ABIN1706142

antibody from antibodies-online

Targeting: TNFSF13B BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1706142

Provider

antibodies-online

Product name

anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human BAFF, different from the related rat and mouse sequence by three amino acids.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

-20°C

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis.

Lai Kwan Lam Q, King Hung Ko O, Zheng BJ, Lu L
Proceedings of the National Academy of Sciences of the United States of America 2008 Sep 30;105(39):14993-8

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BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma.

Krumbholz M, Theil D, Derfuss T, Rosenwald A, Schrader F, Monoranu CM, Kalled SL, Hess DM, Serafini B, Aloisi F, Wekerle H, Hohlfeld R, Meinl E
The Journal of experimental medicine 2005 Jan 17;201(2):195-200

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An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway.

Schiemann B, Gommerman JL, Vora K, Cachero TG, Shulga-Morskaya S, Dobles M, Frew E, Scott ML
Science (New York, N.Y.) 2001 Sep 14;293(5537):2111-4