66911-1-Ig

antibody from Proteintech Group

Targeting: MAVS Cardif, IPS-1, KIAA1271, VISA

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66911-1-Ig

Provider

Proteintech Group

Product name

MAVS; VISA antibody

Antibody type

Monoclonal

Description

MAVS; VISA antibody (Cat. #66911-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1A8E9

Vial size

20ul, 150ul

References

Submitted references

The 3C-like serine protease activity of porcine astrovirus nsP1a/3 mediates mitochondrial apoptosis and MAVS cleavage to facilitate viral replication and antagonize type I interferon response.

Du Y, Lv Y, Feng X, Luo Y, Wei X, Shao S, Zhou Y, Ouyang K, Yin Y, Chen Y, Wei Z, Huang W, Qin Y
PLoS pathogens 2026 Feb;22(2):e1013987

---

Sclareol can effectively ameliorate Feline calicivirus induced lung injury via the inhibition of inflammation and apoptosis.

Yan Y, Yang M, Liu Z, Li L, Fu Z, Jiao Y, Li M, Li Y, Yao H, Shen Z, Peng G
International immunopharmacology 2025 Oct 30;164:115342

---

Bovine coronavirus Nsp14 protein promotes viral replication by degrading TRAF3 to inhibit interferon production.

Sun H, Liu Y, Yang X, Qin W, Lu X, Wang Y, Tong W, Yu H, Zheng H, Tong G, Shan T, Kong N
Veterinary microbiology 2025 Nov;310:110708

---

Bunyavirus SFTSV nucleoprotein exploits TUFM-mediated mitophagy to impair antiviral innate immunity.

Zhang WK, Yan JM, Chu M, Li B, Gu XL, Jiang ZZ, Li ZM, Liu PP, Yu TM, Zhou CM, Yu XJ
Autophagy 2025 Jan;21(1):102-119

---

Japanese encephalitis virus NS3 captures the protein translation element by interacting with HNRNPH1 to promote viral replication.

Wang X, Kong N, Wang C, Qin W, Yang X, Yu H, Tong W, Tong G, Li L, Zheng H, Shan T, Liu X
International journal of biological macromolecules 2025 Feb;289:138826

---

Carnosic Acid Directly Targets STING C-Terminal Tail to Improve STING-Mediated Inflammatory Diseases.

Mu W, Xu G, Li L, Wen J, Xiu Y, Zhao J, Liu T, Wei Z, Luo W, Yang H, Wu Z, Zhan X, Xiao X, Bai Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2417686

---

The structural protein VP3 of enterovirus D68 interacts with MAVS to inhibit the NF-κB signaling pathway.

Chen H, Huang M, Hou B, Liu Z, Tan R, Cui L, Wang T, Wang Z
Journal of virology 2025 Apr 15;99(4):e0016325

---

M1 Microglia-Derived Exosomes Promote A1 Astrocyte Activation and Aggravate Ischemic Injury via circSTRN3/miR-331-5p/MAVS/NF-κB Pathway.

Li Z, Xu P, Deng Y, Duan R, Peng Q, Wang S, Xu Z, Hong Y, Zhang Y
Journal of inflammation research 2024;17:9285-9305

---

Bunyavirus SFTSV NSs utilizes autophagy to escape the antiviral innate immune response.

Li ZM, Duan SH, Yu TM, Li B, Zhang WK, Zhou CM, Yu XJ
Autophagy 2024 Oct;20(10):2133-2145

---

TRIM26 facilitates PRV infection through NDP52-mediated autophagic degradation of MAVS.

Chengyue W, Mengdong W, Xiaoquan W, Yeping C, Hao L, Liumei S, Jianle R, Zhendong Z
Veterinary research 2024 Jul 4;55(1):84

---

TBK1 is involved in M-CSF-induced macrophage polarization through mediating the IRF5/IRF4 axis.

Li Y, Ji L, Liu C, Li J, Wen D, Li Z, Yu L, Guo M, Zhang S, Duan W, Yi L, Bi Y, Bu H, Li C, Liu Y
The FEBS journal 2024 Dec;291(23):5214-5235

---

Therapeutic efficacy of a novel self-assembled immunostimulatory siRNA combining apoptosis promotion with RIG-I activation in gliomas.

Chen J, Liu Z, Fang H, Su Q, Fan Y, Song L, He S
Journal of translational medicine 2024 Apr 29;22(1):395

---

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.

Yiu SPT, Zerbe C, Vanderwall D, Huttlin EL, Weekes MP, Gewurz BE
Molecular cell 2023 Jul 6;83(13):2367-2386.e15

---

DDX56 antagonizes IFN-β production to enhance EMCV replication by inhibiting IRF3 nuclear translocation.

Xu S, Xie J, Zhang X, Chen L, Bi Y, Li X, Idris A, Feng R
Veterinary microbiology 2022 Jan;264:109304

---

Targeting KDM4C enhances CD8(+) T cell mediated antitumor immunity by activating chemokine CXCL10 transcription in lung cancer.

Jie X, Chen Y, Zhao Y, Yang X, Xu Y, Wang J, Meng R, Zhang S, Dong X, Zhang T, Yang K, Xu S, Wu G
Journal for immunotherapy of cancer 2022 Feb;10(2)

---

Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.

Zhou Z, Sun Y, Xu J, Tang X, Zhou L, Li Q, Lan T, Ma J
Frontiers in immunology 2021;12:573078

---

Host protein, HSP90β, antagonizes IFN-β signaling pathway and facilitates the proliferation of encephalomyocarditis virus in vitro.

Li Q, Li X, Wu B, Niu Y, Ma R, Xie J, Ali A, Feng R
Virus research 2021 Nov;305:198547

---

Encephalomyocarditis Virus Abrogates the Interferon Beta Signaling Pathway via Its Structural Protein VP2.

Han Y, Xie J, Xu S, Bi Y, Li X, Zhang H, Idris A, Bai J, Feng R
Journal of virology 2021 Feb 24;95(6)