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LearnALX-210-933-C100
antibody from Enzo Life Sciences
Targeting: IL33
C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV
Western blot
ELISA
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-210-933-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Product name
- IL-33 polyclonal antibody (AT110)
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Protein A-affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20¡C.
Submitted references Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.
Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation.
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo.
Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fievet N, Hauw JJ, DeKosky ST, Lemoine Y, Iwatsubo T, Wavrant-Devrièze F, Dartigues JF, Tzourio C, Buée L, Pasquier F, Berr C, Mann D, Lendon C, Alpérovitch A, Kamboh MI, Amouyel P, Lambert JC
Molecular psychiatry 2009 Nov;14(11):1004-16
Molecular psychiatry 2009 Nov;14(11):1004-16
Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation.
Küchler AM, Pollheimer J, Balogh J, Sponheim J, Manley L, Sorensen DR, De Angelis PM, Scott H, Haraldsen G
The American journal of pathology 2008 Oct;173(4):1229-42
The American journal of pathology 2008 Oct;173(4):1229-42
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo.
Carriere V, Roussel L, Ortega N, Lacorre DA, Americh L, Aguilar L, Bouche G, Girard JP
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 2;104(1):282-7
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 2;104(1):282-7
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Endogenous IL-33 is detected in the supernatant of THP1 using PAb to IL-33 (AT110) (Prod. No. ALX-210-933). Method: THP-1 cells were treated with PBS (lane 1), monosodium urate (MSU) (Prod. No. ALX-400-047) (lane 2) or peptidoglycan (PGN) (lane 3). The supernatants were collected, precipitated and loaded in a 15% SDS-gel. Western blot was performed using PAb to IL-33 (AT110) or a PAb to IL-1§ (cell signalling).
