BAF2106
antibody from R&D Systems
Targeting: TNFSF13B
BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- BAF2106 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse BAFF/BLyS/TNFSF13B Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse BAFF/BLyS/TNFSF13B in Western blots. In Western blots, approximately 40% cross-reactivity with recombinant human (rh) BAFF is observed, 10% cross-reactivity with recombinant mouse (rm) LIGHT and rhEDA-A2 is observed and less than 1% cross-reactivity with rmTWEAK, rhAPRIL, rmFas Ligand, rhGITR Ligand, rmOX40 Ligand, rmTNF-a, rmTRAIL and rm4-1BB Ligand is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
Q9WU72
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment.
Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
De Riva A, Wållberg M, Ronchi F, Coulson R, Sage A, Thorne L, Goodfellow I, McCoy KD, Azuma M, Cooke A, Busch R
PloS one 2017;12(8):e0181964
PloS one 2017;12(8):e0181964
Interferon regulatory factor-5 deficiency ameliorates disease severity in the MRL/lpr mouse model of lupus in the absence of a mutation in DOCK2.
Yasuda K, Watkins AA, Kochar GS, Wilson GE, Laskow B, Richez C, Bonegio RG, Rifkin IR
PloS one 2014;9(7):e103478
PloS one 2014;9(7):e103478
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace WW, Fagarasan S
Immunity 2010 Jul 23;33(1):71-83
Immunity 2010 Jul 23;33(1):71-83
Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
Scapini P, Hu Y, Chu CL, Migone TS, Defranco AL, Cassatella MA, Lowell CA
The Journal of experimental medicine 2010 Aug 2;207(8):1757-73
The Journal of experimental medicine 2010 Aug 2;207(8):1757-73
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