiology 2020 May;5(5):688-696
Nature microbiology 2020 May;5(5):688-696
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.
Place DE, Briard B, Samir P, Karki R, Bhattacharya A, Guy CS, Peters JL, Frase S, Vogel P, Neale G, Yamamoto M, Kanneganti TD
PLoS pathogens 2020 Mar;16(3):e1008364
PLoS pathogens 2020 Mar;16(3):e1008364
Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.
Yu P, Li Y, Li Y, Miao Z, Peppelenbosch MP, Pan Q
The Journal of biological chemistry 2020 Jun 5;295(23):8036-8047
The Journal of biological chemistry 2020 Jun 5;295(23):8036-8047
Lipopolysaccharide restricts murine norovirus infection in macrophages mainly through NF-kB and JAK-STAT signaling pathway.
Yu P, Li Y, Wang Y, Peppelenbosch MP, Pan Q
Virology 2020 Jul;546:109-121
Virology 2020 Jul;546:109-121
GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway.
Yu S, Yu X, Sun L, Zheng Y, Chen L, Xu H, Jin J, Lan Q, Chen CC, Li M
Oncogene 2020 Jul;39(27):5042-5055
Oncogene 2020 Jul;39(27):5042-5055
Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense.
Lee Y, Yamada H, Pradipta A, Ma JS, Okamoto M, Nagaoka H, Takashima E, Standley DM, Sasai M, Takei K, Yamamoto M
Life science alliance 2020 Jan;3(1)
Life science alliance 2020 Jan;3(1)
Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection.
Briard B, Karki R, Malireddi RKS, Bhattacharya A, Place DE, Mavuluri J, Peters JL, Vogel P, Yamamoto M, Kanneganti TD
Nature microbiology 2019 Feb;4(2):316-327
Nature microbiology 2019 Feb;4(2):316-327
IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Karki R, Lee E, Place D, Samir P, Mavuluri J, Sharma BR, Balakrishnan A, Malireddi RKS, Geiger R, Zhu Q, Neale G, Kanneganti TD
Cell 2018 May 3;173(4):920-933.e13
Cell 2018 May 3;173(4):920-933.e13
LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.
Santos JC, Dick MS, Lagrange B, Degrandi D, Pfeffer K, Yamamoto M, Meunier E, Pelczar P, Henry T, Broz P
The EMBO journal 2018 Mar 15;37(6)
The EMBO journal 2018 Mar 15;37(6)
Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses.
Liu BC, Sarhan J, Panda A, Muendlein HI, Ilyukha V, Coers J, Yamamoto M, Isberg RR, Poltorak A
Cell reports 2018 Jul 3;24(1):155-168.e5
Cell reports 2018 Jul 3;24(1):155-168.e5
Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.
Costa Franco MM, Marim F, Guimarães ES, Assis NRG, Cerqueira DM, Alves-Silva J, Harms J, Splitter G, Smith J, Kanneganti TD, de Queiroz NMGP, Gutman D, Barber GN, Oliveira SC
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):607-622
Journal of immunology (Baltimore, Md. : 1950) 2018 Jan 15;200(2):607-622
IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.
Wallet P, Benaoudia S, Mosnier A, Lagrange B, Martin A, Lindgren H, Golovliov I, Michal F, Basso P, Djebali S, Provost A, Allatif O, Meunier E, Broz P, Yamamoto M, Py BF, Faudry E, Sjöstedt A, Henry T
PLoS pathogens 2017 Oct;13(10):e1006630
PLoS pathogens 2017 Oct;13(10):e1006630
Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence.
Li P, Jiang W, Yu Q, Liu W, Zhou P, Li J, Xu J, Xu B, Wang F, Shao F
Nature 2017 Nov 16;551(7680):378-383
Nature 2017 Nov 16;551(7680):378-383
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.
Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RKS, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD
Cell 2016 Oct 6;167(2):382-396.e17
Cell 2016 Oct 6;167(2):382-396.e17
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.
Meunier E, Wallet P, Dreier RF, Costanzo S, Anton L, Rühl S, Dussurgey S, Dick MS, Kistner A, Rigard M, Degrandi D, Pfeffer K, Yamamoto M, Henry T, Broz P
Nature immunology 2015 May;16(5):476-484
Nature immunology 2015 May;16(5):476-484
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
Man SM, Karki R, Malireddi RK, Neale G, Vogel P, Yamamoto M, Lamkanfi M, Kanneganti TD
Nature immunology 2015 May;16(5):467-75
Nature immunology 2015 May;16(5):467-75
RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.
Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 18;112(33):E4581-90
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 18;112(33):E4581-90
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Meunier E, Dick MS, Dreier RF, Schürmann N, Kenzelmann Broz D, Warming S, Roose-Girma M, Bumann D, Kayagaki N, Takeda K, Yamamoto M, Broz P
Nature 2014 May 15;509(7500):366-70
Nature 2014 May 15;509(7500):366-70
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human lung tissue were subjected to SDS PAGE followed by western blot with 11854-1-AP(GBP2 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GBP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GBP2. This antibody recognizes human, mouse, rat antigen. The GBP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
