orb385959

antibody from Biorbyt

Targeting: TNFSF13B BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20

ELISA (Data presented on provider website)

Antibody Data

Product number

orb385959

Provider

Biorbyt

Product name

BAFF Antibody / BLyS

Antibody type

Monoclonal

Description

BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

C257/1638

Vial size

20 ug

Storage

BAFF antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.