MAB1357-100
antibody from R&D Systems
Targeting: TNFSF13B
BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
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- Product number
- MAB1357-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse BAFF/BLyS/TNFSF13B Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse BAFF in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse (rm) 4-1BB Ligand, rmEDA, rmFas Ligand, rmOX40 Ligand, rmTNF-alpha , rmTRANCE, rmTWEAK, recombinant human (rh) APRIL, rhBAFF, rhEDA-A2, rhGITR Ligand, rhLIGHT, rhLymphotoxin alpha 1/beta 2, rhLymphotoxin alpha 2/beta 1, rhTNF-alpha , rhTRAIL, rhVEGI, recombinant canine, cotton rat, equine, feline, porcine, or rat TNF-alpha .
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
Q9WU72
- Isotype
- IgG
- Antibody clone number
- 121808
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance.
Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment.
Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.
HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity.
B cell homeostasis and follicle confines are governed by fibroblastic reticular cells.
Nitric oxide regulates BAFF expression and T cell-independent antibody responses.
Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
Direct B cell stimulation by dendritic cells in a mouse model of lupus.
Matsushita T, Kobayashi T, Mizumaki K, Kano M, Sawada T, Tennichi M, Okamura A, Hamaguchi Y, Iwakura Y, Hasegawa M, Fujimoto M, Takehara K
Science advances 2018 Jul;4(7):eaas9944
Science advances 2018 Jul;4(7):eaas9944
Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment.
De Riva A, Wållberg M, Ronchi F, Coulson R, Sage A, Thorne L, Goodfellow I, McCoy KD, Azuma M, Cooke A, Busch R
PloS one 2017;12(8):e0181964
PloS one 2017;12(8):e0181964
Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.
Yasuda K, Watkins AA, Kochar GS, Wilson GE, Laskow B, Richez C, Bonegio RG, Rifkin IR
PloS one 2014;9(7):e103478
PloS one 2014;9(7):e103478
HIV-1 adenoviral vector vaccines expressing multi-trimeric BAFF and 4-1BBL enhance T cell mediated anti-viral immunity.
Kanagavelu S, Termini JM, Gupta S, Raffa FN, Fuller KA, Rivas Y, Philip S, Kornbluth RS, Stone GW
PloS one 2014;9(2):e90100
PloS one 2014;9(2):e90100
B cell homeostasis and follicle confines are governed by fibroblastic reticular cells.
Cremasco V, Woodruff MC, Onder L, Cupovic J, Nieves-Bonilla JM, Schildberg FA, Chang J, Cremasco F, Harvey CJ, Wucherpfennig K, Ludewig B, Carroll MC, Turley SJ
Nature immunology 2014 Oct;15(10):973-81
Nature immunology 2014 Oct;15(10):973-81
Nitric oxide regulates BAFF expression and T cell-independent antibody responses.
Giordano D, Draves KE, Li C, Hohl TM, Clark EA
Journal of immunology (Baltimore, Md. : 1950) 2014 Aug 1;193(3):1110-20
Journal of immunology (Baltimore, Md. : 1950) 2014 Aug 1;193(3):1110-20
Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
Scapini P, Hu Y, Chu CL, Migone TS, Defranco AL, Cassatella MA, Lowell CA
The Journal of experimental medicine 2010 Aug 2;207(8):1757-73
The Journal of experimental medicine 2010 Aug 2;207(8):1757-73
Direct B cell stimulation by dendritic cells in a mouse model of lupus.
Wan S, Zhou Z, Duan B, Morel L
Arthritis and rheumatism 2008 Jun;58(6):1741-50
Arthritis and rheumatism 2008 Jun;58(6):1741-50
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