318605

antibody from BioLegend
Targeting: TNFSF13B BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20
Provider product page for 318605

Antibody data

Product number
318605 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#318605, RRID:AB_830752
Product name
PE anti-human CD257 (BAFF, BLYS)
Antibody type
Monoclonal
Antigen
recombinant human BAFF(TL7) protein
Description
The T7-241 antibody recognizes human BAFF also known as B cell activating factor, tumor necrosis factor ligand superfamily 13B, B lymphocyte stimulator (BLYS), TNF and APOL-related leukocyte expressed ligand 1 (TALL1), and TNF homolog that activates apoptosis, NF-κB, and JNK (THANK). BAFF is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. BAFF can be proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homotrimers. The predicted molecular weight of a BAFF monomer is approximately 31 kD. BAFF is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-γ and downregulated by PMA/ionomycin treatment. The T7-241 antibody has been shown to be useful for flow cytometry and ELISA. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). The T7-241 antibody has been shown to be useful for flow cytometry and ELISA.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
TNFSF13B protein structure - 318605 shown in red.