RA0789

antibody from Oursmab

Targeting: TNFSF13B BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0789

Provider

Oursmab

Product name

Belimumab (Biosimilar Reference Antibody) (TNFSF13B)

Antibody type

Monoclonal

Description

Belimumab is a fully human, IgG1-lambda monoclonal antibody approved for the treatment of active, autoantibody-positive systemic lupus erythematosus (SLE) and active lupus nephritis. It functions as a B-lymphocyte stimulator (BLyS)-specific inhibitor. By binding to and neutralizing the soluble form of the cytokine BLyS (also known as BAFF), it prevents BLyS from interacting with its receptors on B cells. This inhibition reduces the survival and differentiation of autoreactive B cells, leading to a decrease in pathogenic autoantibody production and disease activity.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Belimumab (Biosimilar Reference Antibody) (TNFSF13B)-RA0789-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Belimumab (Biosimilar Reference Antibody) (TNFSF13B)-RA0789 in a linear range of 3.91-125 ng/mL.