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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 25897-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- KIF5C antibody
- Antibody type
- Polyclonal
- Description
- KIF5C antibody (Cat. #25897-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport.
Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients.
Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement.
Chen XQ, Das U, Park G, Mobley WC
Alzheimer's research & therapy 2021 Mar 10;13(1):59
Alzheimer's research & therapy 2021 Mar 10;13(1):59
Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients.
Yang TC, Yarmishyn AA, Yang YP, Lu PC, Chou SJ, Wang ML, Lin TC, Hwang DK, Chou YB, Chen SJ, Yu WK, Wang AG, Hsu CC, Chiou SH
Human molecular genetics 2020 Jun 3;29(9):1454-1464
Human molecular genetics 2020 Jun 3;29(9):1454-1464
Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement.
Wang Q, Tian J, Chen H, Du H, Guo L
Neurobiology of disease 2019 Jul;127:410-418
Neurobiology of disease 2019 Jul;127:410-418
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat brain tissue were subjected to SDS PAGE followed by western blot with 25897-1-AP( KIF5C Antibody) at dilution of 1:1500
- Validation comment
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of SH-SY5Y cells using 25897-1-AP( KIF5C Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- Validation comment
- IF
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human testis tissue slide using 25897-1-AP( KIF5C Antibody) at dilution of 1:50 (under 10x lens)
- Validation comment
- IHC
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human testis tissue slide using 25897-1-AP( KIF5C Antibody) at dilution of 1:50 (under 40x lens)
- Validation comment
- IHC
