ABIN500014

antibody from antibodies-online

Targeting: IL33 C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN500014

Provider

antibodies-online

Product name

anti-Interleukin 33 (IL33) (Center) antibody

Antibody type

Polyclonal

Antigen

IL-33 antibody was raised against a 19 amino acid peptide from near the center of human IL-33. (AP30427CP-N)

Description

Affinity chromatography purified via peptide column

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Center

Isotype

IgG

Vial size

0.1 mg

Storage

4°C

References

Submitted references

IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex.

Chackerian AA, Oldham ER, Murphy EE, Schmitz J, Pflanz S, Kastelein RA
Journal of immunology (Baltimore, Md. : 1950) 2007 Aug 15;179(4):2551-5

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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines.

Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan TK, Zurawski G, Moshrefi M, Qin J, Li X, Gorman DM, Bazan JF, Kastelein RA
Immunity 2005 Nov;23(5):479-90

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ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance.

Brint EK, Xu D, Liu H, Dunne A, McKenzie AN, O'Neill LA, Liew FY
Nature immunology 2004 Apr;5(4):373-9

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Interleukin-18, a proinflammatory cytokine.

Dinarello CA
European cytokine network 2000 Sep;11(3):483-6

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of IL-33 in human lymph node tissue lysate with AP30427PU-N IL-33 antibody at (A) 1 and (B) 2 ?g/ml.