ABIN501120

antibody from antibodies-online

Targeting: MAVS Cardif, IPS-1, KIAA1271, VISA

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN501120

Provider

antibodies-online

Product name

anti-Mitochondrial Antiviral Signaling Protein (MAVS) (Middle Region) antibody

Antibody type

Polyclonal

Antigen

VISA antibody was raised against a 17 amino acid peptide from near the center of human VISA.

Description

Affinity chromatography

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Middle Region

Isotype

IgG

Vial size

0.1 mg

Storage

Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Antiviral innate immunity pathways.

Seth RB, Sun L, Chen ZJ
Cell research 2006 Feb;16(2):141-7

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VISA is an adapter protein required for virus-triggered IFN-beta signaling.

Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB
Molecular cell 2005 Sep 16;19(6):727-40

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J
Nature 2005 Oct 20;437(7062):1167-72

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of VISA in rat brain tissue lysate with AP30985PU-N at (A) 0.5, (B) 1 and (C) 2 ?g/ml.

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunohistochemistry of VISA in mouse brain tissue with AP30985PU-N at 2.5 ?g/ml.