RA0383

antibody from Oursmab

Targeting: IL33 C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0383

Provider

Oursmab

Product name

Itepekimab (Biosimilar Reference Antibody) (IL33)

Antibody type

Monoclonal

Description

Itepekimab is a fully human monoclonal antibody developed by Sanofi. It selectively targets and inhibits interleukin-33 (IL-33), a key alarmin cytokine involved in initiating and amplifying type 2 inflammatory responses in epithelial barriers (like the airways and skin). By blocking IL-33 signaling through its receptor ST2, itepekimab aims to treat inflammatory diseases driven by this pathway, with its most advanced clinical development in moderate-to-severe asthma and chronic obstructive pulmonary disease (COPD).

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Itepekimab (Biosimilar Reference Antibody) (IL33)-RA0383-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Itepekimab (Biosimilar Reference Antibody) (IL33)-RA0383 in a linear range of 15.63¨C125 ng/mL.