Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 13159-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13159-1-AP, RRID:AB_2092157
- Product name
- DHX36 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DHX36 antibody (Cat. #13159-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The RNA-Splicing Ligase RTCB Promotes Influenza A Virus Replication by Suppressing Innate Immunity via Interaction with RNA Helicase DDX1.
HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression.
Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome.
Lnc-SMaRT Translational Regulation of Spire1, A New Player in Muscle Differentiation.
Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome.
Translational control by DHX36 binding to 5'UTR G-quadruplex is essential for muscle stem-cell regenerative functions.
A 5' UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation.
SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase.
DExD/H-Box Helicase 36 Signaling via Myeloid Differentiation Primary Response Gene 88 Contributes to NF-κB Activation to Type 2 Porcine Reproductive and Respiratory Syndrome Virus Infection.
Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs.
Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.
Cao L, Hui X, Xu T, Mao H, Lin X, Huang K, Zhao L, Jin M
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 15;211(6):1020-1031
Journal of immunology (Baltimore, Md. : 1950) 2023 Sep 15;211(6):1020-1031
HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression.
Refaat AM, Nakata M, Husain A, Kosako H, Honjo T, Begum NA
Cell reports 2023 Mar 28;42(3):112284
Cell reports 2023 Mar 28;42(3):112284
Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome.
Guzzi N, Muthukumar S, Cieśla M, Todisco G, Ngoc PCT, Madej M, Munita R, Fazio S, Ekström S, Mortera-Blanco T, Jansson M, Nannya Y, Cazzola M, Ogawa S, Malcovati L, Hellström-Lindberg E, Dimitriou M, Bellodi C
Nature cell biology 2022 Mar;24(3):299-306
Nature cell biology 2022 Mar;24(3):299-306
Lnc-SMaRT Translational Regulation of Spire1, A New Player in Muscle Differentiation.
Scalzitti S, Mariani D, Setti A, Colantoni A, Lisi M, Bozzoni I, Martone J
Journal of molecular biology 2022 Jan 30;434(2):167384
Journal of molecular biology 2022 Jan 30;434(2):167384
Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome.
Ho JJD, Cunningham TA, Manara P, Coughlin CA, Arumov A, Roberts ER, Osteen A, Kumar P, Bilbao D, Krieger JR, Lee S, Schatz JH
Cell reports 2021 Oct 12;37(2):109806
Cell reports 2021 Oct 12;37(2):109806
Translational control by DHX36 binding to 5'UTR G-quadruplex is essential for muscle stem-cell regenerative functions.
Chen X, Yuan J, Xue G, Campanario S, Wang D, Wang W, Mou X, Liew SW, Umar MI, Isern J, Zhao Y, He L, Li Y, Mann CJ, Yu X, Wang L, Perdiguero E, Chen W, Xue Y, Nagamine Y, Kwok CK, Sun H, Muñoz-Cánoves P, Wang H
Nature communications 2021 Aug 19;12(1):5043
Nature communications 2021 Aug 19;12(1):5043
A 5' UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation.
Maltby CJ, Schofield JPR, Houghton SD, O'Kelly I, Vargas-Caballero M, Deinhardt K, Coldwell MJ
Nucleic acids research 2020 Sep 25;48(17):9822-9839
Nucleic acids research 2020 Sep 25;48(17):9822-9839
SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase.
Martone J, Mariani D, Santini T, Setti A, Shamloo S, Colantoni A, Capparelli F, Paiardini A, Dimartino D, Morlando M, Bozzoni I
EMBO reports 2020 Jun 4;21(6):e49942
EMBO reports 2020 Jun 4;21(6):e49942
DExD/H-Box Helicase 36 Signaling via Myeloid Differentiation Primary Response Gene 88 Contributes to NF-κB Activation to Type 2 Porcine Reproductive and Respiratory Syndrome Virus Infection.
Jing H, Zhou Y, Fang L, Ding Z, Wang D, Ke W, Chen H, Xiao S
Frontiers in immunology 2017;8:1365
Frontiers in immunology 2017;8:1365
Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs.
Lyons SM, Gudanis D, Coyne SM, Gdaniec Z, Ivanov P
Nature communications 2017 Oct 24;8(1):1127
Nature communications 2017 Oct 24;8(1):1127
Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.
Nie J, Jiang M, Zhang X, Tang H, Jin H, Huang X, Yuan B, Zhang C, Lai JC, Nagamine Y, Pan D, Wang W, Yang Z
Cell reports 2015 Oct 27;13(4):723-732
Cell reports 2015 Oct 27;13(4):723-732
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 13159-1-AP(DHX36 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate using 13159-1-AP(DHX36 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DHX36 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DHX36. This antibody recognizes human,mouse,rat antigen. The DHX36 antibody has been validated for the following applications: ELISA, WB, IHC analysis.